How to Face the Advent of SARS-CoV-2 Vaccination in IBD Patients: Another Task for GastroenterologistsPerspective Published on 2021-03-122022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] acceptance administration advent available data chronic condition clinical experience COVID-19 COVID-19 pandemic develop dissect distribution effective Efficacy effort face Factor Gastroenterologist highest IBD immune system implication infections Inflammatory bowel disease pandemic Patient patients raised SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccination severity significantly the SARS-CoV-2 therapy Topic vaccination Vaccine Vaccine development Vaccines [DOI] 10.3390/vaccines9030248 PMC 바로가기 [Article Type] Perspective
The JAK Inhibitor Tofacitinib Rescues Intestinal Barrier Defects Caused by Disrupted Epithelial-macrophage InteractionsOriginal Article Published on 2021-03-102024-09-04 Journal: Journal of Crohn's and Colitis [Category] 대상포진, [키워드] epithelial cells IBD Jak-STAT Macrophage permeability TCPTP tight junction [DOI] 10.1093/ecco-jcc/jjaa182 PMC 바로가기 [Article Type] Original Article
Intestinal Receptor of SARS-CoV-2 in Inflamed IBD Tissue Seems Downregulated by HNF4A in Ileum and Upregulated by Interferon Regulating Factors in Colon염증이 있는 IBD 조직에서 SARS-CoV-2의 장 수용체는 회장에서 HNF4A에 의해 하향 조절되고 결장에서 인터페론 조절 인자에 의해 상향 조절되는 것으로 보입니다Article Published on 2021-03-052022-09-11 Journal: Journal of Crohn's & colitis [Category] SARS, 유전자 메커니즘, [키워드] ACE2 ACE2 expression Alter analysed Analysis anti-TNF biopsy bowel Co-expression analysis collected Colon colonic Control COVID-19 Crohn's disease Cytokines Differential gene expression disease dysregulation entry mechanisms epithelial Factor HNF4A IBD IBD susceptibility gene ileal ileum Immunosuppressed inflamed CD ileum Inflammation Inflammatory Inflammatory bowel disease inflammatory bowel diseases inflammatory stimuli interferon intestinal intestinal inflammation intestine investigated Microarray Microarrays mucosal Necrosis network Organoid organoids Patient patients pro-inflammatory cytokine pro-inflammatory cytokines processed Prognosis regulated Regulating Regulation responders restored risk factor RNA sequencing SARS-CoV-2 SARS-COV-2 infection Sequencing sequencing data shown significantly Single Cell single-cell therapy tissue TMPRSS2 transcriptomics ulcerative colitis upregulated upstream [DOI] 10.1093/ecco-jcc/jjaa185 PMC 바로가기 [Article Type] Article
Impact of COVID-19 outbreak on the care of patients with inflammatory bowel disease: A comparison before and after the outbreak in South ChinaObservational Study Published on 2021-03-012022-10-05 Journal: Journal of gastroenterology and hepatology [Category] 임상, [키워드] bowel Care China comparable COVID-19 COVID-19 outbreak decrease Elective surgery Health Health care health-care IBD immunomodulator Impact Inflammatory Inflammatory bowel disease investigated median medication outbreak Patient patients performed physician questionnaire significantly higher South supported the mean [DOI] 10.1111/jgh.15205 PMC 바로가기 [Article Type] Observational Study
Humoral response to COVID-19 infection in immunosuppressed patients with inflammatory bowel disease염증성 장질환이 있는 면역억제 환자의 코로나19 감염에 대한 체액 반응Case Reports Published on 2021-03-012022-09-11 Journal: European journal of gastroenterology & hepatology [Category] SARS, 바이오마커, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Admission advanced age Anosmia antibody Antibody testing cardiovascular diseases clinical manifestation Comorbidity coronavirus Course COVID-19 COVID-19 infection described determined by diabetes diarrhea disease severity dysgeusia hospital Humoral response hypertension IBD ICU immune response immunosuppressed patient Immunosuppression immunosuppressive Immunosuppressive medication immunosuppressive therapy Immunosuppressive treatment Indicator Infection Inflammatory bowel disease initial symptoms management older patient older patients Patient patients patients with COVID-19 PCR Pyrexia respiratory restart SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 antibody testing severe acute respiratory syndrome Coronavirus symptoms of COVID-19 tested therapy virus-specific antibodies [DOI] 10.1097/MEG.0000000000002094 PMC 바로가기 [Article Type] Case Reports
COVID-19 in IBD: The experience of a single tertiary IBD centerIBD의 COVID-19: 단일 3차 IBD 센터의 경험Observational Study Published on 2021-03-012022-09-12 Journal: Digestive and liver disease : official journal of [Category] MERS, SARS, 임상, 진단, [키워드] Administered affected analyzed Biological Biological treatment country COVID-*19 COVID-19 died disease General population Hospitalization IBD IBD. Immunosuppressant incidence incidence of COVID-19 Infection Inflammatory bowel disease Italy large cohort majority MOST Patient patients patients treated positive questionnaire required risk factor severity of COVID-19 Symptom tested therapy Treatment Two patient worsening [DOI] 10.1016/j.dld.2020.12.012 PMC 바로가기 [Article Type] Observational Study
Impact of the COVID-19 outbreak and the serum prevalence of SARS-CoV-2 antibodies in patients with inflammatory bowel disease treated with biologic drugs생물의약품으로 치료받는 염증성 장질환 환자에서 코로나19 발병과 SARS-CoV-2 항체의 혈청 유병률의 영향Article Published on 2021-03-012022-09-12 Journal: Digestive and liver disease : official journal of [Category] SARS, 진단, [키워드] Administered age biologic Biologic therapy Charlson Comorbidity Index children Clinical data close contact co-morbidities COVID-19 COVID-19 outbreak disease drug drugs enrolled Hospitalization Hospitalized IBD IgG Impact Infection Inflammatory bowel disease investigated Patient positive Prevalence receiving reported respiratory symptoms risk risk factor SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 antibody testing SARS-CoV-2 positive patients serum Symptom the SARS-CoV-2 therapy treated Treatment Two patient ulcerative colitis viral infections was collected [DOI] 10.1016/j.dld.2020.12.120 PMC 바로가기 [Article Type] Article
COVID-19 and inflammatory bowel disease: A pathophysiological assessment코로나19와 염증성 장질환: 병태생리학적 평가Review Published on 2021-03-012022-09-12 Journal: Biomedicine & pharmacotherapy = Biomédecine & phar [Category] SARS, 진단, [키워드] acute respiratory distress B(0)AT1 bowel caused COVID-19 COVID-19 patient Cytokine release syndrome develop dysregulated gastrointestinal symptoms global pandemic IBD immune immune response Immunity Inflammatory Inflammatory bowel disease Interaction majority management mild symptoms multiple organ failure pathogenesis of COVID-19 pathophysiological Patient Pneumonia question SARS-CoV-2 SARS-COV-2 infection secondary hemophagocytic lymphohistiocytosis syndrome therapy [DOI] 10.1016/j.biopha.2021.111233 PMC 바로가기 [Article Type] Review
SARS-CoV-2 and the Gastrointestinal Tract in ChildrenPediatrics Published on 2021-02-222022-10-31 Journal: Frontiers in Pediatrics [Category] COVID-19, [키워드] abdominal pain abundantly expressed ACE-2 acute respiratory syndrome angiotensin-converting enzyme-2 anorexia Appendicitis Atypical Care caused Cell change changes in children Clinical practice coronavirus Coronavirus disease 2019 COVID-19 COVID-19 pandemic diagnostic procedures diarrhea disorder enterocytes explain gastroenterology Gastrointestinal gastrointestinal symptoms Gut Health Service Healthcare provision homeostasis IBD include Inflammation Inflammatory bowel disease intestinal lung cells management manifestation mechanism mimicking mucosal nausea pediatric gastroenterology presenting symptom raised receptor reported Respiratory disease risk Safe SARS-CoV-2 the disease tract vomiting [DOI] 10.3389/fped.2021.617980 PMC 바로가기 [Article Type] Pediatrics
COVID-19—from mucosal immunology to IBD patientsCOVID-19—점막 면역학에서 IBD 환자까지Review Published on 2021-02-192022-09-10 Journal: Mucosal Immunology [Category] MERS, SARS, 바이오마커, [키워드] Affect characterized Clinical management COVID-19 digestive system disease epithelial cells IBD immune responses immunology implication infect infected individuals Infection Inflammatory bowel disease intestinal intestinal epithelial cells mucosal outcome Patient Pneumonia SARS-CoV-2 SARS-CoV-2 infected individuals SARS-COV-2 infection systemic inflammatory tropism of SARS-CoV-2 Viral viral infections [DOI] 10.1038/s41385-021-00384-9 PMC 바로가기 [Article Type] Review