Significance of peripheral blood indexes in differential diagnoses of SARS-CoV-2 and New Bunia virusSARS-COV-2 및 New Bunia 바이러스의 감별 진단에서 말초 혈액 지수의 중요성Article Published on 2021-07-082022-08-31 Journal: Scientific Reports [Category] SARS, 바이오마커, [키워드] 2019-nCoV absolute lymphocyte Biomarkers Blood C-reactive protein C-reactive protein (CRP CD4 characteristic clinical Clinical data collected control group COVID-19 COVID-19 patient CRP Cytokines diagnostic value differential diagnose differential diagnosis Fever greater groups healthy control hospitalized patients IL-6 infections Infectious diseases initial initial stage Laboratory lymphocyte New Outcomes research parameters Patient PCT Peripheral blood procalcitonin receiver receiver operating characteristic Respiratory tract diseases Retrospective analysis ROC ROC Curve ROC curves SARS-CoV-2 Significance significantly syndrome T lymphocyte thrombocytopenia TNF-α virus virus infection was performed WBC [DOI] 10.1038/s41598-021-93519-8 PMC 바로가기 [Article Type] Article
A macrophage attack culminating in microthromboses characterizes COVID 19 pneumonia미세혈전증에서 정점을 이루는 대식세포 공격은 COVID 19 폐렴을 특징짓습니다Original Article Published on 2021-07-072022-09-10 Journal: Immunity, Inflammation and Disease [Category] SARS, 치료기술, [키워드] acute phase alveolar cells Bacterial bacterial pneumonia Blood level blood levels blood tissues bloodstream Brain caused characteristic circulation clotting Coagulation complexes COVID COVID 19 COVID‐19 COVID‐19 patient disorders Disseminated intravascular coagulation Effect elevated Evidence evidence of explain ferritin ferritin level FIBRIN fibrin clot fibrinogen FIVE Frequency human animals ICU immune immune activation immune response infections infiltrating infiltration Innate immunity input intravascular coagulation kidney Liver transplantation lung infiltrates Lungs Macrophage Macrophage infiltration macrophages monomer neutrophilic organ oropharynx pandemic panoply Patient patients phagocytic Pneumonia Protein Proteins prothrombotic referred to reflect respiratory respiratory virus Result SARS‐CoV‐2 tandem thought thrombocytopenia THROMBOPLASTIN tissue Tissue Factor vasculature Viral Viral pneumonia viral retroviral virus Whole blood [DOI] 10.1002/iid3.482 PMC 바로가기 [Article Type] Original Article
Mechanisms of Immunothrombosis in Vaccine-Induced Thrombotic Thrombocytopenia (VITT) Compared to Natural SARS-CoV-2 Infection천연 SARS-CoV-2 감염과 비교한 백신 유도 혈전성 혈소판 감소증(VITT)의 면역혈전증 기전Review Published on 2021-07-012022-09-12 Journal: Journal of autoimmunity [Category] SARS, 진단, [키워드] Activation Adenovirus anti-SARS-CoV-2 autoantibody autoantigen Autoimmune Autoimmunity Bacterial bacterial cell buffer cavernous sinus cellular ChAdOx1 coagulation cascade complexes contribute COVID-19 COVID-19 pneumonia related thrombosis DNA DNA molecules EDTA event extracellular DNA Factors heparin Heparin induced thrombocytopenia (HIT) DNA-PF4 interactions. VITT model immune tolerance Immunity immunothrombosis independent initiate innate immune Innate immunity Interaction interactions interferon response intestinal intestine intramuscular Local mechanism molecular natural nuclear PF4 platelet activation Pneumonia Protein Proteins SARS-CoV-2 SARS-COV-2 infection shown SLE stimulate susceptible individual thrombocytopenia thrombosis thrombotic TLR Tolerance vaccination Vaccine Vaccine induced thrombotic thrombocytopenia (VITT). venous Viral RNA viral spike protein [DOI] 10.1016/j.jaut.2021.102662 PMC 바로가기 [Article Type] Review
Outcomes and management of immune thrombocytopenia secondary to COVID-19: Cleveland clinic experience코로나19에 따른 면역성 혈소판감소증의 결과와 관리: 클리블랜드 클리닉 경험Article Published on 2021-07-012022-09-11 Journal: Transfusion [Category] SARS, 바이오마커, 진단, [키워드] acquired disease age autoantibodies autoantibody bleeding Blood Blood Transfusion causes characterized Cleveland Clinical characteristics Complete coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 diagnosis COVID-19 patients diagnosed effective Eltrombopag glucocorticoid Glucocorticoids GRADE grade 3 Health Organization hypoxic respiratory failure immune Immune thrombocytopenia Immunoglobulin Intravenous immunoglobulin IVIG male management mechanical ventilation median age median time MOST occurred Patient patients Platelets required Respiratory failure response to treatment safety profile secondary to severity Severity Score Standard standard treatment survived Symptom the median thrombocytopenia Treatment was used WHO World Health Organization [DOI] 10.1111/trf.16368 PMC 바로가기 [Article Type] Article
An observational study to identify the prevalence of thrombocytopenia and anti-PF4/polyanion antibodies in Norwegian health care workers after COVID-19 vaccinationCOVID-19 백신 접종 후 노르웨이 의료 종사자의 혈소판 감소증 및 항-PF4/다음이온 항체의 유병률을 확인하기 위한 관찰 연구Observational Study Published on 2021-07-012022-09-11 Journal: Journal of thrombosis and haemostasis : JTH [Category] SARS, 임상, 치료기술, [키워드] activating adverse effects Adverse reactions antibody Antibody testing AstraZeneca AZD1222 clinical trials Cohort Combination COVID-19 COVID-19 vaccination COVID-19 vaccine COVID-19 vaccines COVID-19 vaccines/adverse effects drug related side effects and adverse reactions Effect European country European Medicines Agency first dose Health care Health care worker hospital identify immune Immunity immunoassay individual introduced knowledge majority Norway optical optical density Perceived risk Platelet platelet factor 4 presenting Prevalence recruited referred to Registered reported SARS-CoV-2 screened side Side effect study participant Study participants subject the vaccine thrombocytopenia thrombosis thrombotic Thrombotic thrombocytopenia vaccination Vaccine [DOI] 10.1111/jth.15352 PMC 바로가기 [Article Type] Observational Study
Anti-PF4 antibody negative cerebral venous sinus thrombosis without thrombocytopenia following immunization with COVID-19 vaccine in an elderly non-comorbid Indian male, managed with conventional heparin-warfarin based anticoagulation기존의 헤파린-와파린 기반 항응고제로 관리되는 노인 비동환 인도 남성에서 COVID-19 백신 접종 후 혈소판 감소증이 없는 항-PF4 항체 음성 대뇌 정맥동 혈전증Case Reports Published on 2021-07-012022-09-12 Journal: Diabetes & metabolic syndrome [Category] MERS, SARS, 진단, [키워드] Abstract antibody anticoagulation ChAdOx1 ChAdOx1 nCOV-19 (Oxford-AstraZeneca)/COVISHIELD COVID-19/Vaccination CVT immunization male thrombocytopenia thrombosis Vaccine venous VITT with COVID-19 [DOI] 10.1016/j.dsx.2021.06.021 PMC 바로가기 [Article Type] Case Reports
Perspectives on vaccine induced thrombotic thrombocytopenia백신 유발성 혈전성 혈소판 감소증에 대한 전망Review Published on 2021-07-012022-09-12 Journal: Journal of autoimmunity [Category] SARS, 진단, [키워드] Activation adverse effect aggregation approach AstraZeneca AstraZeneca vaccine Atypical autoantibody Autoimmune Autoimmune disease bind Brazil bystander catastrophic ChAdOx1 ChAdOx1 nCoV-19 ChAdOx1 nCoV-19 vaccine classical Compound contribute country COVID-19 disease onset disorder disorders France Germany Health heparin-induced thrombocytopenia HIT homological Hypercoagulation Hyperstimulation Hypothesis immune cells Immune-mediated individual infect Manifestations molecular molecular mimicry occur Oxford participant pathogenic autoantibodies Patient PF4 Platelet Randomized controlled trials receptor Safe SARS-CoV-2 sequence South Africa symptomatic the vaccine thrombocytopenia thrombosis thrombotic triggered vaccination Vaccine venous Viral antigen [DOI] 10.1016/j.jaut.2021.102663 PMC 바로가기 [Article Type] Review
Biomarkers of cytokine storm as red flags for severe and fatal COVID-19 cases: A living systematic review and meta-analysis심각하고 치명적인 코비드 -19 사례에 대한 적기로서의 사이토 카인 폭풍의 바이오 마커 : 살아있는 체계적인 검토 및 메타 분석Meta-Analysis Published on 2021-06-292022-08-13 Journal: PLoS ONE [Category] Biochemistry, MERS, SARS, 바이오마커, [키워드] abstracts Analysis aspartate Aspartate aminotransferase Biomarker Biomarkers C-reactive protein C-Reactive-Protein conducted Confidence intervals Controlled controlled trials COVID-19 creatinine cytokine Cytokine storm Cytokine storm syndrome D-dimer database elevated eligible fatal COVID-19 ferritin Final final analysis for inclusion Grey literature hematology Hyperferritinemia IBECS identify interleukin interleukin-6 Laboratory laboratory biomarker laboratory biomarkers laboratory data laboratory parameter Laboratory parameters Lactate lactate dehydrogenase leucocyte leucocytes leukocytes LILACS Lymphocytes lymphopenia mean difference mean differences meta-analyses Meta-analysis Mild moderate neutrophil Neutrophils Newcastle-Ottawa Scale objective parameters patients Platelets poor prognosis predictor procalcitonin retrieved risk of bia screened selected serum serum interleukin-6 levels severe and fatal COVID-19 cases severe COVID-19 syndrome synonym systematic review systemic inflammation the cytokine storm the MEDLINE the Newcastle-Ottawa Scale thrombocytopenia was performed [DOI] 10.1371/journal.pone.0253894 PMC 바로가기 [Article Type] Meta-Analysis
US Case Reports of Cerebral Venous Sinus Thrombosis With Thrombocytopenia After Ad26.COV2.S Vaccination, March 2 to April 21, 20212021년 3월 2일부터 4월 21일까지 Ad26.COV2.S 백신 접종 후 혈소판 감소증을 동반한 대뇌 정맥동 혈전증에 대한 미국 사례 보고Case Reports Published on 2021-06-222022-09-11 Journal: JAMA [Category] 비임상, [키워드] Ad26 Ad26.COV2.S Ad26.COV2.S vaccine adenoviral vector Adverse age antibody AstraZeneca authorization Autoimmune back pain breath Case series case sery cerebral ChAdOx1 ChAdOx1 nCoV-19 ChAdOx1 nCoV-19 vaccine clinical Clinical course Clinicians Contraceptive use Course COVID-19 vaccine death described Diagnosis discharged home dose ELISA Emergency Emergency use authorization enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay EUA Europe events Follow-up Guidance headache heparin heparin treatment heparin-induced thrombocytopenia Hospitalization Hospitalized Hypothyroidism ICU care initial intensive care intensive care unit Intracerebral hemorrhage Laboratory tests mechanism medical record National non-ICU obesity oral contraceptive outcome Patient positive ranged receipt recipients report reported Reporting resulting risk factor Sinus Sinus thrombosis symptom onset System tested thrombocytopenia thrombosis time Treatment vaccination venous venous sinus white women [DOI] 10.1001/jama.2021.7517 PMC 바로가기 [Article Type] Case Reports
Blood coagulation parameter abnormalities in hospitalized patients with confirmed COVID-19 in Ethiopia에티오피아에서 확인 된 COVID-19를 가진 입원 환자의 혈액 응고 파라미터 이상Observational Study Published on 2021-06-212022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 임상, 치료기술, [키워드] abnormal coagulation abnormality activated partial thromboplastin time aPTT Care Coagulation coagulation parameter Coagulopathy Complication conducted Corona Covid patients COVID-19 COVID-19 patient COVID-19 patients critical COVID-19 patients cross-sectional cross-sectional study defined disease disease severity dominant elevated Germany Hospitalized hospitalized COVID-19 patient hospitalized COVID-19 patients hospitalized patient INR international normalized ratio normalized Older parameter Partial partial thromboplastin time Patient Platelet Platelet count profile Prognostic factor prothrombin Prothrombin time Result statistical analysis statistically significant study participant Study participants subject thrombocytopenia thromboembolic Thromboembolic event Thromboembolic events THROMBOPLASTIN time Treatment Virus Disease Wiesbaden with COVID-19 [DOI] 10.1371/journal.pone.0252939 PMC 바로가기 [Article Type] Observational Study