Cell-free DNA tissues of origin by methylation profiling reveals significant cell, tissue, and organ-specific injury related to COVID-19 severity메틸화 프로파일링에 의한 기원의 무세포 DNA 조직은 COVID-19 중증도와 관련된 중요한 세포, 조직 및 장기 특이적 손상을 나타냅니다Clinical and Translational Article Published on 2021-01-162022-09-14 Journal: Med (New York, N.Y.) [Category] MERS, SARS, 유전자 메커니즘, 진단, [키워드] Abstract advance Affect Award Blood Canada Cell cell-free DNA cfDNA Charle circulating Clinical research Cohort Concentration Context Coronavirus disease 2019 correlated Council COVID-19 COVID-19 patient COVID-19 severity disease Disease progression disease severity DNA DNA profiling Engineering Evidence finding foundation funding healthy controls hospitalized patient hospitalized patients identify independent initiative Injury intubation liquid biopsy liver lung Lungs Medicine Methylation MONITOR NIH organ-specific Patient plasma plasma sample prognostic reveal SARS-CoV-2 Scholar Science severe COVID-19 severe disease significantly increased subject Support supported tissue tissue injury utility viral infection was performed WHO World Health Organization [DOI] 10.1016/j.medj.2021.01.001 PMC 바로가기 [Article Type] Clinical and Translational Article
Domains and Functions of Spike Protein in SARS-Cov-2 in the Context of Vaccine Design백신 설계의 맥락에서 SARS-Cov-2에서 스파이크 단백질의 도메인 및 기능Review Published on 2021-01-142022-09-10 Journal: Viruses [Category] 변종, [키워드] approach BNT162b2 build candidate Cell cell entry cleavage cleaved Context COVID-19 dissect domain ENhance events foundation function human ACE2 receptor human cell hydrophobicity Infection integration interact isoelectric point membrane fusion Moderna mRNA mRNA-1273 vaccine Pfizer Pfizer/BioNTech prefusion produced protein structure Receptor binding S-2P S1 and S2 SARS-2-S SARS-CoV-2 spike Spike protein subsequent subunits the spike protein translated Transmission Vaccine vaccine candidates Vaccine development variety Viral viral entry Viral variants [DOI] 10.3390/v13010109 PMC 바로가기 [Article Type] Review
PTSD in parents of children with severe diseases: a systematic review to face Covid-19 impactReview Published on 2021-01-142022-10-29 Journal: Italian Journal of Pediatrics [Category] Coronavirus, [키워드] Caregivers children Context control group COVID19 database diagnosed Diseases Evidence evidenced Gender illnesses knowledge lack less limit limitation methodology objective outbreak parent parents physical post-traumatic stress symptom PTSD reliability Research researcher Result risk searched Severe diseases systematic review [DOI] 10.1186/s13052-021-00957-1 PMC 바로가기 [Article Type] Review
Washing Hands according to the WHO Guideline since the COVID-19 Outbreak in the Context of Medical Undergraduates at a Tertiary Care Center: A Descriptive Cross-sectional StudyOriginal Article Published on 2020-12-312022-10-30 Journal: JNMA: Journal of the Nepal Medical Association [Category] COVID-19, MERS, SARS, [키워드] COVID-19 prevention hand hygiene age Analysis calculated Care clearance college Committee conducted confidence Context COVID-19 cross-sectional Data collection effective Frequency groups guideline hand hand washing hospital hygiene IMPROVE information interval Lumbini majority medical students notable online questionnaires outbreak participant Point proportion review Spread Teaching Tertiary the WHO Transmission virus was done washing World Health Organization [DOI] 10.31729/jnma.5259 PMC 바로가기 [Article Type] Original Article
Occupational COVID-19 Prevention among Congolese Healthcare Workers: Knowledge, Practices, PPE Compliance, and Safety ImperativesArticle Published on 2020-12-302022-10-29 Journal: Tropical Medicine and Infectious Disease [Category] COVID-19, [키워드] 95%CI adjusted affected age approach assessment category conducted Contact Context COVID-19 COVID-19 epidemic COVID-19 symptoms COVID-19 vaccine cross-sectional Democratic Republic of the Congo disease transmission Government HCW HCWs health care workers health system healthcare worker hospital Infection prevention information knowledge majority Mask media Medical doctor occupational outbreak over pandemic participant Patient care patients Personal protective equipment positive attitude PPE prevention questionnaire receive Safety SARS-CoV-2 WHO’s World Health Organization’ [DOI] 10.3390/tropicalmed6010006 PMC 바로가기 [Article Type] Article
Harnessing Digital Health Technologies During and After the COVID-19 Pandemic: Context MattersViewpoint Published on 2020-12-302022-10-30 Journal: Journal of Medical Internet Research [Category] COVID-19, MERS, SARS, [키워드] Care Characteristics Context coronavirus COVID-19 COVID-19 pandemic Digital Digital health effort Government Health Health care system in-depth analysis introduced Italian lack matter mHealth mobile apps National National Health Service organizational context pandemic professional public health public health system Region responsible technology Telemedicine took place [DOI] 10.2196/21815 PMC 바로가기 [Article Type] Viewpoint
Tele-medicine versus face-to-face consultation in Endocrine Outpatients Clinic during COVID-19 outbreak: a single-center experience during the lockdown periodOriginal Article Published on 2020-12-232022-10-30 Journal: Journal of Endocrinological Investigation [Category] COVID-19, MERS, SARS, [키워드] adopted applied clinic clinical response Context COVID-19 COVID-19 outbreak cross-sectional study disease Efficacy Endocrine Endocrine diseases Endocrine unit Follow-up Health status Hub-spoke organization Italy limit lockdown measure objective offered outcome outcome measure Outpatient Patient patients performed Public recommendation reduced Referral Result setting single-center Telemedicine the patient the WHO viral spread [DOI] 10.1007/s40618-020-01476-2 PMC 바로가기 [Article Type] Original Article
Impact of simulation-based teamwork training on COVID-19 distress in healthcare professionalsObservational Study Published on 2020-12-212022-10-04 Journal: BMC Medical Education [Category] MERS, 임상, [키워드] Anxiety conducted Contact Context control group COVID-19 COVID-19 outbreak COVID-19 pandemic COVID-19 patient COVID19 distress Depression distress effective emotional HADS Health Healthcare professional Healthcare workers wellbeing hospital Impact intervention group Logistic regression Measures Nurse participated Patient Perceived Stress Scale presenting Probability professional Psychological distress receive Result scale Simulation and teamwork Stress Symptom Symptoms with COVID-19 [DOI] 10.1186/s12909-020-02427-4 PMC 바로가기 [Article Type] Observational Study
Health Professionals of Prevention in Italy: The Value of Expertise During COVID-19 PandemicPublic Health Published on 2020-12-212022-10-31 Journal: Frontiers in Public Health [Category] Coronavirus, MERS, SARS, [키워드] activity check Context Course COVID-19 diffusion emergency situation Environment exit Health health care professions hospitals hygiene indication Italian list management National National Health Service New occupational health pandemic prevention principle profession professional protocol provided public health social distancing Surveillance Technician value Workplace [DOI] 10.3389/fpubh.2020.575500 PMC 바로가기 [Article Type] Public Health
Transcriptional Profiling of Immune and Inflammatory Responses in the Context of SARS-CoV-2 Fungal Superinfection in a Human Airway Epithelial ModelArticle Published on 2020-12-112022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] acute respiratory syndrome Analysis Aspergillus characterized chemokines component Context coronavirus coronavirus disease COVID-19 deregulation determine epithelial Evidence form highlight Host transcriptional response Human Human airway epithelium IFN indicate induce Infection Inflammatory responses innate immune invasive invasive aspergillosis management mechanism Model monocyte nasal neutrophil Prevalence Profiling response SARS-CoV-2 superinfection transcriptional transcriptional profiling unique [DOI] 10.3390/microorganisms8121974 PMC 바로가기 [Article Type] Article