Does Circulating Antibody Play a Role in the Protection of Piglets against Porcine Epidemic Diarrhea Virus?Research Article Published on 2016-04-062022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, [키워드] 24 hour Administered administration ameliorated Analysis antibody Antibody Response antibody transfer assigned body temperature circulating circulating antibody Clinical signs collected colostrum contribute contributed demonstrated Effect epidemic diarrhea evaluated experiment faster fecal fecal samples group growth IgA IgG Infection infections inoculated intraperitoneally naïve Neonatal PCR PEDV protection provided Randomized real-time reverse transcriptase remained returned role secretory IgA serum antibody suggested Survivability survival TCID tested Treatment virus virus-neutralizing antibody [DOI] 10.1371/journal.pone.0153041 PMC 바로가기 [Article Type] Research Article
Experimental feline enteric coronavirus infection reveals an aberrant infection pattern and shedding of mutants with impaired infectivity in enterocyte culturesArticle Published on 2016-01-292022-10-29 Journal: Scientific Reports [Category] Coronavirus, MERS, [키워드] abnormality absence affected antibody blood cell CD8 Clinical sign Clinical signs coronavirus Coronavirus infection Culture Feline infectious peritonitis Hypothesis Immune cell immunological infect Infection Infectious virus intestinal investigated less leukocyte Mild mutant mutated Mutation mutations neutralising antibody not different occurred raise regulatory T cells Replication reveal SPF these cell Viraemia viral genome Virological virus [DOI] 10.1038/srep20022 PMC 바로가기 [Article Type] Article
Experimental infection of a US spike-insertion deletion porcine epidemic diarrhea virus in conventional nursing piglets and cross-protection to the original US PEDV infectionResearch Article Published on 2015-11-202022-10-28 Journal: Veterinary Research [Category] Coronavirus, MERS, [키워드] anorexia Antigen Clinical signs cross-protection diarrhea epidemic diarrhea Factor fecal Health Infection inoculated intestinal lactation less morbidity Mortality Multiple studies negative controls PEDV positive provided RNA severity strain subset virulence virulent virus watery [DOI] 10.1186/s13567-015-0278-9 PMC 바로가기 [Article Type] Research Article
Effect of Porcine Epidemic Diarrhea Virus Infectious Doses on Infection Outcomes in Naïve Conventional Neonatal and Weaned PigsResearch Article Published on 2015-10-062022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] Antibody Response caused cell culture medium Clinical signs condition Conventional cycle threshold determine Effect epidemic diarrhea group Histopathology immunohistochemistry Infection infectious dose infectious titer information inoculated medium naïve Neonatal Neonate observation PCR PEDV pig polymerase chain significantly lower Spread TCID the United State virulent virus [DOI] 10.1371/journal.pone.0139266 PMC 바로가기 [Article Type] Research Article
Canine Enteric Coronaviruses: Emerging Viral Pathogens with Distinct Recombinant Spike ProteinsReview Published on 2014-08-222022-10-28 Journal: Viruses [Category] Coronavirus, MERS, [키워드] addition Canine coronavirus caused Clinical signs coronavirus disease severity dissemination domain enteric Evidence Host increase in infecting Infection Infectious disease Mild NTDs occur recombinant Recombination serotype spike spike gene Spike protein Strains variant viral pathogenesis while [DOI] 10.3390/v6083363 PMC 바로가기 [Article Type] Review
The tree shrew provides a useful alternative model for the study of influenza H1N1 virusResearch Published on 2013-04-102023-06-07 Journal: Virology Journal [Category] 신종인플루엔자, [키워드] Clinical signs Influenza H1N1 virus pathological changes receptors Replication Tree shew [DOI] 10.1186/1743-422X-10-111 PMC 바로가기 [Article Type] Research
A Recombinant Avian Infectious Bronchitis Virus Expressing a Heterologous Spike Gene Belonging to the 4/91 SerotypeResearch Article Published on 2011-08-302022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] absence backbone Belonging Clinical sign Clinical signs defined different ectodomain effective expressing Genetic Heterologous homologous IBV Infected M41 observation pathogenic pathogenicity qRT-PCR recombinant removed RNA S gene serotype shown spike the S protein the spike protein Trachea Vaccines virus wild type [DOI] 10.1371/journal.pone.0024352 PMC 바로가기 [Article Type] Research Article