Disease‐duration based comparison of subsets of immune cells in SARS CoV‐2 infected patients presenting with mild or severe symptoms identifies prognostic markers for severity경증 또는 중증 증상을 나타내는 SARS CoV-2 감염 환자의 면역 세포 하위 집합의 질병 기간 기반 비교는 중증도에 대한 예후 마커를 식별합니다.Comparative Study Published on 2021-01-162022-09-12 Journal: Immunity, Inflammation and Disease [Category] MERS, SARS, 진단, [키워드] absence adaptive adaptive immune cells Adaptive immunity addition Analysis analyzed Antibody titer association B cells CD8 T cells Cell dendritic cells determined by disease disease severity event expression flow cytometry follicular forms Frequency functional healthy subject help Humoral immunity Hyperactivation identification identify IgG IL‐6 Imbalance Immune cell immune cells Immune profile India indicated infected patient Infection innate immune cell Innate immune cells Lower lymphocyte Lymphocytes management material maturation mDC mDCs memory B cell memory B cells Mild modulation Monocytes Multivariate analysis Neutralizing antibody titer neutralizing antibody titers NK cells observation Older age pandemic Pathogenesis Patient patient cohort patients positive presenting PRNT PRNT50 Prognostic marker Prognostic markers receptor Result SARS CoV‐2 SARS‐CoV‐2 SARS‑CoV2 Severe case severe cases severe disease severe symptom severity Spectrum subset Symptoms T cell T cells T helper cells therapy understanding [DOI] 10.1002/iid3.402 PMC 바로가기 [Article Type] Comparative Study
Spectrum of Chest Dual-Energy Computed Tomography Findings in COVID Patients in North IndiaRadiology Published on 2021-01-042022-10-31 Journal: Cureus [Category] COVID-19, [키워드] abnormality acute respiratory syndrome age America analyzed Atypical calculated Care Chest Comorbidities Comorbidity Computed tomography consolidation coronavirus COVID COVID 19 Covid patients COVID-19 COVID-19 patient crazy-paving pattern dect distribution Dyspnoea elicited enrolled evaluated female finding GGO ground-glass opacity group India intermediate type lung lung parenchyma majority male Mild symptom North North America Patient patients Pneumonia positive Prevalence prevalent reported Result RTPCR SARS-CoV-2 Society Spectrum subjects the patient vessel was done was recorded [DOI] 10.7759/cureus.12489 PMC 바로가기 [Article Type] Radiology
Spectrum of neuroimaging findings in COVID-19Pictorial Review Published on 2021-01-012022-10-27 Journal: The British Journal of Radiology [Category] COVID-19, MERS, [키워드] change China Complication COVID-19 Critical Critically ill Encephalopathy feature Hemorrhagic hospitalized COVID-19 hospitalized patient hypertensive hypoxic include infections manifestation multiple sclerosis outbreak positive patient Spectrum spread to state stroke syndrome Venous thrombosis Virus Disease worldwide pandemic [DOI] 10.1259/bjr.20200812 PMC 바로가기 [Article Type] Pictorial Review
Characterization of the cytokine storm reflects hyperinflammatory endothelial dysfunction in COVID-19사이토카인 폭풍의 특성은 COVID-19의 과염증성 내피 기능 장애를 반영합니다Article Published on 2021-01-012022-09-11 Journal: The Journal of Allergy and Clinical Immunology [Category] SARS, 바이오마커, 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 ADP-ribose Adult patients age Analysis analyzed assays association attenuate Baricitinib Biomarker Biomarkers blood sample Blood samples cardiovascular cardiovascular disease characterization characterized circulating circulation coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 CXCL10 CXCL5 CXCL9 cytokine Cytokine storm Cytokine storms disease severity dominant dysregulation endothelial damage Endothelial dysfunction healthy control healthy controls help host inflammatory response host response Hyperinflammatory identify IFN-γ IL-10 IL-1ra IL-6 immune response immune responses increasingly Infection Inflammation Intervention marker MCP-3 mechanism Mild moderate monocyte observé Ordinal Scale Pathogenesis Patient patients hospitalized patients with COVID-19 physician platform polymerase Protein proteomic pursuit reduce reflect Regulation reliability reproducibility respiratory Result scale severe acute respiratory syndrome Coronavirus Spectrum statistically significant stratified the cytokine storm therapeutic options Vascular with COVID-19 [DOI] 10.1016/j.jaci.2020.08.031 PMC 바로가기 [Article Type] Article
Clinical analysis and pluripotent stem cells-based model reveal possible impacts of ACE2 and lung progenitor cells on infants vulnerable to COVID-19임상 분석 및 만능 줄기 세포 기반 모델은 COVID-19에 취약한 유아에 대한 ACE2 및 폐 전구 세포의 가능한 영향을 보여줍니다Multicenter Study Published on 2021-01-012022-09-01 Journal: Theranostics [Category] 진단, 치료기술, [키워드] ACE2 ACE2 expression age Alveolar Type II analysed Analysis angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 biopsies Cell cells children children with COVID-19 clinical clinical feature Clinical features Cohort Combination contributing to cooperation coronavirus disease Coronavirus disease 2019 COVID-19 derivative develop developmental developmental stages disease severity distribution double positive cell double positive cells Ex vivo examined expressed expression expression level expression levels expression pattern expression patterns immune response immune system Impact Infant Infants infections lung lung biopsies lung cell lung cells lung development lung injuries Lung injury lung progenitor cells Lungs number of children Older pluripotent stem cells Pneumonia positive profiles progenitor cell progenitor cells reported risk factor Risk factors RNA-sequencing SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pseudovirus SARS-CoV-2 virus severe coronavirus disease significantly single cell RNA sequencing SOX9 Spectrum Stage stem cell Type vulnerability with COVID-19 [DOI] 10.7150/thno.53136 PMC 바로가기 [Article Type] Multicenter Study
COVID-19: The experience from IranCOVID-19: 이란의 경험Article Published on 2021-01-012022-09-11 Journal: Clinics in dermatology [Category] SARS, 치료기술, [키워드] affected Care coronavirus disease Coronavirus disease 2019 country COVID-19 Dermatology Health Health care health care workers health system Immunosuppressed Iran management Patient preventive measure preventive measures reaction required resource responses Spectrum virus [DOI] 10.1016/j.clindermatol.2020.12.009 PMC 바로가기 [Article Type] Article
Spectrum of neuroimaging findings in COVID-19COVID-19의 신경 영상 소견 스펙트럼Pictorial Review Published on 2021-01-012022-09-12 Journal: The British Journal of Radiology [Category] 진단, [키워드] Acute disseminated encephalomyelitis change China Complication COVID-19 Critical Critical illness Critically ill Disseminated encephalomyelitis Encephalopathy feature flare Hemorrhagic hospitalized COVID-19 hospitalized patient hospitalized patients hypertensive hypoxic include infections manifestation meningoencephalitis multiple sclerosis Neurological complications outbreak positive patient Spectrum spread to state stroke syndrome thrombosis Venous thrombosis Viral Virus Disease worldwide pandemic [DOI] 10.1259/bjr.20200812 PMC 바로가기 [Article Type] Pictorial Review
Peritonsillar Phlegmon: An Addition to the Spectrum of COVID-19Otolaryngology Published on 2020-12-292022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute respiratory syndrome caused coronavirus coronavirus disease cough COVID-19 Culture Epidemic etiology Fever Infection Inflammation knowledge less Lymphadenopathy morbidity and mortality pandemic Patient Peritonsillar peritonsillar phlegmon positive COVID-19 reported SARS-CoV-2 Shortness of breath shown Spectrum Symptoms the disease tonsillitis Wuhan, China [DOI] 10.7759/cureus.12369 PMC 바로가기 [Article Type] Otolaryngology
Excessive and Problematic Internet Use During the Coronavirus Disease 2019 School Closure: Comparison Between Japanese Youth With and Without Autism Spectrum DisorderPublic Health Published on 2020-12-172022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] age analyzed ASD autism Autism Spectrum Disorder children conducted Control control group coronavirus disease COVID-19 COVID-19 pandemic Digital media disorder higher risk individual Internet internet addiction Japan Japanese media pandemic Prevent Problematic internet use School significantly Spectrum Youth [DOI] 10.3389/fpubh.2020.609347 PMC 바로가기 [Article Type] Public Health
Culture-free genome-wide locus sequence typing (GLST) provides new perspectives on Trypanosoma cruzi dispersal and infection complexity무배양 게놈 전체 유전자좌 서열 유형 지정(GLST)은 트리파노소마 크루지 분산 및 감염 복잡성에 대한 새로운 관점을 제공합니다.Research Article Published on 2020-12-162022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] agarose gel alternate allele frequency amplification amplify analyzed approach biases capture capture method Cell Chagas disease Chain Reaction city clone Co-infection collected Complete complex correlation correlations Culture detect dispersal distribution DNA Ecuador epidemiological epidemiological surveillance evaluate Ex vivo flexible frequency distributions generate Genetic Genetic polymorphism Genetic variation Genome genomes genotyping hotspot identify infecting Infection infection source Infectious disease Infectious diseases information intestinal involved library limitation lineages locus marker metagenomic minimum parasite parasites pathogen Pathogenic microorganisms Perspective polymerase chain polymerase chain reaction polymerase chain reactions polymorphism powerful tool primer principle provide purification representing Research Result sequence Sequencing single-nucleotide Single-nucleotide polymorphisms SNP Spectrum Strains subsequent subset Surveillance target target pathogen Trypanosoma Trypanosoma cruzi vector Venezuela [DOI] 10.1371/journal.pgen.1009170 PMC 바로가기 [Article Type] Research Article