cytokine production
[용어속성] Symptom
Implications of Oxidative Stress and Potential Role of Mitochondrial Dysfunction in COVID-19: Therapeutic Effects of Vitamin D
Review
[키워드] Activation
cell death
cellular homeostasis
consequence
contagiousness
contribute
COVID-19
cytokine production
Cytokines
death
decrease
deficiency
Effect
Evidence
Health
IMPROVE
individual
Inflammation
inflammatory process
inflammatory state
involved
knowledge
mitochondrial
mitochondrial dynamics
oxidative stress
Potential
pro-inflammatory state
Prognosis
provoke
recent
reduce
Regulation
renin-angiotensin-aldosterone system
risk
risk factor
role
ROS
SARS-CoV-2
SARS-COV-2 infection
syndrome
virus
Vitamin D
vitamin D level
[DOI] 10.3390/antiox9090897 PMC 바로가기 [Article Type] Review
[DOI] 10.3390/antiox9090897 PMC 바로가기 [Article Type] Review
Immunomodulatory Role of the Antimicrobial LL-37 Peptide in Autoimmune Diseases and Viral Infections
Review
[키워드] AMP
AMPs
antimicrobial
antimicrobial peptide
Antiviral
approach
autoantigen
autocrine
cascade
Cathelicidin
cytokine production
dendritic cell
disease
disease pathogenesis
disorders
dissemination
epidermal
epithelial cells
Express
expressed
expression
Factors
immune cells
immunomodulatory activity
immunomodulatory function
increase
induce
Infection
Inflammation
initiate
Innate immunity
interferon
limit
LL-37
lupus erythematosus
macrophages
Monocytes
Neutrophils
paracrine
produced
progression of disease
psoriasis
role
targeting
trauma
viral infections
virus
virus replication
[DOI] 10.3390/vaccines8030517 PMC 바로가기 [Article Type] Review
[DOI] 10.3390/vaccines8030517 PMC 바로가기 [Article Type] Review
COVID-19: Proposing a Ketone-Based Metabolic Therapy as a Treatment to Blunt the Cytokine Storm
Review Article
[키워드] activate
acute respiratory distress
adaptive
addressed
Anti-inflammatory
ARDS
Blood
blunt
boost
bypassing
carbohydrate
Cell
cell death
central metabolism
characterized
clinical study
complex
COVID-19 patient
cytokine production
Cytokine storm
decrease
distress
downregulate
energy metabolism
enzyme
fat
Fatality rate
function
Gene Expression
GPR109A
high mortality rate
Human
immune
immune function
Immunity
include
Infection
Influenza virus
inhibit
innate immune response
ketogenic
limitation
lung cell
metabolic
mice
mitochondrial metabolism
molecular
NLRP3 inflammasome
nucleotide
outcome
oxidative damage
Patient
pDC
proliferation
PROTECT
Protective
pyruvate
raise
reactive nitrogen specy
reactive oxygen specy
redox state
responsible
risk
RNS
ROS
SARS-COV-2 infection
shown
Signaling
storm
symptom severity
syndrome
T cell proliferation
T cell response
therapy
Transport
Treatment
virus-induced cytokine storm
[DOI] 10.1155/2020/6401341 PMC 바로가기 [Article Type] Review Article
[DOI] 10.1155/2020/6401341 PMC 바로가기 [Article Type] Review Article
Immune Response to COVID-19: Can We Benefit from the SARS-CoV and MERS-CoV Pandemic Experience?
Review
[키워드] antibody production
Can
CD4
CD8
Cellular immune response
complement system activation
coronavirus
correlation
Course
COVID-19
cytokine production
disease severity
effective
Epidemics
Fatality rate
Frequency
homology
humoral
Humoral immunity
immune response
immune system
Infection
infections
interferon
Local
MERS
MERS-CoV
Outbreaks
pandemic
Phylogenetic analysis
Protein
response
SARS
SARS-CoV
SARS-CoV-2
Sequencing
shown
Stage
T cell
T cell response
T cell responses
the SARS-CoV-2
therapy
Treatment
utility
Vaccine
Vaccine development
viral genome
[DOI] 10.3390/pathogens9090739 PMC 바로가기 [Article Type] Review
[DOI] 10.3390/pathogens9090739 PMC 바로가기 [Article Type] Review
IL-6 trans-signaling induces plasminogen activator inhibitor-1 from vascular endothelial cells in cytokine release syndrome
530
Published on
Journal: Proceedings of the National Academy of Sciences of [Category] COVID-19, MERS, SARS,
Journal: Proceedings of the National Academy of Sciences of [Category] COVID-19, MERS, SARS,
[키워드] accompanied
Activation
acute respiratory distress
ARDS
Bacteria
Bacterial
Bacterial infection
Bacterial sepsis
blockade
Burn
causes
chimeric antigen receptor
Clinical efficacy
clinical manifestation
coagulation cascade
COVID-19
COVID-19 patient
Critical
CRS
cytokine
cytokine production
Cytokine release syndrome
diagnosed
dysfunction
elevated
endothelial
Endothelial cell
Endothelial dysfunction
endotheliopathy
exhibited
highlight
Human monoclonal antibody
Hyperinflammatory
hyperinflammatory responses
IL-10
IL-6
IL-6 signaling
IL-8
Immunotherapy
in vitro data
indicate
induce
infections
Inflammation
involved
life-threatening
MCP-1
molecular mechanism
monocyte chemotactic protein-1
Pathogenesis
Patient
Proinflammatory cytokine
promoted
robust
Sepsis
severe COVID-19 patient
severe COVID-19 patients
Signaling
Significance
syndrome
systemic inflammatory response
T cell
therapy
Tocilizumab
trans-signaling
Treatment
vascular endothelial cell
[DOI] 10.1073/pnas.2010229117 PMC 바로가기 [Article Type] 530
[DOI] 10.1073/pnas.2010229117 PMC 바로가기 [Article Type] 530
Evidence for possible association of vitamin D status with cytokine storm and unregulated inflammation in COVID-19 patients
Original Article
[키워드] 25-hydroxyvitamin D
95% CI
95% confidence interval
a metric
adaptive
association
average
C-reactive protein
C-reactive protein (CRP
calculated
Case mortality ratio
Complication
Concentration
confirmed case
country
COVID-19
COVID-19 mortality
COVID-19 patient
COVID-19 patients
CRP
cytokine production
Cytokine storm
Deceased
deficiency
determine
Evidence
healthy subject
individual
Inflammation
investigated
Mortality
objective
Odds ratio
Patient
prevalence of COVID-19
reducing
Result
SARS-CoV-2
screening strategy
severe COVID-19
severe COVID-19 patient
severe COVID-19 patients
the mean
Vitamin D
Vitamin D status
was used
[DOI] 10.1007/s40520-020-01677-y PMC 바로가기 [Article Type] Original Article
[DOI] 10.1007/s40520-020-01677-y PMC 바로가기 [Article Type] Original Article
Drug repurposing and cytokine management in response to COVID-19: A review
Article
[키워드] “cytokine storm”
ACE-2
Activation
acute respiratory syndrome
Anti-inflammatory
anti-inflammatory activity
Anti-inflammatory therapy
antiparasitic drug
Antiviral
antivirals
attack
attenuate
caused
Clinical efficacy
Community
coronavirus
Coronavirus disease 2019
COVID-19
COVID-19 patient
COVID-19 patients
COVID‐19
cytokine
cytokine production
decrease
disease
drug
Drug repurposing
Fatality rate
Health
highlight
hyperinflammation
IL-6
illness
immunological
immunomodulating
Infection
Infectious disease
Injury
management
mechanism
mitigate
modulate
Mortality
multiple organ failure
New drug
organ damage
pandemic
Prevent
reduce
respiratory tract
SARS-CoV-2
SARS-COV-2 infection
Seasonal influenza
severe COVID-19
Supportive treatment
therapy
Topic
Treatment
utility
[DOI] 10.1016/j.intimp.2020.106947 PMC 바로가기 [Article Type] Article
[DOI] 10.1016/j.intimp.2020.106947 PMC 바로가기 [Article Type] Article
Immunomodulatory and Antiviral Activity of Metformin and Its Potential Implications in Treating Coronavirus Disease 2019 and Lung Injury
Immunology
[키워드] activity
addition
alleviate
animal models
antiviral activity
cause
clinical study
coronavirus disease
Coronavirus disease 2019
COVID-19
cytokine production
Cytokine storm
disease
drugs
Effect
excessive inflammation
fatality
immune
immunomodulatory activity
Infection
inhibit
inhibit SARS-CoV-2
inhibiting
Lung injury
Macrophage
metformin
Mortality
Multiple organ damage
NETs
Neutrophil extracellular trap
pandemic
pathogenesis of SARS-CoV-2
pathogenic
patients with COVID-19
Potential
Proinflammatory cytokine
proteomic study
reduce
retrospective
risk
SARS-CoV-2
SARS-COV-2 infection
severe lung injury
severity
Side effects
syndrome
T2D
Th1
Th17 cells
treat
treating
Treatment
type 2 diabete
with COVID-19
[DOI] 10.3389/fimmu.2020.02056 PMC 바로가기 [Article Type] Immunology
[DOI] 10.3389/fimmu.2020.02056 PMC 바로가기 [Article Type] Immunology
Is Antioxidant Therapy a Useful Complementary Measure for Covid-19 Treatment? An Algorithm for Its Application
Review
[키워드] accompanied
ACE2 receptor
Activation
acute lung injury
acute respiratory distress
alveolar
antioxidant
antioxidant therapy
application
bind
cause
cells
Characteristics
cleavage
Comorbidity
consequence
contribute
coronavirus 2
COVID-19
Critical
cytokine
cytokine production
Cytokine storm
cytotoxicity
death rate
distress
drug
elevated
ENhance
enzyme
eosinophil
free radical
Genes
help
hospital
Host
illness
immune response
IMPROVE
Inflammation
Inflammatory response
intensive care
leukocyte
lung
Macrophage
measure
mechanical ventilation
mechanism
mechanism of action
membrane
Monocytes
mortality rate
multiple organ dysfunction
Neutrophils
NFkB
Organ failure
oxidative stress
Oxidizing agent
oxygen exchange
Oxygenation
Pathogenesis
Patient
phagocytic
promote
protease
receptor
reduce
Release
respiratory
SARS-CoV-2
Sepsis
severe pneumonia
Stress
syndrome
tested
the SARS-CoV-2
therapeutic
therapy
tissue
Transcription
Transmissibility
virus
[DOI] 10.3390/medicina56080386 PMC 바로가기 [Article Type] Review
[DOI] 10.3390/medicina56080386 PMC 바로가기 [Article Type] Review