SARS-CoV-2 binding and neutralizing antibody levels after Ad26.COV2.S vaccination predict durable protection in rhesus macaquesAd26.COV2.S 백신 접종 후 SARS-CoV-2 결합 및 중화 항체 수준은 붉은털 원숭이의 지속적인 보호를 예측합니다Article Published on 2021-10-072022-09-10 Journal: Nature Communications [Category] MERS, SARS, 변종, 진단, [키워드] Ad26 Ad26.COV2.S Ad26.COV2.S vaccine Analysis Antibody titer Antibody titers approval authorization binding clinical development COVID-19 vaccine Efficacy Emergency use Evidence Human Immunity immunization immunogenicity immunological indicate knowledge Limited lung Lungs macaque natural infection Neutralizing antibodies neutralizing antibody other coronavirus other coronaviruses post vaccination predict predicted Predictive markers preliminary evidence Protective Protein Replication replication of SARS-CoV-2 rhesus macaque rhesus macaques SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike protein selected short-lived spike Spike protein the SARS-CoV-2 vaccination Vaccine Vaccines variant vector viral infection [DOI] 10.1038/s41467-021-26117-x PMC 바로가기 [Article Type] Article
Perspectives on the Orthopaedic Surgery Residency Application Process During the COVID-19 PandemicResearch Article Published on 2021-10-042022-10-29 Journal: JAAOS Global Research & Reviews [Category] Coronavirus, MERS, SARS, [키워드] addressed adopted application applied COVID-19 COVID-19 pandemic cross-sectional evaluate event Factor geographic location independent information lack less Limited orthopaedic surgery participated Perspective Process Program replicate replicated reported [DOI] 10.5435/JAAOSGlobal-D-21-00091 PMC 바로가기 [Article Type] Research Article
Non-invasive ventilation versus mechanical ventilation in hypoxemic patients with COVID-19COVID-19 저산소증 환자의 비침습적 환기 대 기계 환기Article Published on 2021-10-012022-09-11 Journal: Infection [Category] SARS, 변종, [키워드] 95% CI Analysis association Care cohort study conducted coronavirus disease COVID-19 COVID-19-related symptom COVID-19-related symptoms critical care outcomes death determine died discharge disease Final greater hospital hypoxemic ICU increased mortality Intervention laboratory-confirmed Limited Mechanical mechanical ventilation mechanical ventilator morbidity Mortality Multivariable regression NIV non-invasive ventilation outcome oxygen oxygen saturation pandemic participant Participants Patient patients patients with COVID-19 performed Randomized controlled trial Randomized controlled trials retrospective SARS-CoV-2 SpO2 study period subgroup subgroups survival Ventilation with COVID-19 [DOI] 10.1007/s15010-021-01633-6 PMC 바로가기 [Article Type] Article
Illness duration and symptom profile in symptomatic UK school-aged children tested for SARS-CoV-2Articles Published on 2021-10-012022-10-30 Journal: The Lancet. Child & adolescent health [Category] COVID-19, MERS, SARS, [키워드] 1:1 age analysed Analysis Anosmia approach artificial Asymptomatic cause Characteristics children children with COVID-19 Cohort college Council COVID COVID-19 Department determine Engineering Epidemiological study fatigue finding foundation funding Gender greater groups headache heart illness illness duration illness onset imaging Innovation intelligence IQR King Limited London median Medical Research Council mild illness Older pandemic participant persistent positive Prevalence prospective cohort study reported SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 test Science short duration Society Spearman Symptom symptom burden symptomatic Symptoms tested value Wellcome Trust were assessed were excluded [DOI] 10.1016/S2352-4642(21)00198-X PMC 바로가기 [Article Type] Articles
Risk Factors for Grade 3 to Grade 4 Adverse Reactions to the ChAdOx1 nCoV-19 Vaccine (AZD1222) Against SARS-CoV-2Medicine Published on 2021-09-302022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 95% CI 95% confidence interval adjusted adjusted odds ratio Adverse Adverse reactions Against age ARs AZD1222 being ChAdOx1 nCoV-19 ChAdOx1 nCoV-19 vaccine Comorbidities Coronavirus disease 2019 Diabetes Mellitus evaluated Factor female first dose GRADE grade 3 healthcare worker Healthcare workers increased risk Limited Local participant questionnaire reaction receiving risk factor Risk factors SARS-CoV-2 serious adverse reaction severity stratified university hospital [DOI] 10.3389/fmed.2021.738049 PMC 바로가기 [Article Type] Medicine
COVID-19 underscores the important role of Clinical Ethics Committees in AfricaResearch Article Published on 2021-09-252022-10-28 Journal: BMC Medical Ethics [Category] Coronavirus, Fulltext, SARS, [키워드] Africa African clinical Clinical ethics Clinical ethics committees Clinical ethics consultation services complex country COVID-19 COVID-19 pandemic ethics committee hcp health inequities healthcare Healthcare professional Healthcare systems Host Kenya lack of awareness Limited participated raised resource responses Result role South Africa supplementary material thematic analysis triggered while [DOI] 10.1186/s12910-021-00696-2 PMC 바로가기 [Article Type] Research Article
Outpatient and inpatient anticoagulation therapy and the risk for hospital admission and death among COVID-19 patientsResearch Paper Published on 2021-09-242022-10-04 Journal: EClinicalMedicine [Category] 유전자 메커니즘, [키워드] (n), number %, percentage ACEi, angiotensin-converting enzyme inhibitors age anticoagulation ARBs, angiotensin receptor blockers CI, confidence intervals CKD, chronic kidney disease clinics CO2, carbon dioxide COPD, Chronic obstructive pulmonary disease Coronavirus disease 2019 COVID-19 COVID-19 diagnosis COVID-19 patient COVID-19, Coronavirus disease 2019 D-dimer death deaths diagnosed with COVID-19 Diagnosis DIC, disseminated intravascular coagulation DOAC, direct oral anticoagulant EHR, electronic health records EMR, electronic medical records evaluated failure finding funding HCT, hematocrit HIT, heparin-induced thrombocytopenia hospital Hospital admission Hospitalization Hospitalized hospitalized COVID-19 patient HR, hazard ratio hypercoagulable increased mortality increased risk Inpatient investigated IPAC, inpatient anticoagulation therapy IRB, institutional review board Limited mg/dl, milligram per deciliter MI, prior myocardial infarction Mortality mortality risk multivariable analysis OPAC, outpatient persistent anticoagulation therapy Outpatient outpatients overall case-fatality rate Patient patients prospective cohort study RDW, red blood cell distribution width reduced risk reduction in risk RT-PCR, Reverse transcriptase-polymerase chain reaction SARS-COV-2, severe acute respiratory syndrome coronavirus-2 SBP-min, minimum systolic blood pressure SBP, systolic blood pressure SD, standard deviations SE, standard errors SpO2-min, minimum oxygen saturation T1DM, type 1 diabetes mellitus T2DM, type 2 diabetes mellitus the patient therapy treated USA VTE, venous thromboembolism was obtained WBC, White blood cell with COVID-19 [DOI] 10.1016/j.eclinm.2021.101139 PMC 바로가기 [Article Type] Research Paper
COVID-19 Vaccines for HIV-Infected PatientsHIV에 감염된 환자를위한 COVID-19 백신Review Published on 2021-09-222022-09-01 Journal: Viruses [Category] SARS, 진단, [키워드] adaptive AIDS appear can be used clinical trial complementary Complementary DNA COVID-19 COVID-19 pandemic COVID-19 vaccine COVID-19 vaccines death defense mechanisms Diagnosis disease entity DNA effective enzyme etiologic agent General population helper T cell helper T cells HIV HIV infection HIV/AIDS HIV/AIDS patients immune defense immune parameter immune systems Immunocompromised immunodeficiency disease implementation include infecting Infection initial lead Limited mechanism microbial molecular test Molecular tests mRNA new virus outcomes Pathogens PCR progeny Protective reverse transcriptase Safe SARS-CoV-2 SARS-CoV-2 vaccines shown susceptibility susceptible T cell T cells transcriptase unique vaccination Vaccine variety Viral Viral RNA virus wake [DOI] 10.3390/v13101890 PMC 바로가기 [Article Type] Review
Pre-Exposure Prophylaxis (PrEP) Uptake among Black Men Who Have Sex with Men (BMSM) in the Southern U.S.미국 남부에서 남성과 성관계를 가진 흑인 남성(BMSM)의 노출 전 예방(PrEP) 섭취Commentary Published on 2021-09-152022-09-10 Journal: International Journal of Environmental Research an [Category] SARS, 치료제, [키워드] affected age approach approaches benefit black BMSM Care common Community complex condoms COVID-19 COVID-19 pandemic effective exacerbated facilitator facilitators healthcare healthcare providers Healthcare systems HIV HIV testing homophobia incidence Intervention limit Limited men misinformation offer pandemic poverty precautions PrEP Prophylaxis rapid expansion reduce Sex South Southern states Stigma the United State United States uptake [DOI] 10.3390/ijerph18189715 PMC 바로가기 [Article Type] Commentary
One Health Investigation of SARS-CoV-2 Infection and Seropositivity among Pets in Households with Confirmed Human COVID-19 Cases—Utah and Wisconsin, 2020인간의 Covid-19 사례가 확인 된 가구의 애완 동물 사이의 SARS-Cov-2 감염 및 혈청 양성에 대한 건강 조사-2020 년 우타와 위스콘신Article Published on 2021-09-122022-09-10 Journal: Viruses [Category] Fulltext, SARS, 조류인플루엔자, 치료기술, [키워드] cat Confirmed Contact contact with COVID-19 COVID-19 diagnosis detectable Diagnosis dog eight eligible enrolled for inclusion greater household household transmission Households Human Infection investigation laboratory-confirmed Laboratory-confirmed COVID-19 Limited median nasal one health Oropharyngeal Patient people with COVID-19 pets positive proportion rectal swab restrict rRT-PCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 neutralizing antibodies serological results seropositive Seropositivity Swab tested Transmission with COVID-19 zoonoses [DOI] 10.3390/v13091813 PMC 바로가기 [Article Type] Article