IL-18 variant increases risk of enhanced HBV DNA replication in chronic hepatitisArticle Published on 2020-12-012023-06-12 Journal: Immunology letters [Category] B형 간염, [키워드] Chronic HBV infection DNA replication Interleukin-18 polymorphism susceptibility [DOI] 10.1016/j.imlet.2020.10.002
Covid-19-Associated Pulmonary Aspergillosis: The Other Side of the CoinReview Published on 2020-12-012022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] acute respiratory syndrome Anakinra approach Aryl hydrocarbon receptor Aspergillus Asymptomatic coin contribute coronavirus COVID-19 COVID-19 patients Critical disease dysregulated immune response fungal infections Host Immune homeostasis immune response immunomodulatory Infection mechanism morbidity and mortality occur Other pathway pulmonary reduce risk SARS-CoV-2 secondary bacterial Secondary infection side significantly susceptibility the disease therapeutic thymosin alpha 1 Treatment underlie viral infection [DOI] 10.3390/vaccines8040713 PMC 바로가기 [Article Type] Review
A multifactorial score including autophagy for prognosis and care of COVID-19 patientsCOVID-19 환자의 예후 및 치료를 위한 자가포식을 포함한 다인자 점수Article Published on 2020-12-012022-09-11 Journal: Autophagy [Category] MERS, SARS, 바이오마커, 유전자 메커니즘, 진단, [키워드] Abbreviation acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Antiviral Atg5 autophagy Beclin 1 BECN1 bronchitis Care cause concerning Control coronavirus COVID-19 COVID-19 outbreak COVID-19 patient COVID-19 severity Critical Critical care determine diarrhea effort EGR1 embryonic Endoplasmic reticulum epidemic diarrhea gastroenteritis Genetic Genome genomes growth highest hospital Host include Infectious Bronchitis Virus Intensive intensive care intensive care units joint less light chain membrane Middle East mouse hepatitis mouse hepatitis virus multifactorial non-structural protein Papain Papain-like protease Patient PEDV PLP2 polygenic score polymorphism processed Prognosis Protein referred to resource respiratory risk SARS-CoV-2 screening test Sequencing severe acute respiratory syndrome Coronavirus severe disease susceptibility TGEV the patient transmissible gastroenteritis virus treated virophagy virus [DOI] 10.1080/15548627.2020.1844433 PMC 바로가기 [Article Type] Article
Mechanisms and evidence of vertical transmission of infections in pregnancy including SARS-CoV-2sSARS-CoV-2를 포함한 임신 중 감염의 수직 전파 메커니즘 및 증거Review Published on 2020-12-012022-09-11 Journal: Prenatal diagnosis [Category] SARS, 치료기술, [키워드] ACE-2 amniotic Amniotic fluid Blood breast milk Chain Reaction Child clinical sample clinical samples co-expression concerning Consensus Cord blood COVID-19 cytoplasmic demonstrated determine diagnostic eight entry of SARS-CoV-2 Evidence explain histological examination Infection Inflammation Interaction involved lack membrane Migration mother Neonatal Neonatal COVID-19 pathogen performed Placenta placental placental barrier polymerase chain polymerase chain reaction Pregnancy pregnant women Prevent protective mechanism protective mechanisms question real-time polymerase chain reaction receptor reported SARS-CoV-2 SARS-CoV-2 IgM screened secretion susceptibility Swab tissue TMPRSS2 Transmission transplacental infection Umbilical cord umbilical cord blood Vascular Viral Viral particles with COVID-19 [DOI] 10.1002/pd.5765 PMC 바로가기 [Article Type] Review
COVID-19 in Elderly Adults: Clinical Features, Molecular Mechanisms, and Proposed StrategiesReview Article Published on 2020-12-012022-10-28 Journal: Aging and Disease [Category] COVID-19, [키워드] acute respiratory syndrome clinical clinical feature complications coronavirus Coronavirus disease 2019 COVID-19 COVID-19 patients death rate elderly Elderly patient feasibility molecular mechanism MOST pandemic Population populations problem SARS-CoV-2 Strategy susceptibility susceptible therapeutic strategy with COVID-19 [DOI] 10.14336/AD.2020.0903 PMC 바로가기 [Article Type] Review Article
Susceptibility of Raccoon Dogs for Experimental SARS-CoV-2 InfectionDispatch Published on 2020-12-012022-10-31 Journal: Emerging Infectious Diseases [Category] COVID-19, Fulltext, MERS, SARS, 조류인플루엔자, [키워드] 2019 novel coronavirus disease acute respiratory syndrome coronavirus coronavirus disease COVID-19 demonstrated dog had no Host Infection nasal Nyctereutes procyonoides occurred raccoon raccoon dog raccoon dogs Replication respiratory infections SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 susceptibility tissue lesion Transmission viruses zoonoses [DOI] 10.3201/eid2612.203733 PMC 바로가기 [Article Type] Dispatch
Association of HLA‐B22 serotype with SARS‐CoV ‐2 susceptibility in Hong Kong Chinese patientsBrief Communication Published on 2020-12-012022-10-31 Journal: HLA [Category] COVID-19, MERS, SARS, [키워드] association caused Chinese Chinese patient coronavirus coronavirus disease COVID‐19 COVID‐19 Critical Genotype global pandemic healthcare HLA Hong Kong Immunity Infection Infectious disease Pathogenesis positive SARS‐CoV‐2 SARS‐CoV‐2 infection SARS‐CoV‐2 serotype suggested susceptibility Vaccine development viral infections [DOI] 10.1111/tan.14135 PMC 바로가기 [Article Type] Brief Communication
In search of preventive strategies: novel high-CBD C annabis sativa extracts modulate ACE2 expression in COVID-19 gateway tissues예방 전략 찾기: 새로운 고 CBD C annabis sativa 추출물은 COVID-19 게이트웨이 조직에서 ACE2 발현을 조절합니다Research Paper Published on 2020-11-302022-08-31 Journal: Aging (Albany NY) [Category] SARS, 치료제, [키워드] ACE2 ACE2 expression ACE2 protein ACE2 receptor acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition airway Alter Analysis angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 Anti-inflammatory anti-inflammatory properties cannabidiol cannabis caused CBD coronavirus COVID-19 COVID-19 pandemic Critical curtail decrease disease disease spread disease susceptibility down-regulate Effect effective expressed gastrointestinal tract Gene Expression Health Canada help host cells human host Inflammation intestinal tissues kidney lung tissue medical cannabis modulate modulation nasal mucosa prevention strategies Protein receptor reduce mortality regulate required Research respiratory Safe SARS-CoV-2 SARS-CoV-2 entry SARS-CoV2 Serine serine protease serine protease TMPRSS2 severe acute respiratory syndrome Coronavirus Spread susceptibility testes therapeutic therapy tissue tissues TMPRSS2 Viral viral entry while working [DOI] 10.18632/aging.202225 PMC 바로가기 [Article Type] Research Paper
Natural versus Recombinant Viral Antigens in SARS-CoV-2 Serology: Challenges in Optimizing Laboratory Diagnosis of COVID-19SARS-CoV-2 혈청학에서 천연 바이러스 항원 대 재조합 바이러스 항원: COVID-19에 대한 실험실 진단 최적화의 과제Original Article Published on 2020-11-262022-09-10 Journal: Clinics [Category] MERS, SARS, 진단, 치료기술, 치료법, [키워드] anti-SARS-CoV-2 IgG antibodies anti-SARS-CoV-2 IgG antibody Antigen assays asymptomatic patient Brazil challenge choice commercialization control groups COVID-19 COVID-19 diagnosis COVID-19 negative criteria dependent on develop Diagnosis diagnosis of COVID-19 diagnostic ELISA estimation exhibited false-negative false-negatives False-positive false-positives fraction house IgG IgG antibodies in-house ELISA in-house ELISAs infected patient infected patients Infection information International Laboratory laboratory diagnosis natural nucleocapsid protein pandemic Patient performed public health emergency qPCR recombinant Recombinant nucleocapsid protein recombinant proteins SARS-CoV-2 SARS-CoV-2 Whole Viral Antigen sera serological test serology susceptibility the SARS-CoV-2 Viral Viral antigen viral antigens [DOI] 10.6061/clinics/2020/e2290 PMC 바로가기 [Article Type] Original Article
Gut Microbiota Status in COVID-19: An Unrecognized Player?Cellular and Infection Microbiology Published on 2020-11-262022-10-31 Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID-19, MERS, SARS, [키워드] Affect alteration Bacterial Cardiopulmonary cause characterized clinical condition clinical implication Comorbidities Comorbidity complex complications Consequences Course COVID-19 Deleterious develop example fatality gut microbiota gut-lung axis Health status healthy influence influenza A Interaction intestinal majority Microbiome microbiota microbiota manipulating microbiota-virus interactions Particle pathogenic mechanism pharmacological polypharmacy preventive therapeutic strategies progression reduce regimen Resilience risk risk factor SARS-CoV-2 SARS-COV-2 infection SARS-CoV2 infection severity status subject surface molecule susceptibility target the SARS-CoV-2 virus Treatment understanding variety Vascular viral infections virulence viruses [DOI] 10.3389/fcimb.2020.576551 PMC 바로가기 [Article Type] Cellular and Infection Microbiology