Absence of SARS-CoV-2 antibodies in pre-pandemic plasma from children and adults in Vietnam베트남의 어린이와 성인의 전염병 전 혈장에서 SARS-CoV-2 항체의 부재Article Published on 2021-10-012022-09-11 Journal: International Journal of Infectious Diseases [Category] MERS, SARS, 진단, 치료법, [키워드] antibody children COVID-19 cross-reactivity demonstrated Evidence evidence of explain high risk no evidence of nucleocapsid plasma plasma sample plasma samples positive SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 nucleocapsid serological Spike proteins tested zoonosis zoonotic infection zoonotic infections [DOI] 10.1016/j.ijid.2021.07.072 PMC 바로가기 [Article Type] Article
Temporal Associations of the SARS-CoV-2 NP Antigen and Anti-Spike Total Ig Levels with Laboratory Parameters in a Greek Cohort of Hospitalized COVID-19 Patients입원한 COVID-19 환자의 그리스 코호트에서 실험실 매개변수와 SARS-CoV-2 NP 항원 및 항스파이크 총 Ig 수준의 시간적 연관성Research Article Published on 2021-09-202022-09-10 Journal: Canadian Respiratory Journal [Category] MERS, SARS, 치료법, [키워드] anti-S antibody Antigen ARDS Assessing association biochemical parameter Biochemical parameters correlation COVID-19 COVID-19 patient COVID-19 severity develop enrolled evaluated females group Hospitalization hospitalized patient hospitalized patients Immunoglobulin investigated Laboratory laboratory parameter lateral flow Level lung Lungs males marker median age median time nucleocapsid protein Patient patients with pneumonia Pneumonia poor prognosis profile Protein repeated Result risk factor SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 nucleocapsid severe COVID-19 severe COVID-19 patients significant negative correlation specific antibodies spike symptom onset Temporal the SARS-CoV-2 therapeutic interventions Total total Ig [DOI] 10.1155/2021/6590528 PMC 바로가기 [Article Type] Research Article
Analysing the impact of the two most common SARS-CoV-2 nucleocapsid protein variants on interactions with membrane protein in silicoShort Communications Published on 2021-09-202022-10-30 Journal: Journal of Genetic Engineering & Biotechnology [Category] COVID-19, [키워드] acute respiratory syndrome analysed Analysing coronavirus function globe in silico Interaction less M protein membrane protein mutant Mutation N protein N-M protein interactions nucleocapsid protein predicted Protein proteomics reported Research Salt Bridge SARS-CoV-2 SARS-CoV-2 nucleocapsid sensitivity significant difference supplementary material temperature the SARS-CoV-2 variant virion wild type [DOI] 10.1186/s43141-021-00233-z PMC 바로가기 [Article Type] Short Communications
Early Laboratory Diagnosis of COVID-19 by Antigen Detection in Blood Samples of the SARS-CoV-2 Nucleocapsid ProteinSARS-CoV-2 뉴클레오캡시드 단백질의 혈액 샘플에서 항원 검출을 통한 COVID-19의 조기 실험실 진단Article Published on 2021-09-202022-09-11 Journal: Journal of Clinical Microbiology [Category] SARS, 진단, 치료기술, 치료법, [키워드] Blood blood sample Blood samples collected Concentration confirmatory tests COVID-19 Cutoff detection diagnostic diagnostic sensitivity diagnostic specificity diagnostic test diagnostics ELISA enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay facilitate Hospitalization hospitals Infection Inpatient Laboratory Negative PCR Nosocomial infection Nosocomial infections nucleocapsid protein Outpatient outpatients PCR analysis PCR testing PCR-confirmed plasma positive PCR test Protein reduce Sample SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 nucleocapsid sensitivity serum specificity subsequent Swab symptoms of COVID-19 The diagnostic sensitivity the mean the SARS-CoV-2 [DOI] 10.1128/JCM.01001-21 PMC 바로가기 [Article Type] Article
Long-Term Elevated Inflammatory Protein Levels in Asymptomatic SARS-CoV-2 Infected Individuals무증상 SARS-CoV-2 감염자의 장기간 상승된 염증성 단백질 수치Immunology Published on 2021-09-172022-09-11 Journal: Frontiers in Immunology [Category] SARS, 진단, 치료법, [키워드] activated activated macrophages Alpha antibodies antibody Asymptomatic asymptomatic individual Asymptomatic individuals CD137 CD4 CD69 clinical feature Clinical features clinical monitoring complications controls correlated declined domain Evidence First wave IL18 immune response immune responses individual individuals Infection infections Inflammation inflammation markers inflammatory effect Level life-threatening marker Monocytes N protein no decrease OSM persistence positive individuals Post-infection Protein S-RBD S100A12 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 nucleocapsid seronegative Seropositivity Serum level serum levels severe disease spike spike receptor-binding domain Spread Support T cell T cell response T cell responses the antibody understanding upregulation Viral viral infection viral neutralization [DOI] 10.3389/fimmu.2021.709759 PMC 바로가기 [Article Type] Immunology
Production and persistence of specific antibodies in COVID-19 patients with hematologic malignancies: role of rituximab혈액 악성 종양이있는 Covid-19 환자에서 특정 항체의 생산 및 지속성 : 리툭시 맙의 역할Observational Study Published on 2021-09-142022-09-01 Journal: Blood Cancer Journal [Category] SARS, 임상, 진단, 치료기술, 치료법, [키워드] anti-S antibodies B-cell lymphoma CLD Clinical management Control controls COVID-19 COVID-19 patient declining develop diffuse large B-cell lymphoma DLBCL effective follicular Follicular lymphoma Haematological cancer hematologic Hematologic malignancy hematological HM patient HM patients humoral immune response immune response lymphoma lymphoproliferative disorder MONITOR Multiple myeloma nasal swab nasal swabs nine nucleocapsid Patient PCR-negative persistence Production Prospective Study Protein Reinfection rituximab SARS-CoV-2 SARS-CoV-2 nucleocapsid seroconversion rate seroconversion rates Seropositivity specific antibody syndrome the SARS-CoV-2 Treatment vaccination was performed were measured within 6 months [DOI] 10.1038/s41408-021-00546-9 PMC 바로가기 [Article Type] Observational Study
Just Seeing Is Not Enough for Believing: Immunolabelling as Indisputable Proof of SARS-CoV-2 Virions in Infected Tissue단지 보는 것만으로는 충분하지 않습니다.Article Published on 2021-09-132022-09-10 Journal: Viruses [Category] SARS, 변종, 치료법, [키워드] analysed approach Cell cells correlative microscopy electron microscopy Enough Evidence followed by IHC Immunoelectron microscopy immunohistochemistry immunolabelling light microscopy methodological Microscopy morphology nasopharyngeal Nucleocapsid proteins paraffin-embedded pathologist Pathologists performed proof Protein SARS-CoV-2 SARS-CoV-2 nucleocapsid SARS-CoV-2 protein SARS-CoV-2 proteins SARS-CoV-2 virion SARS-CoV-2 virions Structure structures subsequent tissue transmission electron microscopy Ultrathin sections variant Viral viral particle virion virions [DOI] 10.3390/v13091816 PMC 바로가기 [Article Type] Article
Rapid inactivation of SARS-CoV-2 by titanium dioxide surface coatingResearch Article Published on 2021-09-092022-10-28 Journal: Wellcome Open Research [Category] COVID-19, [키워드] acute respiratory syndrome ambient atomic Care coated with coating Complete Contamination coronavirus detectable droplet evaluated flow cytometry had no Health HIV-1 inactivated inactivation infected cell Infection infection control inoculated interval lentiviral system LIGHT live SARS-CoV-2 Live virus magnitude no significant difference Nosocomial infection occur Post-infection Protein pseudotyped pseudotyped virion Rapid reduction in remained SARS-CoV-2 SARS-CoV-2 nucleocapsid SARS-CoV-2 spike SARS-CoV-2 virus significant effect significantly spike spray stability surface target cell tested TiO2 titanium dioxide titre Transmissibility Transmission VERO E6 cells viability viral variant virus was determined [DOI] 10.12688/wellcomeopenres.16577.2 PMC 바로가기 [Article Type] Research Article
Targeted wastewater surveillance of SARS-CoV-2 on a university campus for COVID-19 outbreak detection and mitigationCOVID-19 발생 감지 및 완화를 위해 대학 캠퍼스에서 SARS-CoV-2의 표적 폐수 감시Article Published on 2021-09-012022-09-11 Journal: Environmental research [Category] SARS, 치료기술, 치료법, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 approach Campus center collected complementary Concentration concentrations Contact tracing Control coronavirus coronavirus disease Coronavirus disease 2019 correlated correlation COVID-19 COVID-19 case COVID-19 cases COVID-19 outbreak COVID-19 pandemic detect disease control Efficacy Epidemiology evaluated fecal Health high-density higher education include Isolation Mild N1 and N2 nursing homes outbreak Outbreak mitigation predictor prevention public health Quantitative RT-PCR receive resulting RNA SARS-CoV-2 SARS-CoV-2 N1 SARS-CoV-2 nucleocapsid SARS-CoV-2 RNA seeking severe acute respiratory syndrome Coronavirus significantly Surveillance System Targeted wastewater surveillance the United State United States university University campus virus wastewater Wastewater-based epidemiology were used with COVID-19 [DOI] 10.1016/j.envres.2021.111374 PMC 바로가기 [Article Type] Article
Early antibody response in health-care professionals after two doses of SARS-CoV-2 mRNA vaccine (BNT162b2)SARS-CoV-2 mRNA 백신(BNT162b2) 2회 접종 후 의료 전문가의 조기 항체 반응Multicenter Study Published on 2021-09-012022-09-11 Journal: Clinical microbiology and infection : the official [Category] SARS, 임상, 진단, 치료법, [키워드] 95% CI acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 anti-spike antibodies anti-spike antibody antibody Antibody Response Antibody titre antibody titres baseline Belgium blood sample Blood samples BNT162b2 BNT162b2 mRNA BNT162b2 mRNA COVID-19 vaccine clinical trial collected conducted coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 vaccine disease dose dose regimen hcp health-care Humoral response immune response individual individuals infected individual infected individuals lead mRNA vaccine multicentre nucleocapsid of BNT162b2 optimum dose professional reached Receptor binding domain respiratory S1 subunit SARS-CoV-2 SARS-CoV-2 nucleocapsid second dose seronegative severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 significantly higher single dose Spike protein Support the S1 subunit the SARS-CoV-2 the spike protein titre two-dose regimen uninfected Vaccine Volunteer were excluded were measured [DOI] 10.1016/j.cmi.2021.05.004 PMC 바로가기 [Article Type] Multicenter Study