Respiratory distress syndrome – Page 13 – Communicable Diseases Research

7-Ketocholesterol: Effects on viral infections and hypothetical contribution in COVID-19

7-케토콜레스테롤: 바이러스 감염에 미치는 영향 및 COVID-19에 대한 가설적 기여

Review

Published on 2021-09-012022-09-11
Journal: The Journal of steroid biochemistry and molecular [Category] MERS, 바이오마커, 치료제,

Pneumocytes are distinguished by highly elevated expression of the ER stress biomarker GRP78, a co-receptor for SARS-CoV-2, in COVID-19 autopsies

폐렴 세포는 COVID-19 부검에서 SARS-CoV-2의 공동 수용체인 ER 스트레스 바이오마커 GRP78의 고도로 상승된 발현으로 구별됩니다

Article

Published on 2021-09-012022-09-11
Journal: Cell stress & chaperones [Category] SARS, 치료기술, 치료법, 치료제,

[키워드] acute respiratory distress syndrome age alveolar damage ARDS Autopsy Biomarker cellular Co-receptor controls COVID-19 COVID-19 patient death rate death rates Deceased Degradation determined by distress edema elevated ER stress examined exhibited expression feature Gender Glucose GRP78 Host hyaline membrane hyaline membrane formation immune modulation immunohistochemical staining immunostaining implicated independent independent of Inflammation Interaction lung Lung injury Lungs Macrophage macrophages modulate morbidity morbidity and mortality Non-COVID-19 nucleocapsid protein overlap overlapped pathway pneumocyte Pneumocytes Protein Proteostasis receptor reducing Resilience respiratory distress Respiratory distress syndrome robust SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections severe lung injury staining surgical resection syndrome therapeutic strategy tissue repair unfolded protein response UPR Vaccinations was increased
[DOI] 10.1007/s12192-021-01230-4 PMC 바로가기 [Article Type] Article

Serum Krebs von den Lungen-6 levels are associated with mortality and severity in patients with coronavirus disease 2019

혈청 Krebs von den Lungen-6 수준은 2019년 코로나바이러스 질환 환자의 사망률 및 중증도와 관련이 있습니다

Article

Published on 2021-09-012022-09-11
Journal: Respiratory investigation [Category] MERS, SARS, 바이오마커,

[키워드] acute respiratory distress acute respiratory distress syndrome Admission an area analyzed ARDS arterial partial pressure of oxygen cardiovascular center coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 cutoff value determine disease disease severity enrolled fraction Hospitalized Japanese Krebs von den Lungen-6 medical record medical records Mortality negative correlation nonsurvivor nonsurvivors on admission outcome oxygen partial pressure Patient patients with COVID-19 Predictive Prognosis progressed reported respiratory Respiratory Center respiratory distress Respiratory distress syndrome sensitivity serum severe disease severity significantly specificity survivor syndrome the disease U/mL
[DOI] 10.1016/j.resinv.2021.04.002 PMC 바로가기 [Article Type] Article

JAK-inhibitors for coronavirus disease-2019 (COVID-19): a meta-analysis

코로나바이러스 질병-2019(COVID-19)에 대한 JAK 억제제: 메타 분석

Meta-Analysis

Published on 2021-09-012022-09-11
Journal: Leukemia [Category] SARS, 임상, 치료법,

Endothelial Dysfunction, Inflammation, and Oxidative Stress in COVID-19—Mechanisms and Therapeutic Targets

COVID-19의 내피 기능 장애, 염증 및 산화 스트레스 - 메커니즘 및 치료 목표

Review

Published on 2021-08-212022-09-12
Journal: Oxidative Medicine and Cellular Longevity [Category] MERS, SARS, 진단,

[키워드] acute respiratory distress acute respiratory distress syndrome alveolar damage cardiovascular system caused characterized clinical manifestations Coagulopathy COVID-19 COVID-19 pandemic COVID-19 pathogenesis Cytokine storm death disease endothelial Endothelial dysfunction endotheliopathy form healthcare Inflammation investigated lung lung damage mechanism Mild symptom mild symptoms New observation outbreak oxidative stress respiratory distress Respiratory distress syndrome Respiratory failure responsible SARS-CoV-2 SARS-COV-2 infection syndrome target the disease therapeutic target therapeutic targets virus with COVID-19
[DOI] 10.1155/2021/8671713 PMC 바로가기 [Article Type] Review

Salicylanilides Reduce SARS-CoV-2 Replication and Suppress Induction of Inflammatory Cytokines in a Rodent Model

Salicylanilides는 설치류 모델에서 SARS-CoV-2 복제를 감소시키고 염증성 사이토카인의 유도를 억제합니다

Article

Published on 2021-08-132022-09-11
Journal: ACS Infectious Diseases [Category] SARS, 변종,

[키워드] acute respiratory distress acute respiratory distress syndrome Anti-SARS-CoV-2 Activity Antiviral Asymptomatic class Combination Compound contagious COVID-19 COVID-19 infections COVID-19 pandemic cytokine Cytokines Efficacy evaluated induction infected individual infected individuals inhibitory activity involved Ionophore lead mitigate Model modulate pharmacokinetic Prophylactic question reduce respiratory distress Respiratory distress syndrome rodent salicylanilide salicylanilides. SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 virus scourge screened shown syndrome Therapeutics Vaccine variants Vero cells viral loads virus viruses weight loss
[DOI] 10.1021/acsinfecdis.1c00253 PMC 바로가기 [Article Type] Article

Combining IL-6 and SARS-CoV-2 RNAaemia-based risk stratification for fatal outcomes of COVID-19

COVID-19의 치명적인 결과에 대한 IL-6 및 SARS-CoV-2 RNA빈혈 기반 위험 계층화 결합

Research Article

Published on 2021-08-112022-09-12
Journal: PLoS ONE [Category] MERS, SARS, 진단,

[키워드] Accuracy acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Admission clinical collected copy number coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients Deterioration ECMO ELISA kit extracorporeal membrane oxygenation FiO2 fraction high mortality high risk highest hyperinflammation identify IL-6 In-hospital death increase interleukin intubation Laboratory log-rank test mechanical ventilation moderate to severe objective outcome oxygen oxygen saturation pandemic Patient patients died patients with moderate plasma Predictive prognostic biomarker Prognostic biomarkers quantitative PCR required respiratory distress Respiratory distress syndrome Result risk stratification RNA SARS-CoV-2 SARS-CoV-2 RNA severe acute respiratory syndrome Coronavirus severe COVID-19 significantly higher SpO2 SpO2/FiO2 syndrome variables were assessed
[DOI] 10.1371/journal.pone.0256022 PMC 바로가기 [Article Type] Research Article

The lethal internal face of the coronaviruses: Kidney tropism of the SARS, MERS, and COVID19 viruses

코로나바이러스의 치명적인 내부 얼굴: SARS, MERS 및 COVID19 바이러스의 신장 친화성

Review

Published on 2021-08-012022-09-11
Journal: Iubmb Life [Category] SARS, 바이오마커, 유전자 메커니즘,

[키워드] 2019-nCoV ACE2 acute respiratory distress acute respiratory distress syndrome ARDS attacked cause Cell cells characterized Complication coronavirus Coronavirus infection CoV infection COVID19 damages distal DPP4 failure functions heart humans induce infected patients infecting infective kidney kidney tissue knowledge liver mechanism MERS MERS-CoV MERS-CoV infection mortality rate Novel coronavirus organ outbreak pandemic pathology Patient Proteinuria provided receptor renal dysfunction renal failure renal impairment respiratory distress Respiratory distress syndrome SARS SARS-CoV SARS-CoV-2 syndrome target triggered viral infection viral invasion virus
[DOI] 10.1002/iub.2516 PMC 바로가기 [Article Type] Review

Comprehensive investigation of RNA-sequencing dataset reveals the hub genes and molecular mechanisms of coronavirus disease 2019 acute respiratory distress syndrome

RNA 시퀀싱 데이터 세트에 대한 포괄적인 조사는 코로나바이러스 질병 2019 급성 호흡 곤란 증후군의 허브 유전자 및 분자 메커니즘을 보여줍니다

Article

Published on 2021-08-012022-09-11
Journal: IET systems biology [Category] 유전자 메커니즘,

[키워드] acute respiratory distress acute respiratory distress syndrome Analysis approach ARDS ARDS patients CD4 Cell complement Comprehensive comprehensive analysis control group coronavirus disease Coronavirus disease 2019 correlation COVID-19 COVID-19 ARDS patient cytokine dataset DEGs differentially expressed gene Differentially expressed genes drug eosinophil eosinophils follicular Functional enrichment analysis G-protein Glutamate GSE163426 hub genes Immune cell infiltration infiltration involved Macrophage macrophages mechanism molecular mechanism molecular mechanisms network analysis pathway patients potential molecular receptor respiratory distress Respiratory distress syndrome reveal RNA sequencing RNA-sequencing significantly syndrome T cell T cells was obtained
[DOI] 10.1049/syb2.12034 PMC 바로가기 [Article Type] Article

Right Ventricular Strain Is Common in Intubated COVID-19 Patients and Does Not Reflect Severity of Respiratory Illness

우심실 긴장은 삽관된 COVID-19 환자에서 흔하며 호흡기 질환의 중증도를 반영하지 않습니다

Article

Published on 2021-08-012022-09-11
Journal: Journal of Intensive Care Medicine [Category] 임상,

[키워드] acute respiratory distress acute respiratory distress syndrome Affect age airway alveolar Analysis Atelectasis Biomarkers cardiac dysfunction chest imaging common comorbid conditions coronavirus disease Coronavirus disease 2019 correlated correlation COVID-19 COVID-19 patient COVID-19 patients Critically ill critically ill COVID-19 patients demographics determine develop disease severity dysfunction echocardiographic had more hypoxic illness induce Inflammation inflammatory markers investigated Laboratory Lung compliance Lung disease lung mechanics mechanical ventilation mechanically ventilated mechanically ventilated COVID-19 patients medical record medications myocardial damage myocarditis Non-COVID-19 non-COVID-19 acute respiratory distress syndrome outcome Oxygenation pathogenic mechanism pathology Patient Plateau pressure Pulmonary embolism quantified receiving reduced respiratory respiratory distress Respiratory distress syndrome Respiratory failure right right ventricle Right ventricular RV dysfunction secondary to serum troponin severity strain syndrome thrombosis Tidal volume vasoconstriction vasopressor requirements Ventilation ventilatory ventilatory parameters ventricular Volume
[DOI] 10.1177/08850666211006335 PMC 바로가기 [Article Type] Article