SARS-CoV-2 Spike Targets USP33-IRF9 Axis via Exosomal miR-148a to Activate Human Microglia
Immunology
[키워드] addition
Anomaly
association
axis
bystander
catastrophic
CNS
COVID-19
COVID-19 case
declining
deubiquitinase
distress
downstream
dysfunction
Exosome
Exosomes
explain
expression
gene product
Host
Host immune response
Human
Hyperactivation
IFN-β
immune cascade
IRF9
knowledge
microglia
microRNA
modify
mRNA
nervous
Neuroinflammation
neurological
NF-κB
Novel coronavirus infection
organ
pathway
patients
pro-inflammatory gene expression
Protein
provide
regulate
Replication
SARS-CoV-2
shown
Specific
spike
spike gene
supported
suppress
syndrome
System
target
target gene
tissue
TNFα
transfected cell
transported
ubiquitin
uninfected
USP33
Vaccine
Viral load
virus
[DOI] 10.3389/fimmu.2021.656700 PMC 바로가기 [Article Type] Immunology
[DOI] 10.3389/fimmu.2021.656700 PMC 바로가기 [Article Type] Immunology