Elevated plasma levels of epithelial and endothelial cell markers in COVID-19 survivors with reduced lung diffusing capacity six months after hospital discharge병원 배출 6 개월 후 폐 확산 능력 감소 된 Covid-19 생존자에서 상피 및 내피 세포 마커의 혈장 수준 증가Observational Study Published on 2022-02-212022-09-01 Journal: Respiratory Research [Category] MERS, 바이오마커, 임상, 진단, [키워드] abnormality acute disease acute respiratory distress acute respiratory distress syndrome Adhesion Molecule angiopoietin ARDS carbon monoxide Cell Characteristics circulating clinical Clinical characteristics COVID-19 diffusing diffusing capacity discharge disease DLCO Dyspnoea E-selectin elevated endothelial Endothelial cell endothelial marker Endothelial markers epithelial Epithelial markers Follow-up hospital discharge Hospitalization hypertension independent risk factor independent risk factors individuals intercellular intercellular adhesion molecule leukocyte Level lung lung damage Lung function marker multivariate regression analysis observational study Occurrence Older Organizing pneumonia pathophysiology Patient patients plasma Plasma levels Pneumonia Post-COVID Prospective Protease inhibitor Protein Pulmonary embolism pulmonary embolisms reduced respiratory distress Result risk factor Risk factors selectin Sequelae severe COVID-19 severity Severity Score SLPI Smokers spirometry suffered supplementary material survivor Survivors syndrome [DOI] 10.1186/s12931-022-01955-5 PMC 바로가기 [Article Type] Observational Study
Treatment of COVID-19-associated ARDS with mesenchymal stromal cells: a multicenter randomized double-blind trialRandomized Controlled Trial Published on 2022-02-212022-10-04 Journal: Critical Care [Category] COVID19(2023년), MERS, SARS, 임상, [키워드] 95% CI acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome analyzed ANCOVA ARDS assigned baseline cause change Coronavirus-2 Course COVID-19-associated ARDS double-blind double-blind trial Efficacy eligibility enrolled fractional inspired oxygen French Good-manufacturing practice high mortality intravenous intravenous infusion modified intention-to-treat multicenter multicentre NaCl not differ oxygen PaO Patient Placebo placebo group placebo-controlled trial Randomized Randomly receive recipient recruited recruitment Result screened Serious Adverse Event Serious Adverse Events severe acute respiratory syndrome coronavirus-2 significantly stromal cell supplementary material syndrome the primary endpoint Treatment Trial UC-MSC UC-MSCs Umbilical cord-derived mesenchymal stromal cells [DOI] 10.1186/s13054-022-03930-4 PMC 바로가기 [Article Type] Randomized Controlled Trial
Comparative assessment of methods for short-term forecasts of COVID-19 hospital admissions in England at the local levelResearch Article Published on 2022-02-212022-10-28 Journal: BMC Medicine [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] Accuracy Admission Admissions baseline Care changed Comparative computation confirmed COVID-19 case Convolution COVID-19 COVID-19 pandemic COVID-19 patient distribution England Ensemble Epidemic facilitate Forecasting healthcare Healthcare demand hospital Hospital admission IMPROVE Infectious disease instance Linear regression model Local majority National Health Service NHS outbreak pandemic Predictive produced real-time resource resources Result robust scaled supplementary material trajectory Trust [DOI] 10.1186/s12916-022-02271-x PMC 바로가기 [Article Type] Research Article
Health-related quality of life of COVID-19 two and 12 months after intensive care unit admissionResearch Published on 2022-02-202022-10-28 Journal: Annals of Intensive Care [Category] COVID-19, [키워드] acute respiratory distress syndrome Admission Algorithm alteration body mass index COVID-19 discharge discharged Dyspnea enrolled Exercise capacity Factor French Gender health-related quality of life help ICU ICU admission identify intensive care interquartile range male mechanical ventilation Medical Research Council mMRC Mortality Multiple linear regression normalized Patient patients proportion Pulmonary function tests Quality of life rehabilitation rehabilitation facility reported Result returned risk Six-minute walk test smoking subsequent supplementary material Symptom transferred were assessed [DOI] 10.1186/s13613-022-00991-0 PMC 바로가기 [Article Type] Research
Clinical Frailty Scale (CFS) indicated frailty is associated with increased in-hospital and 30-day mortality in COVID-19 patients: a systematic review and meta-analysisResearch Published on 2022-02-202022-10-28 Journal: Annals of Intensive Care [Category] COVID-19, [키워드] 30-Day mortality 95% confidence interval Admission admitted to ICU calculated carried Ceiling of care CFS clinical Clinical frailty scale COVID-19 COVID-19 patient COVID-19 patients COVID-19 treatment guidelines database Efficacy eligible Evidence feasible frailty Future geriatric high risk higher risk Hospital Frailty Risk Score Hospital stay ICU ICU admission In-hospital index indicated intensive care International less management mean difference Meta-analysis Mortality MOST MPI Non-survivors outcome Patient protocol provide quantitative synthesis QUIPS tool random effect model Registered Result risk risk of bia risk stratification scale score searched supplementary material survivor systematic review was used [DOI] 10.1186/s13613-021-00977-4 PMC 바로가기 [Article Type] Research
How have governments supported citizens stranded abroad due to COVID-19 travel restrictions? A comparative analysis of the financial and health support in eleven countriesResearch Published on 2022-02-202022-10-28 Journal: BMC Infectious Diseases [Category] Coronavirus, COVID19(2023년), Fulltext, MERS, SARS, [키워드] Accessibility America analysed Analysis assist Canada coded communication content country COVID-19 COVID-19 pandemic COVID-19 situation effort evaluated examined Fiji France global public health Government guideline Health highlight information Japan measure mental health MOST New novel coronavirus disease pandemic provided raise Readability resources Result selected Singapore Spain subset supplementary material Support supported Travel United Kingdom United State USA Version was measured Web website [DOI] 10.1186/s12879-022-07155-2 PMC 바로가기 [Article Type] Research
Impaired detection of omicron by SARS-CoV-2 rapid antigen testsSARS-CoV-2 신속 항원 검사에 의한 오미크론 검출 장애Original Article Published on 2022-02-202022-09-10 Journal: Medical Microbiology and Immunology [Category] COVID19(2023년), MERS, SARS, 변종, 치료기술, 치료법, [키워드] analytical sensitivity Awareness B.1.1.529 B.1.617.2 Cell Cell culture collected comparable country Ct values detection rate diagnostic test driven by dropped evaluated examined globe highest Impaired Infection infection rate infection rates isolate Laboratory lateral flow limit of detection National nine nucleocapsid protein omicron pandemic PCR-negative PCR-positive point-of-care tests positive positive test result Predictive Predictive value ranged rapid antigen test Rapid antigen tests RAT RATs reduced required respiratory RNA copies RNA copy SARS-CoV-2 SARS-CoV-2 pandemic SARS-CoV-2 rapid antigen test sensitivity specificity specimen suggested supplementary material swab sample test results the SARS-CoV-2 variant virus load virus stock VoC [DOI] 10.1007/s00430-022-00730-z PMC 바로가기 [Article Type] Original Article
The impact of COVID-19 on the well-being, education and clinical practice of general practice trainees and trainers: a national cross-sectional studyResearch Published on 2022-02-192022-10-28 Journal: BMC Medical Education [Category] COVID-19, COVID19(2023년), Fulltext, MERS, SARS, [키워드] activities activity Care change changed Clinical practice COVID-19 COVID-19 pandemic cross-sectional Descriptive statistics education flexible General practice general practitioner Health care organization help Infectious disease measure medical education mental health MOST National pandemic participated performed Practice qualitative data Quantitative data question reducing reported required Result Stress Study design supplementary material Support telehealth thematic analysis was used Workplace learning [DOI] 10.1186/s12909-022-03174-4 PMC 바로가기 [Article Type] Research
PrEP Use, Sexual Behaviour, and PrEP Adherence Among Men who have Sex with Men Living in Wales Prior to and During the COVID-19 PandemicCovid-19 Pandemic 이전과 Covid-19 Pandemic 기간 동안 웨일즈에 사는 남성과 성관계를 가진 남성들 사이에서 준비, 성적 행동 및 준비 준수Original Paper Published on 2022-02-192022-09-10 Journal: AIDS and Behavior [Category] COVID19(2023년), Fulltext, MERS, SARS, 치료제, [키워드] 95%CI addition adherence Anal anal sex association CAS cascade clinics conducted contribute COVID-19 defined Disruption ecological examined followed by Health Health services HIV prevention implication individual measure Measures medication men outcomes participant PrEP receipt recruited reduction in Sex sexual Sexual behaviour supplementary material threat transmission of SARS-CoV-2 [DOI] 10.1007/s10461-022-03618-4 PMC 바로가기 [Article Type] Original Paper
Animated, video entertainment-education to improve vaccine confidence globally during the COVID-19 pandemic: an online randomized controlled experiment with 24,000 participantsRandomized Controlled Trial Published on 2022-02-192022-10-04 Journal: Trials [Category] COVID19(2023년), MERS, SARS, 임상, [키워드] Algorithms approach China clinical coronavirus disease COVID-19 COVID-19 vaccine Date distribution Effectiveness experiment global public health highlight Hope IMPROVE Intervention List experiment media Month outbreak parallel group participant Primary outcomes protocol randomization Randomized Randomized controlled trial RCT recruit regions Research Result Rrandomized controlled trial Secondary outcomes social media platforms supplementary material Support total sample size Trial USA vaccination Vaccine Vaccine acceptance Vaccine confidence Vaccine hesitancy yielding [DOI] 10.1186/s13063-022-06067-5 PMC 바로가기 [Article Type] Randomized Controlled Trial