Evaluation of cleaning and disinfection protocols for severe acute respiratory coronavirus virus 2 (SARS-CoV-2) on different hospital surfacesLetter to the Editor Published on 2021-01-252022-10-30 Journal: Infection Control and Hospital Epidemiology [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] hospital protocol Respiratory Coronavirus SARS-CoV-2 virus [DOI] 10.1017/ice.2021.23 PMC 바로가기 [Article Type] Letter to the Editor
Prevalence of SARS-CoV-2 Infection in Children and Their Parents in Southwest Germany독일 남서부 어린이와 부모의 SARS-CoV-2 감염 유병률Multicenter Study Published on 2021-01-222022-09-12 Journal: JAMA Pediatrics [Category] MERS, SARS, 진단, [키워드] 95% CI acute respiratory syndrome antibody appear assumption children Combination conducted consequence Contact coronavirus COVID-19 COVID-19 pandemic cross-sectional enrolled enzyme-linked immunosorbent enzyme-linked immunosorbent assay exposure finding Germany immunoassays immunofluorescence Importance Infection lockdown measure median age men multicenter Nasopharyngeal swab novel coronavirus disease objective outcome pandemic parent participant Point positive Potential prevalence study provide Relevance Respiratory Coronavirus Result SARS-CoV-2 SARS-CoV-2 antibody SARS-COV-2 infection SARS-CoV-2 RNA SARS-CoV-2 seroprevalence School seronegative Seronegativity serum serum sample setting specific IgG antibody Spread tested unlikely virus-neutralizing [DOI] 10.1001/jamapediatrics.2021.0001 PMC 바로가기 [Article Type] Multicenter Study
Stenoparib, an Inhibitor of Cellular Poly(ADP-Ribose) Polymerase, Blocks Replication of the SARS-CoV-2 and HCoV-NL63 Human Coronaviruses In Vitro세포성 폴리(ADP-리보스) 중합효소 억제제인 스테노파립, 시험관 내에서 SARS-CoV-2 및 HCoV-NL63 인간 코로나바이러스 복제 차단Research Article Published on 2021-01-192022-09-10 Journal: mBio [Category] 신약개발, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition approval approved arsenal block Calu Calu-3 caused cell entry cells clinical trial Concentration coronavirus coronavirus disease Coronavirus disease 2019 Coronaviruses COVID-19 death determined by dosage dose-dependent downstream drug drug combination effective evaluated exhibit experiments facilitate growth HCoV-NL63 Human human lung impede in vitro Infection inhibit inhibitor inhibitory kidney lung adenocarcinoma New NL63 ovarian cancer pandemic PARP polymerase Protective Remdesivir repurposing respiratory Respiratory Coronavirus SARS-CoV-2 severe acute respiratory syndrome Coronavirus Spread Stage stenoparib suppressed synergistic synergistic effect the SARS-CoV-2 therapy Treatment Vaccine Vero E6 Viral viral replication [DOI] 10.1128/mBio.03495-20 PMC 바로가기 [Article Type] Research Article
SARS-CoV-2 Genomic Variation in Space and Time in Hospitalized Patients in Philadelphia필라델피아 입원 환자의 공간 및 시간에 따른 SARS-CoV-2 게놈 변이Research Article Published on 2021-01-192022-09-10 Journal: mBio [Category] 변종, 유전자 메커니즘, 치료기술, [키워드] accelerated accumulation B.1 circulating city clade collected comparison coronavirus COVID-19 Critical D614G substitution disease Epidemic First wave followed by Genome genome sequence Genome sequences Genome sequencing GISAID hospitalized patient hospitalized patients infected individual infected individuals Infection initial isolate isolates Lineage lineages midsummer Multiple New York Nextstrain outbreak outcome patients Philadelphia polymorphism Polymorphisms respiratory Respiratory Coronavirus SARS-CoV-2 SARS-COV-2 infection sequence sequences Sequencing severe acute respiratory coronavirus Space Spread spring the epidemic time Transmission understanding variant Viral viral spike [DOI] 10.1128/mBio.03456-20 PMC 바로가기 [Article Type] Research Article
Characterization of handheld disinfectant sprayers for effective surface decontamination to mitigate severe acute respiratory coronavirus virus 2 (SARS-CoV-2) transmissionResearch Brief Published on 2021-01-132022-10-30 Journal: Infection Control and Hospital Epidemiology [Category] COVID-19, MERS, SARS, [키워드] characterization effective mitigate Respiratory Coronavirus SARS-CoV-2 Transmission virus [DOI] 10.1017/ice.2020.1423 PMC 바로가기 [Article Type] Research Brief
Detection of severe acute respiratory coronavirus virus 2 (SARS-CoV-2) in outpatients: A multicenter comparison of self-collected saline gargle, oral swab, and combined oral–anterior nasal swab to a provider collected nasopharyngeal swab외래 환자에서 중증 급성 호흡기 코로나바이러스 바이러스 2(SARS-CoV-2) 검출: 자가 채취 식염수 가글, 구강 면봉 및 구강-전 비강 면봉을 제공자에서 수집한 비인두 면봉과 다기관 비교Multicenter Study Published on 2021-01-132022-09-10 Journal: Infection Control and Hospital Epidemiology [Category] MERS, SARS, 진단, 치료기술, [키워드] 95% CI adjusted Canada Characteristics collected coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Cycle threshold value demonstrated detection disadvantage Disadvantages E-gene median multicenter nasal swab Nasopharyngeal swab oral swab oral swabs overcome populations Positive test reference standard respiratory Respiratory Coronavirus SARS-CoV-2 SARS-CoV-2 detection sensitivity specimen Spread Swab the SARS-CoV-2 Toronto virus were assessed [DOI] 10.1017/ice.2021.2 PMC 바로가기 [Article Type] Multicenter Study
Routine surveillance of asymptomatic healthcare personnel for severe acute respiratory coronavirus virus 2 (SARS-CoV-2): Not a prevention strategyCommentary Published on 2021-01-112022-10-30 Journal: Infection Control and Hospital Epidemiology [Category] COVID-19, MERS, SARS, [키워드] Asymptomatic healthcare personnel Respiratory Coronavirus routine Surveillance virus [DOI] 10.1017/ice.2020.1428 PMC 바로가기 [Article Type] Commentary
Rapid design and development of CRISPR-Cas13a targeting SARS-CoV-2 spike proteinSARS-CoV-2 스파이크 단백질을 표적으로 하는 CRISPR-Cas13a의 신속한 설계 및 개발Research Paper Published on 2021-01-012022-09-10 Journal: Theranostics [Category] 신약개발, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 anti-SARS-CoV-2 Antiviral approach AT2 bioinformatics candidate caused cells cleavage coronavirus Coronaviruses COVID-19 CRISPR CRISPR-Cas13a disease effective Efficiency Epidemic HepG2 Host identify in-silico Invasion molecular docking offer provide Rapid respiratory Respiratory Coronavirus Result RNA RNA-editing robust SARS-CoV-2 SARS-CoV-2 spike protein selected sequence Sequence alignment Spike protein Structure tested the spike protein therapeutic therapeutic target Viral protein Viral proteins [DOI] 10.7150/thno.51479 PMC 바로가기 [Article Type] Research Paper
Evidence-based of conjunctival COVID-19 positivity: An Italian experience: Gemelli Against COVID Group결막 COVID-19 양성의 증거 기반: 이탈리아 경험: COVID-19에 반대하는 GemelliOriginal Research Articles Published on 2020-12-232022-09-11 Journal: European Journal of Ophthalmology [Category] MERS, SARS, 치료기술, [키워드] Against blood chemistry C-reactive protein C-RP Care Chest radiography clinical parameter clinical trials Computed tomography Conjunctiva conjunctival Conjunctival swab conjunctival swabs conjunctivitis coronavirus COVID COVID-19 D-dimer Dyspnea enrolled Eye infection ferritin fibrinogen FIVE four groups group highest Hospitalized impairment Infection Italian Lactate lactate dehydrogenase LDH lowest Nasopharyngeal swab NPs ophthalmologists outcome oxygen oxygen saturation Patient patients hospitalized patients with SARS-CoV-2 Personalized medicine positive precautionary measures pulmonary pulmonary impairment radiologic respiratory Respiratory Coronavirus SARS-CoV-2 SARS-COV-2 infection secondary outcome Secondary outcomes severe acute respiratory coronavirus severe pulmonary impairment significantly statistically Swab swabs tears Transmission Trial registration virus [DOI] 10.1177/1120672120976548 PMC 바로가기 [Article Type] Original Research Articles
Designing of a next generation multiepitope based vaccine (MEV) against SARS-COV-2: Immunoinformatics and in silico approachesSARS-COV-2에 대한 차세대 멀티에피토프 기반 백신(MEV) 설계: 면역정보학 및 인실리코 접근법Research Article Published on 2020-12-222022-08-13 Journal: PLoS ONE [Category] Biochemistry, COVID-19, MERS, SARS, [키워드] adjuvant Amino acid amino acids analyses antigenic antigenic proteins approach B-cell binding affinity caused conducted coronavirus coronavirus disease Coronavirus disease 2019 Coverage COVID-19 demonstrated effective epitope Epitopes Escherichia coli Escherichia coli K-12 system flexible followed by global health security highly antigenic HLA-binding allele HLA-binding alleles human pathogenic toll-like receptors immunogenic profile in silico In silico cloning increased expression indicated K-12 linker MEV MEV codon MEV codons MEV construct MHC class MHC class I MHC class II epitopes molecular molecular docking molecular dynamics multiepitope based vaccine non-allergenic overlapping pandemic pathogenic predicted Protein respiratory Respiratory Coronavirus selected Selected epitopes severe acute respiratory coronavirus significant interaction T-cell target targets Till TLR TLR3 TLR8 Toll-like receptor Vaccine vaccine against SARS-COV-2 vaccine production [DOI] 10.1371/journal.pone.0244176 PMC 바로가기 [Article Type] Research Article