Can Nuclear Imaging of Activated Macrophages with Folic Acid-Based Radiotracers Serve as a Prognostic Means to Identify COVID-19 Patients at Risk?Opinion Published on 2020-09-092022-10-28 Journal: Pharmaceuticals [Category] COVID-19, [키워드] activated activated macrophage acute respiratory distress applied ARDS bind Can Cancer clinical trials complications Coronavirus infections COVID-19 COVID-19 patient Cytokine storm Cytokines develop disease expressed Exuberant folate receptor-beta (FRβ) folate-based 18F-PET tracer host responses IL-1β IL-6 imaging imaging biomarker immune Inflammation inflammatory conditions Interstitial lung disease involved life-threatening Lung diseases Macrophage macrophages modulating multicenter nuclear outcome patients patients with COVID-19 positron emission tomography (PET) radiotracer risk severe disease progression Support syndrome tested therapy TNFα Trial [DOI] 10.3390/ph13090238 PMC 바로가기 [Article Type] Opinion
The Model for Early COvid-19 Recognition (MECOR) Score: A Proof-of-Concept for a Simple and Low-Cost Tool to Recognize a Possible Viral Etiology in Community-Acquired Pneumonia Patients during COVID-19 OutbreakArticle Published on 2020-08-212022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] addition affected AUROC blood cell count case-control study chest pain Cohort community-acquired pneumonia coronavirus cough COVID-19 COVID-19 patient cut-off Diagnosis diagnostic disease Dyspnea Effectiveness eosinophils evaluated examined excluded Fever immunosuppressants index Interstitial lung disease Lymphocytes Model modify Monocytes multivariate model nasopharyngeal swabs Neutrophils P -value parameter Patient patients treated peripheral blood cell Platelets Pneumonia Probability Prospective Study Recognition reduction in respiratory retrospective SARS-CoV-2 score selected sensitivity simple specificity Steroids Triage validation cohort White blood cell [DOI] 10.3390/diagnostics10090619 PMC 바로가기 [Article Type] Article
Proceedings from the 2 nd Next Gen Therapies for Systemic Juvenile Idiopathic Arthritis and Macrophage Activation Syndrome symposium held on October 3-4, 2019article Published on 2020-07-152024-09-02 Journal: Pediatric Rheumatology Online Journal [Category] 대상포진, [키워드] Alveolar macrophages hemophagocytic lymphohistiocytosis Interferonopathy Interstitial lung disease macrophage activation syndrome Pulmonary alveolar proteinosis Systemic juvenile idiopathic arthritis [DOI] 10.1186/s12969-020-00444-7 PMC 바로가기 [Article Type] article
Proactive Prophylaxis With Azithromycin and HydroxyChloroquine in Hospitalised Patients With COVID-19 (ProPAC-COVID): A structured summary of a study protocol for a randomised controlled trialLetter Published on 2020-06-102022-10-29 Journal: Trials [Category] Coronavirus, SARS, [키워드] 1:1 Administered age antibiotic antiviral efficacy Asthma Azithromycin Beta blocker blinded block calcium cardiovascular change changed chronic clinical combination therapy Control control group coordinator COPD COVID-19 COVID-19 test Day days alive death derivative Diagnosis Direct Current discharged disorder dissemination double-blind study ECG element ergot alkaloid expected Final FiO2 generate Glucose glucose-6-phosphate dehydrogenase deficiency guide hearing loss hematological hospital hospitalisation Hospitalization hospitals Hydroxychloroquine hypersensitivity impede Inclusion Informed consent intensive care Interstitial lung disease Intervention intervention group invasive ventilation investigated investigator Liver disease lung maculopathy medication mental illness modulation myasthenia gravis negative pregnancy test network Neurogenic neurological number objective offered outcome parallel group participant Patient patients with COVID-19 Placebo pregnant Primary outcome problem protocol psoriasis pulmonary QTc QTc interval randomisation randomised randomised controlled trial receive recruited recruitment reduce Registered reported respiratory infections retinopathy risk Sample size sequence significantly Sponsor Standard standard care standard treatment status Stratification Study protocol the patient therapy treated Treatment Trial Visual field website women [DOI] 10.1186/s13063-020-04409-9 PMC 바로가기 [Article Type] Letter
Efficacy and safety of Anluohuaxian in the treatment of patients with severe Coronavirus disease 2019- a multicenter, open label, randomized controlled study: a structured summary of a study protocol for a randomised controlled trialLetter Published on 2020-06-082022-10-29 Journal: Trials [Category] Coronavirus, SARS, [키워드] 6-minute walking distance actual Alpha analyst Anluohuaxian antiviral drugs brand bronchial asthma Care change changes Chinese Chinese herbal medicines chronic obstructive Colchicine Combined completion Compliance composed computer tomography Confirmed connective tissue control group Coronavirus disease 2019 COVID-19 criteria Cyclophosphamide cytokine diagnosed dissemination distribution drug Efficacy and safety element Endocrine enrolled Estimated evaluate expected experimental group explained facilitate fibrosis glucocorticoid groups hepatic fibrosis High-resolution history Hormones HRCT Huoshenshan Hospital Imatinib include indicate interferon-γ interstitial Interstitial lung disease investigators involved IWRS Kidney disease lactating liver lobular lung maximum Mental Disorders minimum multicenter Nasopharyngeal swab Necrosis negative neurologic Nintedanib nodule not blinded nucleic acid test number objective open label outcome outcome assessors participant Participants Pathogenesis pathway Patient pharmaceutical pill professional proportion protocol provided pulmonary pulmonary disease pulmonary fibrosis random randomised randomised controlled trial randomization randomization system Randomized Randomized controlled trial randomly divided RCT recruitment Research research drug respiratory specimen Sample size Science second selected severe COVID-19 sputum statistical status Study protocol subject technology therapeutic drug Tongji Hospital treated Treatment treatment group Trial Union Hospital university variety website West Wuhan Year [DOI] 10.1186/s13063-020-04399-8 PMC 바로가기 [Article Type] Letter
Interstitial Lung Disease and Psoriasis in a Child With Aicardi-Goutières Syndromearticle Published on 2020-05-202024-09-02 Journal: Frontiers in immunology [Category] 대상포진, [키워드] Aicardi-Goutières syndrome IFIH1/MDA5 Interstitial lung disease psoriasis pulmonary hypertension [DOI] 10.3389/fimmu.2020.00985 PMC 바로가기 [Article Type] article
Results of Multilevel Containment Measures to Better Protect Lung Cancer Patients From COVID-19: The IEO ModelOncology Published on 2020-04-222022-10-31 Journal: Frontiers in Oncology [Category] COVID-19, [키워드] acute respiratory syndrome administration Admission anticancer applied benefit Better Cancer Care China clinical conditions Comorbidities concerning Containment containment measures Contamination coronavirus coronavirus disease country Course COVID-19 COVID-19 outbreak COVID-19 pandemic COVID-19 severity disease Elderly patient European expected Follow-up visit high risk histology hospital hospitals Infection International Interstitial lung disease Italy lung cancer lung cancer patient management measure media Model Mortality myelosuppression National Novel coronavirus oncologist oncology organization pandemic Patient Potential PROTECT pulmonary complication receiving recommendation reported required Result risk SARS-CoV-2 SARS-CoV2 infection significantly Spread suspected patient Symptom the disease Toxicity Treatment WHO with COVID-19 World Health Organization [DOI] 10.3389/fonc.2020.00665 PMC 바로가기 [Article Type] Oncology
Practical Considerations for the Diagnosis and Treatment of Fibrotic Interstitial Lung Disease During the Coronavirus Disease 2019 PandemicArticle Published on 2020-04-222023-07-01 Journal: Chest [Category] SARS, [키워드] ACE-2, Angiotensin-converting enzyme 2 coronavirus disease COVID-19, Coronavirus disease 2019 Diagnosis ILD, interstitial lung disease Interstitial lung disease IPF, Idiopathic pulmonary fibrosis MDD, multidisciplinary discussion PFT, pulmonary function test PPE, Personal protective equipment RT-PCR, Reverse Transcription-Polymerase Chain Reaction SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2 SLB, surgical lung biopsy Treatment [DOI] 10.1016/j.chest.2020.04.019 PMC 바로가기
Rituximab in systemic sclerosis A protocol for systematic reviewarticle Published on 2019-09-202024-09-02 Journal: Molecular biology of the cell [Category] 대상포진, [키워드] cutaneous fibrosis Interstitial lung disease rituximab systematic review Systemic sclerosis [DOI] 10.1097/MD.0000000000017110 PMC 바로가기 [Article Type] article
The 23-valent pneumococcal polysaccharide vaccine in patients with rheumatoid arthritis: a double-blinded, randomized, placebo-controlled trial류마티스 관절염 환자에서의 23가 폐렴구균 다당류 백신: 이중 맹검, 무작위, 위약 대조 시험Research Article Published on 2017-01-252024-08-01 Journal: Arthritis Research & Therapy [Category] 폐렴구균 감염증, [키워드] Interstitial lung disease Pneumococcal polysaccharide vaccine Pneumonia rheumatoid arthritis [DOI] 10.1186/s13075-016-1207-7 PMC 바로가기 [Article Type] Research Article