Development and performance evaluation of a rapid in-house ELISA for retrospective serosurveillance of SARS-CoV-2Research Article Published on 2021-02-022022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, [키워드] 95% CI 95% confidence interval affected biological samples Chemiluminescent assay clinical specificity Clinical symptoms Cohen’s kappa collected complement confirmed cases COVID-19 cross reaction cut-off demonstrated dengue patients develop development diagnostic methods Elecsy ELISA evaluate full-length healthy donor IgG in-house ELISA molecular Negative predictive value negative sample nucleocapsid pandemic positive Result retrospective RT-PCR positive patient SARS-CoV-2 SARS-CoV2 sensitivity serological test threshold Vaccine Variation was used [DOI] 10.1371/journal.pone.0246346 PMC 바로가기 [Article Type] Research Article
Clinical performance evaluation of a SARS-CoV-2 Rapid Antibody Test for determining past exposure to SARS-CoV-2SARS-CoV-2에 대한 과거 노출을 결정하기 위한 SARS-CoV-2 신속 항체 검사의 임상 성능 평가Article Published on 2021-02-012022-09-11 Journal: International Journal of Infectious Diseases [Category] MERS, SARS, 진단, 치료기술, [키워드] 95% CI Analytical specificity anti-SARS-CoV-2 antibodies antibody Antibody test antibody tests asymptomatic infection asymptomatic infections automated clinical collected common cold common cold symptoms conducted CoV cross-reactivity demonstrated EDTA Elecsy Elecsys failure rate IgG antibodies IgM/IgG immunoassay Past exposure Patient plasma point-of-care positive Prevalence Rapid rapid antibody test SARS-CoV-2 SARS-COV-2 infection Seropositivity specificity Test was tested was used Whole blood [DOI] 10.1016/j.ijid.2020.11.164 PMC 바로가기 [Article Type] Article
Seroprevalence of SARS-CoV-2-specific antibodies in the town of Ariano Irpino (Avellino, Campania, Italy): a population-based studyResearch Article Published on 2021-01-122022-10-31 Journal: Future Science OA [Category] COVID-19, [키워드] Abstract Analysis anti-SARS-CoV-2 anti-SARS-CoV-2 antibody antibody Ariano Irpino ASL asymptomatic individual Asymptomatic individuals Blood blood draw Campania conducted COVID-19 COVID-19 pandemic Department Elecsy Epidemiology females individual Infection Italian Italy males Naples organized pediatric cohort positive positive individual Prevalence proportion Public Public health intervention responsible Roche RT-PCR SARS Coronavirus SARS-CoV-2 SARS-CoV-2-specific antibody screening strategy serological seropositive Seroprevalence service Spread tested university virus [DOI] 10.2144/fsoa-2020-0203 PMC 바로가기 [Article Type] Research Article
Evaluation of Two Chemiluminescent and Three ELISA Immunoassays for the Detection of SARS-CoV-2 IgG Antibodies: Implications for Disease Diagnosis and Patients’ ManagementSARS-CoV-2 IgG 항체 검출을 위한 2가지 화학발광 및 3가지 ELISA 면역분석법 평가: 질병 진단 및 환자 관리에 미치는 영향Comparative Study Published on 2020-12-232022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 진단, 치료기술, [키워드] Abbott anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody anti-SARS-CoV-2 IgG anti-SARS-CoV-2 IgG antibodies anti-SARS-CoV-2 IgG antibody approach Asymptomatic asymptomatic patient best chemiluminescent Chemiluminescent assay chemiluminescent immunoassay collected commercial immunoassay COVID-19 COVID-19 patient COVID-19 patients demonstrated detection disease Elecsy ELISA ELISA assay ELISA assays estimation evaluate FIVE Follow-up General population Greece IgG IgG antibodies IgG antibody immunoassay immunoassays individual infected individuals N protein number of infected outbreak Prevalence S protein SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 N protein screening method screening methods sensitivity sera Seroprevalence serum significantly higher specificity specimen Symptom symptom onset the SARS-CoV-2 Volunteer [DOI] 10.3389/fimmu.2020.609242 PMC 바로가기 [Article Type] Comparative Study
Evidence and implications of pre‐existing humoral cross‐reactive immunity to SARS‐CoV‐2SARS-CoV-2에 대한 기존 체액 교차 반응성 면역의 증거 및 의미Original Research Published on 2020-12-152022-09-10 Journal: Immunity, Inflammation and Disease [Category] MERS, SARS, 진단, 치료법, [키워드] accumulating acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibodies antibody Antigen approach approaches building clinical trial collected coronavirus coronavirus disease Coronavirus disease 2019 Critical Elecsy healthcare healthy humoral Immunity Immunoglobulin immunoglobulins implication investigated knowledge nucleocapsid pandemic reactive reactivity respiratory respond Result SARS‐CoV‐2 sera serological severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 subject tested Vaccine Volunteer [DOI] 10.1002/iid3.367 PMC 바로가기 [Article Type] Original Research
The reliability of SARS-CoV-2 IgG antibody testing – a pilot study in asymptomatic health care workers in a Croatian university hospitalSARS-CoV-2 IgG 항체 검사의 신뢰성 – 크로아티아 대학 병원의 무증상 의료 종사자를 대상으로 한 파일럿 연구Research Article Published on 2020-12-012022-09-12 Journal: Croatian Medical Journal [Category] MERS, 진단, [키워드] 2019-nCoV Abbott Abbott SARS-CoV-2 IgG antibody Architect assays Asymptomatic automated center cut-off Elecsy Elecsys elevated evaluate evaluated False negative False negative rate False positive HCW Health care worker heterogeneity hospital IgG Immunoglobulin individuals Initially Patient pilot study positive produced reactivity reliability Result SARS-CoV-2 SARS-CoV-2 antigens SARS-CoV-2 IgG SARS-CoV-2 IgG antibody screened Serological assay tested university university hospital [DOI] 10.3325/cmj.2020.61.485 PMC 바로가기 [Article Type] Research Article
Performance characteristics of five immunoassays for SARS-CoV-2: a head-to-head benchmark comparisonSARS-CoV-2에 대한 5가지 면역분석의 성능 특성: 일대일 벤치마크 비교Comparative Study Published on 2020-12-012022-09-06 Journal: The Lancet. Infectious Diseases [Category] Communicable Disease, MERS, SARS, 진단, [키워드] (Abbott 384-well ELISA 95% CI Abbott acute respiratory syndrome acute respiratory syndrome coronavirus Basel benchmark study benefit best blood sample Blood samples can be used caused Characteristics Chicago collected coronavirus DiaSorin Effects Elecsy Elecsys finding FIVE funding Germany global pandemic head head-to-head assessment Health IgG immunoassay individual Italy laboratory-confirmed SARS-CoV-2 infection LIAISON Metrics Munich novel Oxford Oxford immunoassay Patient performance public health Public Health England receiver operating characteristic resource respiratory risk Risk assessment ROC Roche S1/S2 SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 IgG SARS-COV-2 infection sensitivity Sensitivity and specificity Serological testing serology severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Siemen Siemens specificity Surveillance Switzerland symptom onset Testing threshold thresholds Total USA were used [DOI] 10.1016/S1473-3099(20)30634-4 PMC 바로가기 [Article Type] Comparative Study
Clinical performance of three fully automated anti‐SARS‐CoV‐2 immunoassays targeting the nucleocapsid or spike proteinsResearch Article Published on 2020-12-012022-10-04 Journal: Journal of medical virology [Category] MERS, SARS, 진단, 치료법, [키워드] acute infection Analysis assays automated clinical clinical sensitivity coronavirus disease COVID‐19 COVID‐19 cut‐off Day demonstrated diagnose Elecsy ELISA Euroimmun IgG immunoassay Infection less LIAISON nucleocapsid Patient performed polymerase chain S1 and S2 SARS‐CoV‐2 SARS‐CoV‐2 sensitivities sensitivity sensitivity analysis sera serology significant difference specificity Spike protein symptom onset total antibodies [DOI] 10.1002/jmv.26669 PMC 바로가기 [Article Type] Research Article
Evaluation of the SARS-CoV-2-IgG response in outpatients by five commercial immunoassaysArticle Published on 2020-09-162022-10-31 Journal: GMS Infectious Diseases [Category] COVID-19, [키워드] Abbott ambulatory patients antibody Antibody Response Antigen assays association Asymptomatic collected commercial immunoassay Contact COVID-19 detect Elecsy evaluated FIVE Follow-up hospitalized COVID-19 patients hospitalized patients IgG IgG ELISA IgG response immunoassay immunoassays median novel onset of symptoms Outpatient Patient PCR-positive reported Roche S protein S1/S2 SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2-IgG sensitivity serology serum sample serum samples Seven total antibody while [DOI] 10.3205/id000066 PMC 바로가기 [Article Type] Article
Development and Validation of the Elecsys Anti-SARS-CoV-2 Immunoassay as a Highly Specific Tool for Determining Past Exposure to SARS-CoV-2Virology Published on 2020-08-032022-10-30 Journal: Journal of Clinical Microbiology [Category] COVID-19, SARS, [키워드] 95% CI 95% confidence interval acute respiratory syndrome agreement antibody calculated CIs Cohort collected coronavirus cross-reactivity demonstrated Determining development Diagnosis diagnostic Disease prevalence Donor Elecsy evaluated exposure to Hospitalized immunoassay majority neutralization testing Patient PCR-confirmed point estimate Population reactive resulting Roche Diagnostics SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2-specific antibodies sensitivity Sensitivity and specificity Specific specificity stomatitis validation [DOI] 10.1128/JCM.01694-20 PMC 바로가기 [Article Type] Virology