In silico screening predicts common cold drug Dextromethorphan along with Prednisolone and Dexamethasone can be effective against novel Coronavirus disease (COVID-19)Article Published on 2022-05-012022-10-04 Journal: Journal of biomolecular structure & dynamics [Category] COVID19(2023년), SARS, 신약개발, [키워드] 6LU7 Analysis caused common cold Coronavirus disease 2019 Coronavirus main protease (Mpro) COVID-19 Dexamethasone Dextromethorphan disease docking drug effective Efficacy human-to-human transmission less M pro MERS mortality rate Numerous outbreak patients PDB ID predict Prednisolone protease repurposing researcher synergistic target protein therapy Viral diseases virus [DOI] 10.1080/07391102.2020.1850528 PMC 바로가기 [Article Type] Article
Clinical efficacy and safety of interferon-β-containing regimens in the treatment of patients with COVID-19: a systematic review and meta-analysis of randomized controlled trialsCOVID-19 환자 치료에서 인터페론 베타 함유 요법의 임상 효능 및 안전성: 무작위 대조 시험의 체계적인 검토 및 메타 분석Meta-Analysis Published on 2022-05-012022-09-11 Journal: Expert review of anti-infective therapy [Category] COVID19(2023년), SARS, 임상, 치료제, [키워드] 95% CI Admission adverse event all-cause mortality rate Antiviral treatment benefit clinical Clinical efficacy ClinicalTrials control group control groups Controlled controlled trials COVID-19 Efficacy Efficacy and safety help hospitalized patient hospitalized patients ICU ICU admission IFN-β inception increased risk increased survival intensive care intensive care unit interferon Interferon-β Meta-analysis Mortality mortality rate no significant difference Patient patients with COVID-19 Placebo Randomized Randomized controlled trial RCT RCTs reduce regimen regimens risk Safe SARS-CoV-2 searched serious AE significant difference study group study groups systematic review Treatment with COVID-19 [DOI] 10.1080/14787210.2022.2004118 PMC 바로가기 [Article Type] Meta-Analysis
Clinical and laboratory predictors at ICU admission affecting course of illness and mortality rates in a tertiary COVID-19 center3차 COVID-19 센터의 질병 경과 및 사망률에 영향을 미치는 ICU 입원 시 임상 및 실험실 예측 변수Observational Study Published on 2022-05-012022-09-11 Journal: Heart & lung : the journal of critical care [Category] COVID19(2023년), SARS, 바이오마커, 신약개발, 임상, 치료기술, [키워드] Admission affected affecting age Analysis analyzed applied Arterial hypertension bacterial superinfections baseline clinical clinical feature Clinical features Cohort Comorbidities congestive heart failure Course COVID-19 COVID-19 patient COVID-19 patients Critical care Critically ill critically ill COVID-19 patients Croatia CRP determine Factor Features hospital hypertension ICU ICU admission IL-6 increase Inflammatory biomarker Invasive mechanical ventilation Laboratory laboratory parameter Laboratory parameters Length Mortality mortality rate mortality rates mortality risk multivariate adjustment outcome PaO predict predictor primary endpoint primary endpoints Regression model retrospective risk factor Risk factors Serum ferritin SOFA SOFA score survival survival analysis survival rates Survivors therapeutic intervention therapeutic interventions treated Trial utility [DOI] 10.1016/j.hrtlng.2022.01.013 PMC 바로가기 [Article Type] Observational Study
Can Serum Endocan Levels be Used as an Early Prognostic Marker for Endothelial Dysfunction in COVID-19?혈청 엔도칸 수치를 COVID-19의 내피 기능 장애에 대한 조기 예후 마커로 사용할 수 있습니까?Article Published on 2022-05-012022-09-11 Journal: Angiology [Category] MERS, 바이오마커, [키워드] age blood gas Can Correlation analysis COVID-19 COVID-19 prognosis diagnosis of COVID-19 early stage endocan Endothelial dysfunction female Follow-up group Hospitalized indicated Lactate Level male mortality rate onset of symptom Patient patients Pneumonia positive correlation Prognosis Prognostic marker SARS-CoV-2 serum severe pneumonia the disease Vascular damage venous blood venous blood gas was determined were measured [DOI] 10.1177/00033197211050446 PMC 바로가기 [Article Type] Article
COVID-19 in Children with Cancer and Continuation of Cancer-Directed Therapy During the Infection암에 걸린 어린이의 COVID-19 및 감염 중 암 지향적 치료의 지속Article Published on 2022-05-012022-09-11 Journal: Indian journal of pediatrics [Category] COVID19(2023년), SARS, 치료기술, [키워드] active cancer all-cause mortality rate Cancer Cancer-directed therapy cancers Care Chemotherapy childhood children Children with cancer children with COVID-19 clinically Course COVID-19 COVID-19 related mortality diagnosed with COVID-19 diagnosis of COVID-19 Follow-up India Infection Intensive intravenous median median age Mortality mortality rate Respiratory Support RT-PCR systemic treatment therapy toxicities Treatment with COVID-19 [DOI] 10.1007/s12098-021-03894-3 PMC 바로가기 [Article Type] Article
Euthyroid Sick Syndrome as a Prognostic Indicator of COVID-19 Pulmonary Involvement, Associated With Poorer Disease Prognosis and Increased MortalityResearch article Published on 2022-05-012022-10-05 Journal: Endocrine practice : official journal of the American College of [Category] 바이오마커, [키워드] Admission analyzed association clinical collected Computed tomography Coronavirus disease 2019 (COVID-19) COVID-19 Department diagnosed disease severity enrolled ESS euthyroid sick euthyroid sick syndrome (ESS) High-flow nasal oxygen higher risk Hospitalization hospitalizations Increased indicated Indicator intensive care internal intubation Involvement Kaplan-Meier curve laboratory data lung involvement medical record Mortality mortality rate no difference objective parenchymal Patient patients patients with COVID-19 Pharmacology poor prognosis Prevalence pro-inflammatory probability of survival Prognosis prognostic pulmonary Result subject survival syndrome the patient therapy transfer [DOI] 10.1016/j.eprac.2022.02.006 [Article Type] Research article
Gastrointestinal manifestations of COVID-19 in a single center in the Eastern Province of Saudi ArabiaObservational Study Published on 2022-05-012022-10-04 Journal: Saudi journal of gastroenterology : official journ [Category] COVID19(2023년), SARS, 임상, [키워드] 95% CI abdominal pain acute respiratory distress Altered mental status AOR association conducted COVID-19 COVID-19 infection Cytokine storm syndrome death diarrhea Gastrointestinal gastrointestinal manifestations GI symptom higher risk hospital hospitalized COVID-19 patient less lower mortality lung field lung infiltration manifestation Manifestations Middle East Mortality mortality rate multiorgan failure nausea Novel coronavirus outcome Patient patients PCR test positive Prevalence reported retrospective Saudi Arabia severe COVID-19 disease severity single center Symptom syndrome university hospital vomiting [DOI] 10.4103/sjg.sjg_547_21 PMC 바로가기 [Article Type] Observational Study
A Retrospective Observational Study Exploring 30- and 90-Day Outcomes for Patients With COVID-19 After Percutaneous Tracheostomy and Gastrostomy PlacementObservational Study Published on 2022-05-012022-10-05 Journal: Critical Care Medicine [Category] 임상, [키워드] Boston Clinicians complications COVID-19 COVID-19 patient determine gastrostomy hospitals information measurement Mortality mortality rate outcome Patient patient population patients Percutaneous placement Primary outcome provide receiving secondary tracheostomy [DOI] 10.1097/CCM.0000000000005451 PMC 바로가기 [Article Type] Observational Study
Venous thromboembolism in patients hospitalised with COVID-19 in EnglandObservational Study Published on 2022-05-012022-10-05 Journal: Thrombosis research [Category] 임상, [키워드] 95% confidence interval adjusted Admission Analysis black coronavirus covariates COVID-19 dataset Diagnosis diagnosis of COVID-19 discharge England exploratory Hospital Episode Statistics Hospital stay hospitalisation with COVID-19 hospitalised in-hospital mortality incidence main analysis male mortality rate Observational data Odds ratio over Patient Primary outcome pulmonary Pulmonary embolism recorded Retrospective analysis subsequent Thromboembolism unique Venous Thromboembolism VTE with COVID-19 [DOI] 10.1016/j.thromres.2022.03.017 PMC 바로가기 [Article Type] Observational Study
The phase dynamics of the COVID-19 pandemic: a systematic analysis of 213 Countries and TerritoriesArticle Published on 2022-05-012023-07-09 Journal: Problemy sot︠s︡ialʹnoĭ gigieny, zdravookhranenii︠a︡ i istorii medit︠s︡iny [Category] COVID19(2023년), [키워드] case fatality ratio COVID-19 infection fatality ratio mortality rate phases of the pandemic polymerase chain reaction [DOI] 10.32687/0869-866X-2022-30-3-347-355