In search of preventive strategies: novel high-CBD C annabis sativa extracts modulate ACE2 expression in COVID-19 gateway tissues예방 전략 찾기: 새로운 고 CBD C annabis sativa 추출물은 COVID-19 게이트웨이 조직에서 ACE2 발현을 조절합니다Research Paper Published on 2020-11-302022-08-31 Journal: Aging (Albany NY) [Category] SARS, 치료제, [키워드] ACE2 ACE2 expression ACE2 protein ACE2 receptor acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition airway Alter Analysis angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 Anti-inflammatory anti-inflammatory properties cannabidiol cannabis caused CBD coronavirus COVID-19 COVID-19 pandemic Critical curtail decrease disease disease spread disease susceptibility down-regulate Effect effective expressed gastrointestinal tract Gene Expression Health Canada help host cells human host Inflammation intestinal tissues kidney lung tissue medical cannabis modulate modulation nasal mucosa prevention strategies Protein receptor reduce mortality regulate required Research respiratory Safe SARS-CoV-2 SARS-CoV-2 entry SARS-CoV2 Serine serine protease serine protease TMPRSS2 severe acute respiratory syndrome Coronavirus Spread susceptibility testes therapeutic therapy tissue tissues TMPRSS2 Viral viral entry while working [DOI] 10.18632/aging.202225 PMC 바로가기 [Article Type] Research Paper
Potential implications of SARS-CoV-2 oral infection in the host microbiotaReview Article Published on 2020-11-292022-10-30 Journal: Journal of Oral Microbiology [Category] COVID-19, [키워드] Alter alteration Angiotensin-converting enzyme 2 (ACE2) caused clinical symptom coronavirus disease Course COVID-19 COVID-19 patients Critical Diseases gastrointestinal tract Gut gut microbiota homeostasis Host human host implication Infection Interaction interactions Local lung mechanism microbial community Microbiome microbiota occur oral-gut axis oral-lung axis outbreak pathogenesis of SARS-CoV-2 pathogenic Potential SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome coronavirus 2 virus [DOI] 10.1080/20002297.2020.1853451 PMC 바로가기 [Article Type] Review Article
The Pathophysiology of Gastrointestinal and Hepatic Manifestations of COVID-19Internal Medicine Published on 2020-11-252022-10-31 Journal: Cureus [Category] COVID-19, [키워드] absence ACE2 ACE2 receptor acute respiratory syndrome angiotensin-converting enzyme 2 anorexia Atypical case sery Cathepsins coronavirus Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) COVID-19 demonstrated diarrhea elevated elevated liver enzyme Evidence facilitate Gastrointestinal gastrointestinal and hepatic manefestations Gastrointestinal symptom gastrointestinal tract hepatic hygiene increasingly infect inflammatory markers international public health laboratory abnormality lack literature review liver manifestation Nasopharyngeal swab nasopharynx nausea organ system Pathogenesis Patient polymerase chain protease receptor Respiratory illness respiratory symptoms reverse transcription RT-PCR SARS-CoV-2 sars-cov-2 (severe acute respiratory syndrome coronavirus -2) SARS-CoV-2 infected patient SARS-COV-2 infection Stool Symptoms test negative TMPRSS2 transaminitis transmembrane Transmission viral entry Viral RNA viral shedding while [DOI] 10.7759/cureus.11698 PMC 바로가기 [Article Type] Internal Medicine
COVID-19 and coinfection with Clostridioides ( Clostridium ) difficile in an infant with gastrointestinal manifestationCase Report Published on 2020-11-252022-10-31 Journal: Einstein [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome Admission Clostridioide Clostridioides difficile infection Clostridium Coagulation Coinfecção Coinfection complementary complications coronavirus Coronavirus infections COVID-19 diagnosed diarrhea discharged Evidence exacerbate facilitated Fever gastrointestinal tract Infant Infecções por coronavírus infecção Infection intensive care intravenous Lactente Mild moderate nasopharyngeal Patient pediatric persistence rhinorrhea SARS-CoV-2 Symptom Symptoms the patient transmission of SARS-CoV-2 Trato gastrointestinal vomiting [DOI] 10.31744/einstein_journal/2020RC6048 PMC 바로가기 [Article Type] Case Report
Putative roles of vitamin D in modulating immune response and immunopathology associated with COVID-19Review Published on 2020-11-212022-10-04 Journal: Virus research [Category] SARS, 임상, 조류인플루엔자, [키워드] ACE-2 activate acute respiratory distress syndrome (ARDS) acute respiratory syndrome addition affected anti-inflammatory cytokines antimicrobial peptide bats cardiovascular system cause caused Cell chemokine China co-morbidity Concentration contagious coronavirus Coronavirus-2 COVID-19 COVID-19 case Critical Cytokine storm deficiency Dexamethasone died disrupting ecological ENhance entry of SARS-CoV-2 enzyme epithelial lining evaluate Evidence exaggerated immune response gastrointestinal tract global pandemic host cells Hypovitaminosis D immune evasion immune response immune responses immune system immunopathology incidence incidence of COVID-19 include increase Increased Infection intensive care unit investigated less lung Lungs Macrophage majority membranes MERS modulate modulating multiple mechanism organ pandemic pathogen pathogenesis of SARS-CoV-2 pleiotropic pro-inflammatory cytokine provide Randomized controlled trial receptor reduce reducing renin-angiotensin system replication of SARS-CoV-2 reported respiratory infection risk of COVID-19 SARS-CoV SARS-CoV-2 secretion Spread thought Travel Treatment urgency viral infection virus Vitamin Vitamin D with COVID-19 Wuhan zoonotic disease [DOI] 10.1016/j.virusres.2020.198235 PMC 바로가기 [Article Type] Review
Clinical Features and Pathogenic Mechanisms of Gastrointestinal Injury in COVID-19Review Published on 2020-11-112022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] ACE2 acute respiratory syndrome angiotensin-converting enzyme 2 clinical clinical feature coronavirus coronavirus disease COVID-19 Evidence Gastrointestinal gastrointestinal tract gut microbiota Injury intestine mechanism Occurrence outbreak pathogenic mechanism renin-angiotensin-aldosterone system respiratory tract SARS-CoV-2 Symptom target therapeutic strategy thrombosis TMPRSS2 Tryptophan virus transmission [DOI] 10.3390/jcm9113630 PMC 바로가기 [Article Type] Review
Origin and genomic characteristics of SARS-CoV-2 and its interaction with angiotensin converting enzyme type 2 receptors, focusing on the gastrointestinal tractReview Published on 2020-11-072023-07-01 Journal: World journal of gastroenterology [Category] SARS, [키워드] angiotensin converting enzyme Angiotensin converting enzyme type 2 Angiotensin converting enzyme type 2 receptor COVID-19 gastrointestinal tract renin-angiotensin system SARS-CoV-2 [DOI] 10.3748/wjg.v26.i41.6335 PMC 바로가기 [Article Type] Review
COVID-19 and the gastrointestinal tract: what do we already know?Review Published on 2020-11-052022-10-31 Journal: Einstein [Category] COVID-19, MERS, SARS, [키워드] abdominal pain abstracts affected alteration anorexia article Asymptomatic Betacoronavírus Betacoronavirus Bilirubin caused change Coronavirus infections COVID-19 database death Diagnosis diarrhea disease Doenças gastrointestinais/etiologia dry cough Dyspnea early treatment eliminated Fever Gastrointestinal diseases/etiology Gastrointestinal symptom gastrointestinal symptoms gastrointestinal tract Healthcare professional help Infecções por coronavírus infecção infected individual Infection Laboratory mechanism nausea nausea/vomiting New coronavirus Pandemia pandemic Patient positive Prevalence ranged respiratory tract RNA SARS-CoV-2 searched selected Stool stools Symptoms tested the disease Transmission Trato gastrointestinal typical symptom viral presence Viral RNA vomiting worsening [DOI] 10.31744/einstein_journal/2020RW5909 PMC 바로가기 [Article Type] Review
COVID-19-associated gastrointestinal and liver injury: clinical features and potential mechanismsReview Article Published on 2020-11-022022-10-29 Journal: Signal Transduction and Targeted Therapy [Category] COVID-19, [키워드] abnormality ACE2 acute respiratory syndrome addition angiotensin-converting enzyme 2 caused clinical feature coronavirus COVID-19 diarrhea digestive system Drug-induced liver injury Evidence Fecal–oral transmission Gastrointestinal diseases gastrointestinal symptoms gastrointestinal tract Health hepatic injury highlight infect Infection Infectious diseases Injury liver liver enzymes Liver injury loss of appetite manifestation nausea patients with COVID-19 potential mechanism raise receptor reperfusion injury respiratory symptoms SARS-CoV-2 systemic inflammatory vomiting [DOI] 10.1038/s41392-020-00373-7 PMC 바로가기 [Article Type] Review Article
COVID-19 and Digestive System in Children: A Retrospective StudyArticle Published on 2020-11-012023-07-12 Journal: Archives of Iranian medicine [Category] SARS, [키워드] COVID – 19 gastrointestinal tract liver pediatric [DOI] 10.34172/aim.2020.104