SARS-CoV-2 strain – Page 13 – Communicable Diseases Research

A Comprehensive Overview on COVID-19: Future Perspectives

Cellular and Infection Microbiology

Published on 2021-09-142022-10-31
Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID-19, MERS, SARS,

Emergence and expansion of highly infectious spike protein D614G mutant SARS-CoV-2 in central India

중부 인도에서 고발성 스파이크 단백질 D614G 돌연변이 체 SARS-COV-2의 출현 및 확장

Article

Published on 2021-09-132022-09-10
Journal: Scientific Reports [Category] SARS, 변종, 치료기술,

[키워드] A2a Analysis analyzed circulating clade COVID-19 development Economy emergence event Evolution Evolution of SARS-CoV-2 expansion followed by Genome genome sequence Genome sequence data global pandemic globe Health Increased index case index cases India information lockdown molecular evolution Mutant SARS-CoV-2 nanopore technology Oxford pandemic Phylogenetic analysis positive public health referred to research and development responsible SARS-CoV-2 SARS-CoV-2 strain Scientific community span spike protein D614G Spread subsequent Substitution Travel variant Viral protein Viral proteins virus whole genome sequence
[DOI] 10.1038/s41598-021-95822-w PMC 바로가기 [Article Type] Article

Teriflunomide: A possible effective drug for the comprehensive treatment of COVID-19

Research article

Published on 2021-09-112022-10-05
Journal: Current Research in Pharmacology and Drug Discovery [Category] 신약개발, 치료법, 치료제,

[키워드] activity acute respiratory syndrome Analysis Anti-COVID-19/Anti-SARS-CoV-2 drug anti-SARS-CoV-2 antiviral action binding binding affinity binding interaction binding pocket carried caused Computational molecular docking Coronaviral-2 RNA-dependent RNA polymerase (RdRp) coronavirus coronavirus disease COVID-19 COVID-19 cytokine storm docking drug candidate Drug discovery effective evaluate GS-441524 Health hypothetical inhibit inhibitory inhibitory activity leflunomide Ligand lower binding energy mechanism metabolite molecular docking pandemic Particle pharmacological problem Protein RdRP Remdesivir/GS-441524 Replication reported Research RNA RNA-dependent RNA polymerase SARS-CoV-2 SARS-CoV-2 strain server significantly Support Teriflunomide the SARS-CoV-2 therapy Treatment Trial undergo viral replication were used
[DOI] 10.1016/j.crphar.2021.100055 [Article Type] Research article

Outbreaks of SARS-CoV-2 in naturally infected mink farms: Impact, transmission dynamics, genetic patterns, and environmental contamination

자연적으로 감염된 밍크 농장에서 SARS-CoV-2의 발생: 영향, 전염 역학, 유전 패턴 및 환경 오염

Research Article

Published on 2021-09-072022-09-12
Journal: PLoS Pathogens [Category] Fulltext, 조류인플루엔자, 진단,

[키워드] adopted Aerosols amino-acid animals anorexia Awareness Blood calculated characterized classical Clinical signs collected conjunction connective tissue Contamination dead dispersal element epidemiological data event female followed by Generation time Genetic Greece growth growth rate handling Health high mortality histopathological findings Histopathology humans immune Immunity immunized Impact imperative implication indicated Infection initial intensity interstitial pneumonia investigated involved lesions Lineage lineages log lung Lung histopathology male mild depression mink Mortality natural infection Necrosis NGS occurred Occurrence organ organs outbreak Outbreaks parameter pathology Pneumonia proportion public health raised ranged reported respiratory signs responsible RNA RNA copies SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA SARS-CoV-2 strain smooth muscle Spread stages subsequent infections Surveillance Symptom Transmission Transmission dynamics vaccination Vascular Vasculitis vessel Viral load Viral RNA viral strain viral strains virus transmission Welfare wide range of symptoms
[DOI] 10.1371/journal.ppat.1009883 PMC 바로가기 [Article Type] Research Article

Molecular surveillance of the on-going SARS-COV-2 epidemic in Ribeirao Preto City, Brazil

브라질 Ribeirao Preto City에서 진행 중인 SARS-COV-2 전염병의 분자 감시

Article

Published on 2021-09-012022-09-11
Journal: Infection, genetics and evolution : journal of mol [Category] SARS, 변종,

[키워드] accelerated acute respiratory syndrome coronavirus Analysis analyzed B.1.1 B.1.1.28 Brazil causative agent circulating circulation city composed contribute coronavirus country COVID-19 demonstrated epicenter Epidemic Genome genomic Genotype highest initial Lineage lineages majority nanopore technology nasopharyngeal P.1 P.2 pandemic Pandemics performed Phylogenetic phylogenetically Phylogeny positive sample predict respiratory SARS-CoV-2 SARS-CoV-2 lineage SARS-CoV-2 RNA SARS-CoV-2 strain SARS-CoV-2 vaccination second wave sequenced severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 state strain Strains Surveillance surveillance data the SARS-CoV-2 variant variants of concern VoC whole genome worldwide pandemic
[DOI] 10.1016/j.meegid.2021.104976 PMC 바로가기 [Article Type] Article

Doxycycline Inhibition of a Pseudotyped Virus Transduction Does Not Translate to Inhibition of SARS-CoV-2 Infectivity

의사 타입 바이러스 형질 도입의 독시사이클린 억제는 SARS-COV-2 감염성의 억제로 해석되지 않는다.

Article

Published on 2021-09-012022-09-10
Journal: Viruses [Category] SARS, 유전자 메커니즘,

[키워드] angiotensin angiotensin-converting enzyme 2 anti-viral activity approach binding biological processe biological processes caused Clinical data clinical trial clinical trials clinically Compound compounds COVID-19 criteria doxycycline expressing HEK-293 in vitro Infection Infectivity information inhibited inhibition interfere mechanism not affect pandemic platform Pleiotropic effects Pseudotyped virus receptor Replication replication of SARS-CoV-2 resources SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 strain SARS-CoV-2 virus Spike protein Spread surface plasmon resonance T cell T cells tetracyclines the SARS-CoV-2 virus the spike protein therapeutic transduction Vero E6 virus
[DOI] 10.3390/v13091745 PMC 바로가기 [Article Type] Article

Genome-wide analysis of SARS-CoV-2 strains circulating in Vietnam: Understanding the nature of the epidemic and role of the D614G mutation

베트남에서 유행하는 SARS-CoV-2 균주의 게놈 전체 분석: 전염병의 성격과 D614G 돌연변이의 역할 이해

Article

Published on 2021-09-012022-09-11
Journal: Journal of medical virology [Category] SARS, 변종, 치료기술,

[키워드] 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis Chain Reaction circulating Community Contact tracing coronavirus coronavirus disease Coronavirus disease 2019 country COVID-19 cycle threshold D614G D614G mutation diagnostic test diagnostic tests epidemiological data genome-wide analysis genomic region integration Mutation Next-generation sequencing occur Outbreaks performed polymerase chain polymerase chain reaction Prevalence Prevention and control quarantine SARS-CoV-2 SARS-CoV-2 strain SARS-CoV-2 transmission Sequencing severe acute respiratory syndrome Coronavirus strain Strains the epidemic understanding Vietnam virulence whole-genome sequencing
[DOI] 10.1002/jmv.27103 PMC 바로가기 [Article Type] Article

Profile of humoral and cellular immune responses to single doses of BNT162b2 or ChAdOx1 nCoV-19 vaccines in residents and staff within residential care homes (VIVALDI): an observational study

Observational Study

Published on 2021-09-012022-10-05
Journal: The Lancet. Healthy longevity [Category] SARS, 임상,

[키워드] ACE2 binding Adaptive immune response age All participant antibody Antibody Response Antibody titre antibody titres B.1.1.7 B.1.351 B.1.351 variant blood sample BNT162b2 Care Cellular immune response cellular response ChAdOx1 nCoV-19 ChAdOx1 nCoV-19 vaccine Cohort collected correlated correlation country Coverage COVID-19 COVID-19 mortality COVID-19 vaccination COVID-19 vaccine defined Department Evidence extended interval first dose history humoral IgG antibody immune responses immunoassay Impact independent Infection infection with SARS-CoV-2 Interaction IQR kinetic magnitude median median age of BNT162b2 Older P.1 variant P.1 variants participant Participants peptide positive pre-vaccination profile resident response SARS-COV-2 infection SARS-CoV-2 strain second dose serological evidence significantly lower single dose Spike protein spike-specific IgG T-cell Response tested titre vaccination Vaccine vaccine dose variant variants of SARS-CoV-2 were assessed were excluded
[DOI] 10.1016/S2666-7568(21)00168-9 PMC 바로가기 [Article Type] Observational Study

Higher entropy observed in SARS-CoV-2 genomes from the first COVID-19 wave in Pakistan

파키스탄의 첫 번째 코비드 -19 파에서 SARS-COV-2 게놈에서 관찰 된 더 높은 엔트로피

Research Article

Published on 2021-08-312022-09-10
Journal: PLoS ONE [Category] MERS, SARS, 변종,

[키워드] (RdRp 5’ UTR Analysis B.1 B.6 Capital change clade clades COVID-19 D614G Diversity Evolution except for exhibited Genetic Genome genome sequence genomes glycoprotein highest investigated isolates Laboratory lead material Mutation mutation rate Mutation rates not significant pandemic Phylogeny Q57H RdRP relative Result RNA RNA dependent RNA polymerase RNA polymerase SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes SARS-CoV-2 strain SARS-CoV-2 strains selection pressure sequence sequences Site spike spike glycoprotein stability strain Strains subsequent territory transmitted virus were used
[DOI] 10.1371/journal.pone.0256451 PMC 바로가기 [Article Type] Research Article

Origin of imported SARS-CoV-2 strains in The Gambia identified from whole genome sequences

전체 게놈 서열에서 확인 된 감비아에서 수입 된 SARS-COV-2 균주의 기원

Research Article

Published on 2021-08-312022-09-10
Journal: PLoS ONE [Category] MERS, SARS, 치료기술,

[키워드] addition Analysis approach Asian baseline baseline data Contact contribute COVID-19 determine Economy European genomic genomic data global pandemic Health care Health care system health care systems index case index cases Infection information Local origin Phylogenetic analysis populations positive SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 disease SARS-CoV-2 strain SARS-CoV-2 virus sequenced Sequencing shown source of infection strain sub-Saharan Africa subsequent the SARS-CoV-2 virus Transmission Travel WGS while whole genome whole genome sequence Whole genome sequencing Wuhan Wuhan, China
[DOI] 10.1371/journal.pone.0241942 PMC 바로가기 [Article Type] Research Article