Antibody Responses to SARS-CoV-2 Following an Outbreak Among Marine Recruits With Asymptomatic or Mild Infection무증상 또는 경증 감염이 있는 해병 모집단의 발병 후 SARS-CoV-2에 대한 항체 반응Immunology Published on 2021-06-092022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 진단, 치료기술, 치료법, [키워드] Adults age antibodies Asymptomatic asymptomatic infection Betacoronavirus circulating Cohort comparable COVID-19 cross-reactivity disease domain Endemic enrolled focus healthy Humoral response humoral responses IgA antibodies IgA antibody IgG IgG antibodies IgG antibody Infection investigated Longitudinal studies longitudinal study Mild Mild disease mild SARS-CoV-2 infection mild symptoms Multiplex assay neutralization activity Neutralizing activity no decrease nucleocapsid outbreak participant polyclonal Population positive positive correlation Protein RBD recruit remained reported respiratory Respiratory illness response S protein S proteins SARS-CoV-2 SARS-CoV-2 IgG SARS-COV-2 infection SARS-CoV-2 RBD SARS-CoV-2 spike sera serological response significantly spring tested young adults zoonotic [DOI] 10.3389/fimmu.2021.681586 PMC 바로가기 [Article Type] Immunology
Smokers’ cognitive and behavioural reactions during the early phase of the COVID-19 pandemic: Findings from the 2020 ITC Four Country Smoking and Vaping SurveyCovid-19 Pandemic의 초기 단계에서 흡연자의인지 및 행동 반응 : 2020 ITC Four Country Smoking and Vaping Survey의 연구 결과Clinical Trial Published on 2021-06-042022-08-13 Journal: PLoS ONE [Category] MERS, SARS, 임상, [키워드] Analysis association behavioural belief Canada change changes in cognitive conducted confirmed case confirmed cases country COVID-19 cross-sectional cross-sectional study death early phase England examined Factor females finding Government greater health belief Health Belief Model highest immune Impact Infection ITC less lockdowns lowest majority Model National Nicotine nicotine dependence Other pandemic positive public health reaction reduce reduced reducing Regression Regression analyses reported respiratory Respiratory illness response responses Result risk severity of COVID-19 significantly lower smoker Smokers smoking social distancing Stress survey susceptibility susceptibility to infection thinking thought United State United States Wave [DOI] 10.1371/journal.pone.0252427 PMC 바로가기 [Article Type] Clinical Trial
The Emergence of SARS-CoV-2 Variant(s) and Its Impact on the Prevalence of COVID-19 Cases in the Nabatieh Region, LebanonSARS-CoV-2 변이체의 출현과 레바논 나바티에 지역에서 COVID-19 사례의 확산에 미치는 영향Article Published on 2021-06-022022-09-10 Journal: Medical Sciences [Category] MERS, SARS, 변종, 치료기술, [키워드] analyzed association asymptomatic infection Care caused China circulating city collected Community coronavirus coronavirus disease coronavirus disease-2019 country COVID-19 COVID-19 case COVID-19 cases Critical death demonstrated effective intervention emergence global pandemic Health Health care Health Organization Impact infect Infection Lebanon less lockdown lockdown restriction lockdown restrictions measure mortality rate mortality rates Nasopharyngeal swab nasopharyngeal swab sample Nasopharyngeal swab samples New Novel coronavirus objective occur outbreak outcome populations positive Positive test Prevalence prevalence of COVID-19 prevalence rate prevalence rates raised referred to Region respiratory Respiratory illness respiratory tract Result SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants SARS-CoV-2 virus South Spread suspected patient suspected patients Transmissibility variant Variation WHO World Health Organization Wuhan Year [DOI] 10.3390/medsci9020040 PMC 바로가기 [Article Type] Article
The Recombination Potential between SARS-CoV-2 and MERS-CoV from Cross-Species Spill-over Infections종간 전파 감염으로 인한 SARS-CoV-2와 MERS-CoV의 재조합 가능성Article Published on 2021-06-012022-09-11 Journal: Journal of Epidemiology and Global Health [Category] SARS, 유전자 메커니즘, 조류인플루엔자, 치료기술, [키워드] acute respiratory syndrome coronavirus alveolar cell alveolar cells angiotensin angiotensin converting enzyme both virus both viruses Cell Cluster Co-infection coronavirus 2 COVID-19 cross-over dipeptidyl peptidase Dipeptidyl peptidase-4 dromedary camels feasible generate Genes high recombination Host humans identify infect mechanisms MERS MERS-CoV Middle-Eastern Respiratory Syndrome Coronavirus ORF1a ORF1b organelle outbreak Pneumonia Potential recognizing Recombination Replication respiratory Respiratory illness respiratory illnesses RNA SARS-CoV-2 sequence sequence homology severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Spike protein Spike proteins Transcription Transcription Regulatory Sequences TRS TRSs virus whole genome [DOI] 10.2991/jegh.k.201105.001 PMC 바로가기 [Article Type] Article
Epidemiological Correlates of Polymerase Chain Reaction Cycle Threshold Values in the Detection of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2) 검출에서 중합효소 연쇄 반응 주기 역치의 역학적 상관관계Article Published on 2021-06-012022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 치료기술, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age chain Chain Reaction Characteristics collected Concentration coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 correlated Course COVID-19 Ct value Ct values cycle cycle threshold detection elapsed epidemiological Epidemiology examined highest household transmission individual Infection lowest median Mild no symptom no symptoms participant performed polymerase chain polymerase chain reaction reaction reported respiratory Respiratory illness Result RT-PCR sample collection SARS-CoV-2 SARS-COV-2 infection semi-quantitative severe acute respiratory syndrome Coronavirus significantly significantly lower Symptom symptom onset the median upper respiratory symptom upper respiratory symptoms value Viral load Viral RNA viral shedding [DOI] 10.1093/cid/ciaa1469 PMC 바로가기 [Article Type] Article
Myelin oligodendrocyte glycoprotein antibody-associated optic neuritis in a COVID-19 patient A case report코로나19 환자의 수초 희소돌기아교세포 당단백질 항체 관련 시신경염 증례보고Case Reports Published on 2021-05-142022-09-12 Journal: Medicine [Category] SARS, 진단, [키워드] Admission antibody aquaporin Autoimmune response Case report Chain Reaction clinical manifestations Complete coronavirus disease Coronavirus disease 2019 Course COVID-19 COVID-19 patient diagnosed discharge eye pain Follow-up followed by glycoprotein had no IgG Immunoglobulin Immunoglobulin G indicated infected individual infected individuals intensity Laboratory testing left eye magnetic resonance imaging Methylprednisolone MOG multiple organ multiple organs Myelin myelin oligodendrocyte glycoprotein antibody optic nerve Optic neuritis orbit Outpatient past pathogen Pathogens Patient PCR polymerase chain polymerase chain reaction positive Prednisolone pulse reported Respiratory illness Spread steroid tested therapy Treatment response was performed [DOI] 10.1097/MD.0000000000025865 PMC 바로가기 [Article Type] Case Reports
Comparing COVID-19 and Influenza Presentation and TrajectoryMedicine Published on 2021-05-142022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] Acute respiratory infection addition Admission affected age Analysis analyzed Biomarker Biomarkers Blood body mass index Campus Coagulation Comorbidity COVID-19 COVID-19 group COVID-19 patient COVID-19 patients Critical demographics disease disease trajectory electronic medical record ENhance functions Glucose group Haifa help Hospitalization Hospitalized immune response in-hospital mortality include individual Influenza intrinsic knowledge lab metabolism neutrophil Older Other Pathogenesis Patient patients presentation Prevalence Pulse rate Respiratory function Respiratory illness respiratory illnesses SARI suffered trajectory Treatment variable virulence vital sign was performed White blood cell [DOI] 10.3389/fmed.2021.656405 PMC 바로가기 [Article Type] Medicine
Increased complement activation is a distinctive feature of severe SARS-CoV-2 infection증가된 보체 활성화는 심각한 SARS-CoV-2 감염의 독특한 특징입니다Research Articles Published on 2021-05-132022-09-10 Journal: Science Immunology [Category] 바이오마커, [키워드] Activation Acute respiratory failure Alternative complement pathway angiopoietin Care circulating clinical trials complement Complement activation Complement pathway contributing to COVID-19 Critical Critical illness distinctive feature Drug discovery elevated endothelial injury enrolled facilitate feature higher risk hypercoagulability ICU ICU admission identify implicated IMV Increased Infection Influenza intensive care intensive care unit Invasive mechanical ventilation investigated marker Medicine Non-COVID-19 Organ failure outcome Pathogenesis pathway Pathways Patient patients hospitalized patients with COVID-19 plasma prevalent respiratory Respiratory failure Respiratory illness risk SARS-COV-2 infection School severe COVID-19 severe SARS severe SARS-CoV-2 target thrombomodulin two tertiary care centers university von Willebrand factor Washington [DOI] 10.1126/sciimmunol.abh2259 PMC 바로가기 [Article Type] Research Articles
Reducing Morbidity and Mortality Rates from COVID-19, Influenza and Pneumococcal Illness in Nursing Homes and Long-Term Care Facilities by Vaccination and Comprehensive Infection Control InterventionsArticle Published on 2021-05-082022-10-31 Journal: Geriatrics [Category] COVID-19, [키워드] Admission automatically triggered interventions Care CDC Comprehensive comprehensive infection control interventions Control COVID-19 COVID-19 pandemic disease transmission Effectiveness Evidence facility hand washing HEPA filter home identify illness implementation individual individual room fresh air entry and venting infection control Influenza Intervention long-term care homes Masks measure meta-analyses MONITOR Mortality Multimorbidity Nursing nursing homes Patient pneumococcal disease pneumococcal illness PPE problem quarantine Rate reduce Regional resources Respiratory illness respiratory infections Respiratory tract infections risk Risk of bias SARS-CoV-2 searched social distancing systematic review temperature vaccinate vaccination variant Ventilation with COVID-19 [DOI] 10.3390/geriatrics6020048 PMC 바로가기 [Article Type] Article
Convalescent plasma for adults with acute COVID-19 respiratory illness (CONCOR-1): study protocol for an international, multicentre, randomized, open-label trial급성 COVID-19 호흡기 질환이 있는 성인을 위한 회복기 혈장(CONCOR-1): 국제, 다기관, 무작위 배정, 공개 시험을 위한 연구 프로토콜Study Protocol Published on 2021-05-042022-09-01 Journal: Trials [Category] SARS, 임상, 진단, 치료기술, 치료제, [키워드] acute COVID-19 acute respiratory syndrome Analysis anti-SARS-CoV-2 antibodies antibodies antibody titres baseline Blood Group CCP Community community acquired community acquired pneumonia CONCOR-1 convalescent plasma coronavirus COVID-19 COVID-19 infection criteria death detect detectable anti-SARS-CoV-2 antibodies detectable anti-SARS-CoV-2 antibody determine Donor donors Ebola Ebola virus Efficacy and safety estimation Evidence exclusion criteria Exploratory analyses global pandemic hospital include inclusion criteria independent Infection Influenza information intensive care interim analysis International Intubated intubation Middle East Middle East respiratory syndrome multicentre NCT04348656 Neutralization assay neutralization assays Non-intubated Novel coronavirus Open-label outcome oxygen Patient patients with SARS-CoV-2 plasma Pneumonia Primary outcome quantified randomization Randomized Randomized controlled trial randomized trial reaction receive receiving recruitment reduce reduction in Relative risk respiratory respiratory complication Respiratory complications Respiratory illness respiratory symptom respiratory symptoms responsible risk risk reduction Sample size SARS-CoV-2 SARS-CoV-2 antibody titre SARS-CoV-2 antibody titres SARS-COV-2 infection SARS-CoV-2 viral load secondary Secondary outcomes Serious Adverse Events Serologically Severe acute respiratory syndrome Standard of care Study protocol supplemental oxygen Support syndrome threshold thresholds titre transfusion reactions Trial two-sided Ventilator-free days Viral viral disease Viral diseases Viral load with COVID-19 [DOI] 10.1186/s13063-021-05235-3 PMC 바로가기 [Article Type] Study Protocol