Arthritis Research & Therapy – Communicable Diseases Research

A Phase 1, randomized, double-blind, placebo-controlled, single- and multiple-dose escalation study to evaluate the safety and pharmacokinetics/pharmacodynamics of PF-06835375, a C-X-C chemokine receptor type 5 directed antibody, in patients with systemic lupus erythematosus or rheumatoid arthritis

Research

Published on 2024-06-062024-09-05
Journal: Arthritis Research & Therapy [Category] update2024,

[키워드] B-cell depletion CXCR5 Efficacy Follicular helper T cells depletion PF-06835375 Pharmacodynamics pharmacokinetics rheumatoid arthritis Safety systemic lupus erythematosus
[DOI] 10.1186/s13075-024-03337-2 PMC 바로가기 [Article Type] Research

Anxiety and depression symptoms in adolescents and young adults with juvenile idiopathic arthritis: results of an outpatient screening

Research

Published on 2024-04-102024-09-05
Journal: Arthritis Research & Therapy [Category] update2024,

[키워드] adolescents Anxiety Depression Internalizing symptoms juvenile idiopathic arthritis mental health Screening
[DOI] 10.1186/s13075-024-03312-x PMC 바로가기 [Article Type] Research

Clinical phenotypes and prognoses of microscopic polyangiitis based on kidney biopsies

article

Published on 2023-12-072024-09-02
Journal: Arthritis Research & Therapy [Category] 대상포진,

[키워드] clinical phenotypes Kidney biopsy Microscopic Polyangiitis Prognosis
[DOI] 10.1186/s13075-023-03218-0 PMC 바로가기 [Article Type] article

Efficacy and safety of tofacitinib in patients with rheumatoid arthritis by previous treatment: post hoc analysis of phase II/III trials

article

Published on 2023-11-022024-09-02
Journal: Arthritis Research & Therapy [Category] 대상포진,

[키워드] antirheumatic agents Arthritis methotrexate
[DOI] 10.1186/s13075-023-03154-z PMC 바로가기 [Article Type] article

Janus kinase inhibitor, tofacitinib, in refractory juvenile dermatomyositis: a retrospective multi-central study in China

article

Published on 2023-10-182024-09-02
Journal: Arthritis Research & Therapy [Category] 대상포진,

[키워드] Biologic therapy Janus kinase inhibitor juvenile dermatomyositis refractory Tofacitinib
[DOI] 10.1186/s13075-023-03170-z PMC 바로가기 [Article Type] article

Upadacitinib effectiveness and factors associated with minimal disease activity achievement in patients with psoriatic arthritis: preliminary data of a real-life multicenter study

article

Published on 2023-10-112024-09-02
Journal: Arthritis Research & Therapy [Category] 대상포진,

[키워드] Axial inflammation Bio-refractory Clinical efficacy Minimal disease activity Peripheral arthritis psoriasis psoriatic arthritis real life Safety Upadacitinib
[DOI] 10.1186/s13075-023-03182-9 PMC 바로가기 [Article Type] article

Efficacy and safety of upadacitinib in patients with ankylosing spondylitis refractory to biologic therapy: 1-year results from the open-label extension of a phase III study

article

Published on 2023-09-182024-09-02
Journal: Arthritis Research & Therapy [Category] 대상포진,

[키워드] ankylosing spondylitis biologic Inadequate response Janus kinase inhibitor Open-label extension refractory tumor necrosis factor Upadacitinib
[DOI] 10.1186/s13075-023-03128-1 PMC 바로가기 [Article Type] article

Comparative risk of infections between JAK inhibitors versus TNF inhibitors among patients with rheumatoid arthritis: a cohort study

article

Published on 2023-07-262024-09-02
Journal: Arthritis Research & Therapy [Category] 대상포진,

[키워드] Asian infections Janus kinase inhibitors rheumatoid arthritis tumor necrosis factor inhibitors
[DOI] 10.1186/s13075-023-03111-w PMC 바로가기 [Article Type] article

Efficacy and safety of upadacitinib in patients with active psoriatic arthritis and axial involvement: results from two phase 3 studies

article

Published on 2023-04-102024-09-02
Journal: Arthritis Research & Therapy [Category] 대상포진,

[키워드] adalimumab Ankylosing Spondylitis Disease Activity Score (ASDAS) Axial involvement Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) Janus kinase (JAK) inhibitor Psoriatic arthritis (PsA) Safety Upadacitinib
[DOI] 10.1186/s13075-023-03027-5 PMC 바로가기 [Article Type] article

Clinical and serological association of plasma 25-hydroxyvitamin D (25(OH)D) levels in lupus and the short-term effects of oral vitamin D supplementation

article

Published on 2023-01-032024-09-05
Journal: Arthritis Research & Therapy [Category] update2024,

[키워드] Autoimmunity cholecalciferol interferon SLE SLEDAI-2KG
[DOI] 10.1186/s13075-022-02976-7 PMC 바로가기 [Article Type] article