Should We Be Screening for SARS-CoV-2 in IBD Patients Before Initiation of Biologic Therapy?Editorial Published on 2021-01-192023-06-19 Journal: Inflammatory bowel diseases [Category] MERS, [키워드] biological therapy COVID-19 IBD SARS-CoV-2 [DOI] 10.1093/ibd/izaa173 PMC 바로가기 [Article Type] Editorial
Pediatric inflammatory bowel disease and the effect of COVID-19 pandemic on treatment adherence and patients’ behavior Research Published on 2021-01-142022-10-05 Journal: Pediatric Research [Category] SARS, 치료법, [키워드] activities Affect avoidance Care changed children clinics Complete Compliance concern conducted coronavirus disease COVID-19 COVID-19 pandemic cross-sectional feature Health IBD Impact Infection Inflammatory bowel disease lockdown measure medication Ministry of Health MOST pandemic Patient Pediatric patient Protective questionnaire reported Result Severe COVID-19 Infection the patient Treatment [DOI] 10.1038/s41390-020-01312-6 [Article Type] Research
Down-Regulation of Colonic ACE2 Expression in Patients With Inflammatory Bowel Disease Responding to Anti-TNF Therapy: Implications for COVID-19Medicine Published on 2021-01-122022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] ACE2 ACE2 expression ACE2 protein Active disease alteration analyzed anti-TNFα benefit biologic biopsy change Cohort Colon colonic correlation COVID-19 database determine Disease activity disease course downregulated enzyme II expression GEO database Guangzhou healthy control IBD Immunosuppressive treatment independent Inflammation Inflammatory bowel disease influence information intestinal intestine Mild moderate Necrosis non-responders pathophysiology Patient patients protein expression Responder Responding risk risk of COVID-19 RNA RNA expression SARS-COV-2 infection significantly significantly higher therapy Treatment upregulated [DOI] 10.3389/fmed.2020.613475 PMC 바로가기 [Article Type] Medicine
Intestinal Inflammation Modulates the Expression of ACE2 and TMPRSS2 and Potentially Overlaps With the Pathogenesis of SARS-CoV-2-related Disease장 염증은 ACE2 및 TMPRSS2의 발현을 조절하고 SARS-CoV-2 관련 질병의 발병과 잠재적으로 겹칩니다Article Published on 2021-01-012022-09-11 Journal: Gastroenterology [Category] Fulltext, SARS, 비임상, 임상, 진단, 치료제, [키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition biologic bowel breath brush border confluence coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection defined drug enterocytes expression Gastrointestinal symptom gastrointestinal symptoms generate GI Tract IBD IBD Medications Inflammation Inflammatory bowel disease Intersection intestinal intestinal inflammation intestines large cohort medications molecular network molecular response molecular responses network Network Analyses. Patient receptor Replication respiratory SARS-CoV-2 significantly Stool Support These data TMPRSS2 Treatment treatment of COVID-19 Viral Viral RNA [DOI] 10.1053/j.gastro.2020.09.029 PMC 바로가기 [Article Type] Article
Virus in the pathogenesis of inflammatory bowel disease: role of Toll-like receptor 7/8/3Review Article Published on 2021-01-012022-10-31 Journal: Gastroenterology and Hepatology From Bed to Bench [Category] COVID-19, [키워드] Activation antagonist antiviral immune responses association bowel cause COVID-19 Critical Crohn’s disease dendritic cells effective evaluated expressed finding help IBD IL-1 IL-6 immune system IMPROVE incidence induce Inflammation Inflammatory Inflammatory bowel disease Inflammatory mediators Influenza inhibitors innate immune interferons (IFNs involved less molecular mechanism Pathogenesis Patient patients Quality of life receptor receptors regulate SARS-CoV-2 shown the disease Therapies TLR TLR pathways TLR7 TLR8 TLRs Toll-like receptor Toll-like receptors Treatment ulcerative colitis understanding Vaccine viral infection virus PMC 바로가기 [Article Type] Review Article
Incidence, Clinical Characteristics, and Evolution of SARS-CoV-2 Infection in Patients With Inflammatory Bowel Disease: A Single-Center Study in Madrid, SpainObservational Study Published on 2021-01-012022-10-05 Journal: Inflammatory bowel diseases [Category] 임상, [키워드] 95% CI 95% confidence interval Analysis biologic clinical Clinical course Comorbidities COVID-19 Crohn disease cross-sectional diagnosed diarrhea died disease Dyspnea female greater IBD identify immunomodulator Immunosuppression incidence Infection Inflammatory bowel disease medical record Mild moderate MOST myalgia Odds ratio one patient Patient patient age patients reported SARS-CoV-2 SARS-COV-2 infection Severe infection severity severity of COVID-19 Smokers Spain Symptom the patient therapy treated Treatment World Health Organization [DOI] 10.1093/ibd/izaa221 PMC 바로가기 [Article Type] Observational Study
Severe Enteritis as the Sole Manifestation of Novel Coronavirus Disease 2019 (COVID-19) in Adolescent PatientsCase Report Published on 2020-12-232022-10-31 Journal: Case Reports in Infectious Diseases [Category] COVID-19, [키워드] abdominal pain absence acute respiratory syndrome Adolescent bleeding caused children complications coronavirus Corticosteroid COVID-19 described died Enteritis etiology Evidence feature female healthy highlight Hospitalized IBD Infection Inflammatory Inflammatory bowel disease intravenous male management manifestation Manifestations MIS-C Nasopharyngeal swab novel novel coronavirus disease Patient polymerase chain positive pregnant presenting respiratory symptom reverse transcription RT-PCR SARS-CoV-2 SARS-COV-2 infection Sole syndrome the patient the United State [DOI] 10.1155/2020/8823622 PMC 바로가기 [Article Type] Case Report
Clinical Trials [and Tribulations]: The Immediate Effects of COVID-19 on IBD Clinical Research Activity in the UK임상 시험 [및 고난]: 영국의 IBD 임상 연구 활동에 대한 COVID-19의 즉각적인 영향Article Published on 2020-12-022022-09-11 Journal: Journal of Crohn's & colitis [Category] 임상, [키워드] activity Analysis Care clinical clinical care clinical pathways Clinical research clinical trial clinical trials consequence country COVID-19 Effect effective effort focus Health Health care highlighting IBD Immediate Impact implication management offer pandemic Pathways Patient Perspective Reporting Research Research Ethics Safe SARS-CoV-2 therapeutic option therapy Trial [DOI] 10.1093/ecco-jcc/jjaa137 PMC 바로가기 [Article Type] Article
Expressive writing to combat distress associated with the COVID-19 pandemic in people with inflammatory bowel disease (WriteForIBD): A trial protocolRandomized Controlled Trial Published on 2020-12-012022-10-05 Journal: Journal of psychosomatic research [Category] 임상, [키워드] active control group All participant Analysis bowel carried Complete Complication conducted COVID-19 COVID-19 pandemic COVID-19-related distress Disease activity distress double-blind Effect evaluate expressive Expressive writing help higher risk IBD Immunosuppressive medication Inflammatory bowel disease intention-to-treat basis Intervention linear measure New pandemic participant Patient post-intervention proportion provided Quality of life questionnaire randomised controlled trial receive recruited reduce Registered registry researchers Resilience SARS-CoV-2 SARS-CoV-2 virus Self-efficacy social distancing Support Trial trial protocol [DOI] 10.1016/j.jpsychores.2020.110286 PMC 바로가기 [Article Type] Randomized Controlled Trial
Unraveling the Role of ACE2, the Binding Receptor for SARS-CoV-2, in Inflammatory Bowel DiseaseReview Published on 2020-11-192023-07-12 Journal: Inflammatory bowel diseases [Category] SARS, [키워드] angiotensin-converting enzyme 2 IBD Inflammatory bowel disease integrin signaling SARS-CoV-2 receptor tryptophan absorption. [DOI] 10.1093/ibd/izaa249 PMC 바로가기 [Article Type] Review