The Cell Tropism of Porcine Respiratory Coronavirus for Airway Epithelial Cells Is Determined by the Expression of Porcine Aminopeptidase NArticle Published on 2020-10-232022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] abundantly expressed air–liquid interface air–liquid interface culture airway airway epithelial cell aminopeptidase Analysis apical membrane APN applied bronchial cell bronchial epithelial cell Cell cell tropism cells cellular receptor complex Coronaviruses Culture determined by disease domain epithelial cell expected Express expression immortalized cell lines in vitro infect Infection mild respiratory non-mucus-producing occurred porcine aminopeptidase N porcine respiratory coronavirus reported respiratory Respiratory Coronavirus respiratory tract susceptibility susceptible target the cell tracheal tropism virus virus entry [DOI] 10.3390/v12111211 PMC 바로가기 [Article Type] Article
Human genetic factors associated with susceptibility to SARS-CoV-2 infection and COVID-19 disease severityReview Published on 2020-10-222022-10-31 Journal: Human Genomics [Category] COVID-19, MERS, SARS, [키워드] accumulate acute respiratory syndrome Allelic variation assist association Asymptomatic binding Biomedical research candidate gene caused Cell changed Characteristics children China clinical disease clinical manifestation Clinical outcome component contribute coronavirus coronavirus disease COVID-19 COVID-19 disease severity COVID-19 severity death determinant disease course disease severity effective vaccine effort example explain Factor Genetic genetic determinant Genetic predisposition Genetic variant genetics Genotype help high risk host genetics Human immune response immunization include individual infect infected case Infection initial knowledge male mechanism morbidity and mortality Novel coronavirus observation Older pandemic Patient Polymorphisms populations reported Research Respiratory failure resulting risk Safe SARS-CoV-2 SARS-COV-2 infection severe pneumonia severity severity of COVID-19 Stage Stratification surface receptor susceptibility symptomatic infection synchronization TLR7 variant virus Wuhan X chromosome [DOI] 10.1186/s40246-020-00290-4 PMC 바로가기 [Article Type] Review
A new domestic cat genome assembly based on long sequence reads empowers feline genomic medicine and identifies a novel gene for dwarfism긴 서열 판독을 기반으로 한 새로운 국내 고양이 게놈 어셈블리는 고양이 게놈 의학에 힘을 실어주고 왜소증에 대한 새로운 유전자를 식별합니다Research Article Published on 2020-10-222022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] aligned allele analyses Analysis Author Biology Biosynthesis Cancer candidate cats chromosome complex correlated Deleterious disease distribution duplication dwarfism expansion facilitate FBXW7 Felis framework Genome genome assembly genomic genomic variation Glucose Health help Households human gene Human genetics humans identify Impact IMPROVE information involved landscape lead Lineage lymphoma Mutation mutations nucleotide patients phenotype Phenotypes predicted rare diseases reference genome resource screened sequence sequence variation significantly Single nucleotide variant single nucleotide variants SNV SNVs Structural variant structural variants susceptibility SVs Tumor tumor suppressor UGDH USA utility variant Variation whole genome sequence [DOI] 10.1371/journal.pgen.1008926 PMC 바로가기 [Article Type] Research Article
Association Between Depression, Health Beliefs, and Face Mask Use During the COVID-19 PandemicPsychiatry Published on 2020-10-222022-10-31 Journal: Frontiers in Psychiatry [Category] COVID-19, [키워드] 2019 novel coronavirus 95%CI association convenience sampling COVID-19 COVID-19 outbreak COVID-19 pandemic demographic characteristics Depression depressive symptom face Face mask Future General population Health Health Belief Model health information highlight Hong Kong ideation identify increases in independent variable information knowledge less Logistic regression Mask morbidity pandemic PHQ-9 Probability protective factor Psychiatric recruit respondent reuse Self-efficacy severity social media platform subpopulations susceptibility was used wearing mask [DOI] 10.3389/fpsyt.2020.571179 PMC 바로가기 [Article Type] Psychiatry
Patient Perceptions about Professional Dental Services during the COVID-19 PandemicCOVID-19 Published on 2020-10-212022-10-31 Journal: JDR Clinical and Translational Research [Category] COVID-19, MERS, SARS, [키워드] Access to care Adults age agency Care clinical practice guidelines community dentistry condition COVID-19 cross-sectional demographics dental dental health survey dental public health event help high risk hygiene include Infection information Last over pandemic pandemic progresses Patient patients Perceived risk Perception populations positive professional provide Psychosocial factors public health receiving reported risk routine care Safe service study participant survey susceptibility susceptible variable [DOI] 10.1177/2380084420969116 PMC 바로가기 [Article Type] COVID-19
Susceptibility of swine cells and domestic pigs to SARS-CoV-2Research Article Published on 2020-10-202022-10-31 Journal: Emerging Microbes & Infections [Category] COVID-19, MERS, SARS, [키워드] animal model antibody carrier Cell cell line cell lines Clinical signs Consequences coronavirus COVID-19 cytopathic effects develop effective Efficacy Evidence global pandemic Infection infection models marker morbidity Mortality naïve pig PIGS replicate responses SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pathogenesis susceptibility susceptible swine Transmission unlikely Vaccine viral replication zoonotic disease [DOI] 10.1080/22221751.2020.1831405 PMC 바로가기 [Article Type] Research Article
Risk perception related to COVID-19 among the Iranian general population: an application of the extended parallel process modelResearch Article Published on 2020-10-192022-10-28 Journal: BMC Public Health [Category] COVID-19, MERS, SARS, [키워드] accompany age analysis of variance ANOVA avoidance Behavior response component conducted contribute Coronavirus disease 2019 COVID-19 COVID-19 outbreak cross-sectional Danger control demographic factor Descriptive statistics determinant Efficacy Extended Extended parallel process model Fear control female global public health group indicated individual information Instagram Iran men Model novel coronavirus disease Older pandemic participant participated platform Process questionnaire recruited response responses Result Risk perception Self-efficacy significant difference significantly higher susceptibility t-test targeted intervention the disease was used were used WhatsApp women [DOI] 10.1186/s12889-020-09681-7 PMC 바로가기 [Article Type] Research Article
Comparison of nonhuman primates identified the suitable model for COVID-19Article Published on 2020-10-192022-10-04 Journal: Signal Transduction and Targeted Therapy [Category] MERS, SARS, 유전자 메커니즘, 진단, [키워드] acute respiratory syndrome blood sample body temperature Callithrix characterized Chest coronavirus COVID-19 Experimental models of disease expression Genome identification Infection Inflammatory cytokine New World monkey NHP Old World monkey pathological change SARS-CoV-2 susceptibility Swab These data tissue tissues Vaccines [DOI] 10.1038/s41392-020-00269-6 PMC 바로가기 [Article Type] Article
Interferons and viruses induce a novel truncated ACE2 isoform and not the full-length SARS-CoV-2 receptor Research Published on 2020-10-192022-10-05 Journal: Nature Genetics [Category] SARS, 유전자 메커니즘, [키워드] ACE2 ACE2 expression acute respiratory syndrome amino acids angiotensin-converting enzyme 2 atlas binding cause cellular entry Co-infection condition coronavirus COVID-19 expression full-length SARS-CoV-2 independent induce Infection Inflammatory interferon-stimulated gene ISG isoform lack outcomes promote receptor SARS-CoV-2 Spike protein susceptibility target cells the SARS-CoV-2 transcriptionally Tumor tumor microenvironment unlikely Variability virus [DOI] 10.1038/s41588-020-00731-9 [Article Type] Research
Sex differences in clinical phenotype and transitions of care among individuals dying of COVID-19 in ItalyResearch Published on 2020-10-162022-10-28 Journal: Biology of Sex Differences [Category] COVID-19, MERS, SARS, [키워드] 95% CI Acute kidney injury acute respiratory illness Admission Analysis analyzed Autoimmune disease both sexes Care Characteristics Chronic kidney disease chronic obstructive clinical clinical feature clinical manifestation clinical phenotype Comorbidities coronavirus disease COVID-19 COVID-19-related death death Deceased Dementia different clinical manifestation disease explain feature Fever Hospitalized identify identifying in-hospital complications individual individuals with COVID-19 ischemic heart disease Italy laboratory-confirmed SARS-CoV-2 infection Male sex men Multimorbidity Nasopharyngeal swab occurred Older outbreak outcome Prevalence progression pulmonary disease Result Retrospective analysis Sex Sex difference susceptibility therapy Transition of care was performed with COVID-19 women [DOI] 10.1186/s13293-020-00334-3 PMC 바로가기 [Article Type] Research