plasma sample – Page 14 – Communicable Diseases Research

Recent Advances in the Evaluation of Serological Assays for the Diagnosis of SARS-CoV-2 Infection and COVID-19

SARS-CoV-2 감염 및 COVID-19 진단을 위한 혈청학적 분석 평가의 최근 발전

Public Health

Published on 2021-02-182022-09-11
Journal: Frontiers in Public Health [Category] MERS, SARS, 진단, 치료기술,

SARS-CoV-2 RNA in plasma samples of COVID-19 affected individuals: a cross-sectional proof-of-concept study

COVID-19 영향을 받는 개인의 혈장 샘플에서 SARS-CoV-2 RNA: 횡단면 개념 증명 연구

Research Article

Published on 2021-02-172022-09-01
Journal: BMC Infectious Diseases [Category] MERS, 진단,

[키워드] affected Blood characterized COVID-19 cross-sectional ddPCR develop Fisher exact test haematologic haematological malignancies haematological malignancy help Hematological malignancies higher risk hospital Hospitalized individual IQR laboratory data management median Molecular diagnosis mortality rate outcome Patient patients with COVID-19 plasma plasma sample predict Prognosis quantified Quantitative recent respiratory respiratory sample Respiratory samples Result SARS-CoV-2 SARS-CoV-2 RNA severe COVID-19 significant difference significant differences supplementary material Support variables Viral Viral load Viremia were used Wilcoxon test
[DOI] 10.1186/s12879-021-05886-2 PMC 바로가기 [Article Type] Research Article

Immunoreactive peptide maps of SARS-CoV-2

SARS-CoV-2의 면역반응성 펩타이드 지도

Article

Published on 2021-02-122022-09-12
Journal: Communications Biology [Category] MERS, 진단,

Case Report: Adequate T and B Cell Responses in a SARS-CoV-2 Infected Patient After Immune Checkpoint Inhibition

사례 보고: 면역 체크포인트 억제 후 SARS-CoV-2 감염 환자의 적절한 T 및 B 세포 반응

Case Reports

Published on 2021-02-042022-09-12
Journal: Frontiers in Immunology [Category] MERS, 진단,

Covid-19 Automated Diagnosis and Risk Assessment through Metabolomics and Machine Learning

대사체학 및 기계 학습을 통한 Covid-19 자동 진단 및 위험 평가

Article

Published on 2021-02-022022-09-11
Journal: Analytical Chemistry [Category] MERS, 바이오마커, 치료기술,

[키워드] Algorithm Analysis applied approach assessment assist Biomarker Biomarkers blinded Control COVID-19 COVID-19 diagnosis cross-sectional cross-sectional study Decision-making Diagnostic method elect enrolled equation feature Government Health Healthcare professional healthcare professionals identify impairment Infection introduced machine learning Machine learning algorithms management mass spectrometry metabolite metabolites minutes outcomes pathophysiology Patient Patient management plasma sample plasma samples platform poverty Region reopening resources risk Risk assessment Risk management robustness sensitivity specificity the disease
[DOI] 10.1021/acs.analchem.0c04497 PMC 바로가기 [Article Type] Article

Circulating Markers of Neutrophil Extracellular Traps Are of Prognostic Value in Patients With COVID-19

호중구 세포외 트랩의 순환 마커는 COVID-19 환자에서 예후 가치가 있습니다

Article

Published on 2021-02-012022-09-11
Journal: Arteriosclerosis, Thrombosis, and Vascular Biology [Category] MERS, 바이오마커,

[키워드] acute respiratory distress acute respiratory distress syndrome association Asymptomatic Blood cells C-reactive protein cell-free DNA characterized circulating Clinical outcome Coagulation convalescent plasma coronavirus disease Coronavirus disease 2019 correlated COVID-19 COVID-19 disease COVID-19 disease severity Cytokines declined Disease progression disease severity elevated endothelial damage enrolled evaluate Evidence Extracellular extracellular traps fibrinolysis healthy controls healthy individual healthy individuals histone Hospital admission hyperinflammation immunothrombosis in healthy individual in vivo Infection Inflammation Inflammatory cytokines marker moderate moderate to severe Mortality NET NETs neutrophil Neutrophil elastase Neutrophil extracellular trap Neutrophils pathogenic mechanism pathogenic mechanisms patients with COVID-19 plasma plasma sample plasma samples Post-infection progression respiratory respiratory distress Respiratory distress syndrome Respiratory Support SARS-CoV2 severe disease syndrome target targets therapeutic intervention thrombosis thrombotic thrombotic microangiopathy TRAP value were assessed White blood cells with COVID-19
[DOI] 10.1161/ATVBAHA.120.315267 PMC 바로가기 [Article Type] Article

Increased levels of plasma cytokines and correlations to organ failure and 30-day mortality in critically ill Covid-19 patients

중환자 코로나19 환자의 혈장 사이토카인 수치 증가 및 장기 부전 및 30일 사망률과의 상관관계

Article

Published on 2021-02-012022-09-11
Journal: Cytokine [Category] SARS, 바이오마커,

[키워드] 30-Day mortality abdominal surgery Acute kidney injury Admission Biomarkers Care caused Cohort controls Corona virus correlated correlation COVID-19 Critically ill critically ill COVID-19 patients cytokine cytokine expression cytokine response Cytokine storm Cytokine storm syndrome Cytokines death demonstrated expression IL-17A IL-1ra IL-4 IL-6 IL-8 increase increase in Increased induce Infection Inflammation inflammatory markers inflammatory mediator Inflammatory mediators Inflammatory response Informed consent initial symptoms intensive care IP-10 kidney Kidney injury MCP-1 median mediators moderate Mortality organ damage Organ failure Patient patients PCR-confirmed PCR-confirmed COVID-19 plasma Plasma cytokine plasma sample quantified Respiratory failure SARS CoV SARS CoV-2 SOFA score the strongest was obtained
[DOI] 10.1016/j.cyto.2020.155389 PMC 바로가기 [Article Type] Article

Cell-free DNA tissues of origin by methylation profiling reveals significant cell, tissue, and organ-specific injury related to COVID-19 severity

메틸화 프로파일링에 의한 기원의 무세포 DNA 조직은 COVID-19 중증도와 관련된 중요한 세포, 조직 및 장기 특이적 손상을 나타냅니다

Clinical and Translational Article

Published on 2021-01-162022-09-14
Journal: Med (New York, N.Y.) [Category] MERS, SARS, 유전자 메커니즘, 진단,

[키워드] Abstract advance Affect Award Blood Canada Cell cell-free DNA cfDNA Charle circulating Clinical research Cohort Concentration Context Coronavirus disease 2019 correlated Council COVID-19 COVID-19 patient COVID-19 severity disease Disease progression disease severity DNA DNA profiling Engineering Evidence finding foundation funding healthy controls hospitalized patient hospitalized patients identify independent initiative Injury intubation liquid biopsy liver lung Lungs Medicine Methylation MONITOR NIH organ-specific Patient plasma plasma sample prognostic reveal SARS-CoV-2 Scholar Science severe COVID-19 severe disease significantly increased subject Support supported tissue tissue injury utility viral infection was performed WHO World Health Organization
[DOI] 10.1016/j.medj.2021.01.001 PMC 바로가기 [Article Type] Clinical and Translational Article

Sensitive detection of total anti-Spike antibodies and isotype switching in asymptomatic and symptomatic individuals with COVID-19

COVID-19를 가진 무증상 및 증상이 있는 개인에서 총 항-스파이크 항체 및 이소타입 전환의 민감한 감지

Article

Published on 2021-01-162022-09-10
Journal: Cell Reports Medicine [Category] MERS, 진단, 치료기술,

[키워드] acquisition acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibodies antibody antibody levels Antibody Response Asymptomatic asymptomatic individual Asymptomatic individuals asymptomatic infection asymptomatic infections can be used coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Cytometry detect develop dominant Early detection Flow flow cytometry IgA IgG IgG subclasses IgG1 IgM Immunoglobulin immunoglobulin M individual individuals with COVID-19 Infection infections isotype switching limit plasma sample plasma samples Protein respiratory S protein SARS-CoV-2 sensitive serological serological analysis severe acute respiratory syndrome Coronavirus significantly higher specific antibodies specific antibody specific IgM Spread symptomatic symptomatic and asymptomatic symptomatic individual symptomatic individuals with COVID-19
[DOI] 10.1016/j.xcrm.2021.100193 PMC 바로가기 [Article Type] Article

High prevalence of pre-existing serological cross-reactivity against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in sub-Saharan Africa

사하라 사막 이남 아프리카에서 중증 급성 호흡기 증후군 코로나바이러스-2(SARS-CoV-2)에 대한 기존 혈청학적 교차 반응의 높은 유병률

Article

Published on 2021-01-012022-09-11
Journal: International Journal of Infectious Diseases [Category] MERS, SARS, 진단, 치료기술, 치료법,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 Asia collected Coronavirus-2 correlated COVID-19 COVID-19 pandemic cross-protection cross-reactive cross-reactive antibodies cross-reactive antibody cross-reactivity death disease Europe evaluated exposure to HCoV HCoV-229E HCoV-NL63 HCoVs Human human coronavirus Hypothesis immunofluorescence assay in some incidence Infection morbidity and mortality MOST nucleocapsid protein Nucleocapsid proteins occurred other coronavirus other coronaviruses pandemic Pathogenesis plasma sample plasma samples pre-pandemic plasma sample Pre-pandemic plasma samples Prevalence prevalent Protein Recognition remained respiratory SARS-CoV-2 SARS-COV-2 infection serological serology Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus Significant significantly higher Spike proteins SSA sub-Saharan Africa tested the SARS-CoV-2 the spike protein USA
[DOI] 10.1016/j.ijid.2020.10.104 PMC 바로가기 [Article Type] Article