hospitalized COVID-19 patients – Page 13 – Communicable Diseases Research

Design and rationale of the colchicine/statin for the prevention of COVID-19 complications (COLSTAT) trial

Randomized Controlled Trial

Published on 2021-11-012022-10-05
Journal: Contemporary clinical trials [Category] SARS, 신약개발, 임상,

Assessment of antiphospholipid antibodies and calprotectin as biomarkers for discriminating mild from severe COVID-19

경증에서 중증 COVID-19를 구별하기 위한 바이오마커로서의 항인지질 항체 및 칼프로텍틴의 평가

Article

Published on 2021-11-012022-09-11
Journal: Journal of Clinical Laboratory Analysis [Category] MERS, SARS, 바이오마커, 진단, 치료기술,

[키워드] acute respiratory distress acute respiratory distress syndrome antibodies antibody anticardiolipin antibodies anticardiolipin antibody antiphospholipid antibodies assessment association Biomarker C-reactive protein C-reactive protein (CRP calprotectin CD4 clinically coronavirus coronavirus disease correlation COVID-19 COVID-19 patient COVID-19 patients CRP CRP level CRP levels detectable Detection limit elevated ELISA enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay evaluated ferritin groups healthy control healthy controls help highest Hospitalization hospitalized COVID-19 patient hospitalized COVID-19 patients IgM immunoassay IMPROVE Inflammatory laboratory parameter lymphocyte Lymphocyte count management Mild moderate multiplex negative correlation neutrophil Neutrophil-to-lymphocyte ratio no significant differences not differ outcome oxygenation status parameter pathway peak levels Prevalence procalcitonin proportion respiratory distress Respiratory distress syndrome sera severe COVID-19 severe group severity significant differences significantly significantly higher syndrome T cells two group two groups were measured
[DOI] 10.1002/jcla.24004 PMC 바로가기 [Article Type] Article

Plasma zinc status and hyperinflammatory syndrome in hospitalized COVID-19 patients: An observational study

Observational Study

Published on 2021-11-012022-10-05
Journal: International immunopharmacology [Category] SARS, 임상,

[키워드] 95% CI acute respiratory distress antiviral response association Biomarker cHIS. Clinical outcome Cohort Complication Concentration conducted control group correlated COVID-19 COVID-19 patient CRS cytokine releasing syndrome deficiency diagnosed with COVID-19 early stage eligible patient Hospital stay hospitalized COVID-19 hospitalized COVID-19 patient hospitalized COVID-19 patients Hyperinflammatory syndrome Infection Inflammation interquartile range IQR majority median median age morbidity Mortality Non-COVID-19 outcome outcomes Patient PCR-confirmed plasma zinc concentration Prevalence Prognostic marker retrospective risk robust SARS-CoV-2 severe SARS-CoV-2 significantly single-center Support syndrome tested the disease university hospital Zinc
[DOI] 10.1016/j.intimp.2021.108163 PMC 바로가기 [Article Type] Observational Study

The Activin/FLRG Pathway Associates with Poor COVID-19 Outcomes in Hospitalized Patients

Activin/FLRG Pathway는 입원 환자의 COVID-19 결과가 좋지 않습니다.

Clinical Trial

Published on 2021-11-012022-09-10
Journal: Molecular and Cellular Biology [Category] MERS, SARS, 비임상, 임상, 진단,

[키워드] activate activin activin A activin B acute respiratory disease acute respiratory disease syndrome all-cause mortality antibody ARDS Associate blockade breath characterized Comorbidities COVID-19 COVID-19 patient COVID-19 patients cytokine Cytokine storm Cytokines decrease demonstrated develop elevated evaluate Evidence examined FLRG FSTL3 Hospital admission hospitalized COVID-19 patients increase in indicate indicated induce inhibitor lung viral load mechanical ventilation NF-κB NF-κB pathway outcome pathology Poor risk SARS-CoV-2 SARS-COV-2 infection Signaling subset syndrome the disease those with comorbidities treating COVID-19 patient Viral Viral load
[DOI] 10.1128/MCB.00467-21 PMC 바로가기 [Article Type] Clinical Trial

Tocilizumab administration for the treatment of hospitalized patients with COVID-19: A systematic review and meta-analysis

코로나19 입원환자 치료를 위한 토실리주맙 투여: 체계적 고찰 및 메타분석

Review

Published on 2021-11-012022-09-12
Journal: Respirology (Carlton, Vic.) [Category] MERS, SARS, 진단,

[키워드] 95% CI administration Admission benefit clinically composite endpoint coronavirus coronavirus disease Corticosteroids COVID-19 Cytokine storm Effectiveness Efficacy evaluate Hospitalization hospitalized COVID-19 patients hospitalized patient ICU improved mortality IMV intensive care Invasive mechanical ventilation lower mortality management Meta-analysis Mortality nine non-ICU patient non-ICU patients observational studies observational study outcome Patient patients Randomized controlled trial RCT RCTs receiving reduction reduction in risk SARS-CoV-2 searched Secondary objective subgroup systematic review systemic corticosteroids Tocilizumab Treatment was reduced
[DOI] 10.1111/resp.14152 PMC 바로가기 [Article Type] Review

Special report of the RSNA COVID-19 task force: systematic review of outcomes associated with COVID-19 neuroimaging findings in hospitalized patients

RSNA COVID-19 태스크포스 특별 보고서: 입원 환자의 COVID-19 신경영상 소견과 관련된 결과에 대한 체계적인 검토

Systematic Review

Published on 2021-11-012022-09-12
Journal: The British Journal of Radiology [Category] 진단,

[키워드] Acuity Acute disseminated encephalomyelitis adult COVID-19 patients advance age all-cause mortality Analysis articles COVID-19 COVID-19 patient demographics Disseminated encephalomyelitis element feature followed by hemorrhage high mortality rate highest hospitalized COVID-19 patient hospitalized COVID-19 patients hospitalized patient hospitalized patients ICH intracranial hemorrhage Ischemic Stroke leptomeningeal leukoencephalopathy literature review Mortality Necrosis Neurological symptom Neurological symptoms outcome outcomes Patient performed Prognostic marker reported Specific stroke systematic review unique were recorded with COVID-19
[DOI] 10.1259/bjr.20210149 PMC 바로가기 [Article Type] Systematic Review

Special report of the RSNA COVID-19 task force: systematic review of outcomes associated with COVID-19 neuroimaging findings in hospitalized patients

Systematic Review

Published on 2021-11-012022-10-27
Journal: The British Journal of Radiology [Category] COVID-19,

Elevated cytokines and chemokines in peripheral blood of patients with SARS-CoV-2 pneumonia treated with high-titer convalescent plasma

고역가 회복기 혈장으로 치료한 SARS-CoV-2 폐렴 환자의 말초혈액 내 사이토카인 및 케모카인 상승

Research Article

Published on 2021-10-292022-09-12
Journal: PLoS Pathogens [Category] MERS, SARS, 진단,

[키워드] acute respiratory distress acute respiratory distress syndrome addition administration Blood caused chemokine chemokines Clinical course clinical trial Cohort Concentration conducted contribute convalescent convalescent plasma Convalescent plasma therapy correlated Course COVID-19 COVID-19 pneumonia CRP cytokine Cytokine storm syndrome Cytokines Day Deterioration Disease progression Donor donors Efficacy elevated Elevation elevations evaluate fatality foundation healthy controls Hospitalization Hospitalized hospitalized COVID-19 hospitalized COVID-19 patient hospitalized COVID-19 patients IIa immune immune activation immune response IMPROVE increase in Inflammatory Inflammatory cytokines infusion institution Lung pathology mechanical ventilation MIP-1α MIP-1β Neutralizing antibodies neutralizing antibody Neutralizing titer observation outcomes pandemic Patient patients patients hospitalized patients with SARS-CoV-2 Peripheral blood phase plasma plasma sample plasma samples Pneumonia Potential biomarker potential biomarkers receive recipient recipients respiratory distress Respiratory distress syndrome resulting SARS-CoV-2 coronavirus SARS-COV-2 infection SARS-CoV-2 virus significant difference syndrome the cytokine storm the disease the patient the SARS-CoV-2 virus the timing track transfer treat treated Treatment unique virus while with COVID-19
[DOI] 10.1371/journal.ppat.1010025 PMC 바로가기 [Article Type] Research Article

Divergent COVID-19 Disease Trajectories Predicted by a DAMP-Centered Immune Network Model

DAMP 중심 면역 네트워크 모델이 예측하는 다양한 COVID-19 질병 궤적

Immunology

Published on 2021-10-282022-09-12
Journal: Frontiers in Immunology [Category] MERS, SARS, 진단,

Occurrence, Fate, Effects, and Risks of Dexamethasone: Ecological Implications Post-COVID-19

Review

Published on 2021-10-272022-10-29
Journal: International Journal of Environmental Research an [Category] COVID-19, SARS,