Phylogeographic investigation of 2014 porcine epidemic diarrhea virus (PEDV) transmission in TaiwanResearch Article Published on 2019-03-062022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, [키워드] absence affecting clinical sample Cluster Clustering collected concentrations correlation database defined dissemination Epidemic epidemic diarrhea Factor GenBank independent Infection outbreak PEDV Phylogenetic S gene sequence sequence information Spread Strains Taiwan Transmission triggered viral strain virus were used [DOI] 10.1371/journal.pone.0213153 PMC 바로가기 [Article Type] Research Article
Whole genome characterisation of quail deltacoronavirus detected in PolandArticle Published on 2019-02-132022-10-28 Journal: Virus Genes [Category] Coronavirus, [키워드] Amino acid C-terminal domain characterisation Deltacoronavirus described full-length genome Genetic characterisation Genome homology identity individual gene isolates membrane fusion middle N-terminal domain nucleotide nucleotide sequence Phylogenetic tree Poland Quail Receptor binding responsible S gene sequence supplementary material the S protein United Arab Emirate variant virus [DOI] 10.1007/s11262-019-01639-1 PMC 바로가기 [Article Type] Article
S1 Subunit of Spike Protein from a Current Highly Virulent Porcine Epidemic Diarrhea Virus Is an Important Determinant of Virulence in PigletsArticle Published on 2018-08-302022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] animal base coronavirus current determinant diarrhea epidemic diarrhea Genes genetics gnotobiotic gnotobiotic piglets high mortality Hypothesis Infection inoculated Japan Japanese Mild North PEDV Porcine epidemic diarrhea virus replaced reverse genetics S gene sequence spike Spike protein Spike proteins strain Symptom the S protein the S1 subunit vaccine candidate virulence virulent virus watery weight loss [DOI] 10.3390/v10090467 PMC 바로가기 [Article Type] Article
The S2 Subunit of Infectious Bronchitis Virus Beaudette Is a Determinant of Cellular TropismVirus-Cell Interactions Published on 2018-07-182022-10-30 Journal: Journal of Virology [Category] Coronavirus, MERS, [키워드] Amino acid avirulent bronchitis Cell cell tropism cellular tropism chick chimeric Combination coronavirus cultured cell cultured cells demonstrated determinant determine ectodomain Effective vaccines expressing genetics genomic glycoprotein growth IBV in vitro in vivo inactivated Infectious Bronchitis Virus information introduced involved kidney M41 observation primary cell produced progeny Region replicate responsible reverse genetic analysis S gene S glycoprotein S glycoproteins S1 and S2 S2 subunit S2′ S2′ cleavage strain subunit tropism Vaccine Vaccines Vero Cell Vero cells virulence virulent virus [DOI] 10.1128/JVI.01044-18 PMC 바로가기 [Article Type] Virus-Cell Interactions
Molecular characterization of US-like and Asian non-S INDEL strains of porcine epidemic diarrhea virus (PEDV) that circulated in Japan during 2013–2016 and PEDVs collected from recurrent outbreaksResearch Article Published on 2018-03-142022-10-28 Journal: BMC veterinary research [Category] Coronavirus, [키워드] affected Analysis analyzed ancestor antigenicity Asian caused changes in Characteristics circulating classical collected comparison develop Efficacy Endemic epidemic diarrhea Epidemics epitope full-length Genetic genetic heterogeneity glycosylation help introduced Japan Japanese Local M gene measure membrane Molecular epidemiology N gene North nucleocapsid outbreak Outbreaks parental PEDV phosphorylation sites Porcine epidemic diarrhea virus Proteins provide Region regions responsible Result resulting S gene sequence sequenced spike gene strain Strains subsequent substitutions suggested supplementary material the disease Vaccine vaccine strain virus [DOI] 10.1186/s12917-018-1409-0 PMC 바로가기 [Article Type] Research Article
Antigenicity reduction contributes mostly to poor detectability of HBsAg by hepatitis B virus (HBV) S-gene mutants isolated from individuals with occult HBV infectionArticle Published on 2018-02-012023-06-19 Journal: Journal of medical virology [Category] B형 간염, [키워드] antigenicity Hepatitis B virus Mutation occult HBV infection S gene [DOI] 10.1002/jmv.24936
Epidemiology characteristics of human coronaviruses in patients with respiratory infection symptoms and phylogenetic analysis of HCoV-OC43 during 2010-2015 in GuangzhouResearch Article Published on 2018-01-292022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] 229E age cause Characteristics children China Cluster co-infecting collected coronavirus defined detection rate distribution dominant Epidemic epidemiological feature Fever Genetic variation Genotype group Guangzhou HCoV-OC43 high risk HKU1 Human human coronavirus Influenza virus Inpatient Malaysia nasal swab NL63 OC43 Patient PCR Phylogenetic analysis Phylogenetic tree positive positive patients positive sample prevalent Real-time PCR real-time RT-PCR respiratory infection respiratory tract infection respiratory virus respiratory viruses S gene screened selected Sequencing specimen strain Symptom tested upper respiratory infection virus [DOI] 10.1371/journal.pone.0191789 PMC 바로가기 [Article Type] Research Article
Hepatitis B virus vaccine breakthrough infection: surveillance of S gene mutants of HBVReview Published on 2018-01-012023-06-16 Journal: Acta virologica [Category] B형 간염, [키워드] HBV vaccine breakthrough infection mutants S gene Surveillance [DOI] 10.4149/av_2018_210 [Article Type] Review
Tracking the Origin and Deciphering the Phylogenetic Relationship of Porcine Epidemic Diarrhea Virus in EcuadorResearch Article Published on 2017-12-122022-10-27 Journal: BioMed Research International [Category] Coronavirus, MERS, [키워드] Analysis Bayesian Canada China Chinese clade classical clinically comparison Complete conducted Ecuador epidemic diarrhea GenBank database isolate origin PEDV relationship S gene sequence spread to strain Strains suggested Transmission United State United States virus [DOI] 10.1155/2017/2978718 PMC 바로가기 [Article Type] Research Article
Discovery of a rich gene pool of bat SARS-related coronaviruses provides new insights into the origin of SARS coronavirusResearch Article Published on 2017-11-302022-10-29 Journal: PLoS Pathogens [Category] Coronavirus, MERS, [키워드] ACE2 addition Analysis bat block cave cell entry China circulating demonstrated Diseases domain Evidence Evolution exhibiting full-length genome full-length genome sequence Genetic Genome highlight Host Human human ACE2 Increasing N-terminal domain non-structural protein NTD offer ORF1a ORF3 ORF3b ORF8 ORF8a precursor provide RBD receptor recombination event reveal risk S gene S protein SARS Coronavirus SARS-CoV SARS-related coronavirus SARSr-CoV SARSr-CoVs sequence similarity strain Strains Support Surveillance thought Transmission unlikely [DOI] 10.1371/journal.ppat.1006698 PMC 바로가기 [Article Type] Research Article