SARS-CoV-2 strain – Page 14 – Communicable Diseases Research

Characterization of SARS-CoV-2 worldwide transmission based on evolutionary dynamics and specific viral mutations in the spike protein

스파이크 단백질의 진화 역학 및 특정 바이러스 돌연변이를 기반으로 한 SARS-CoV-2 전 세계 전파 특성

Research Article

Published on 2021-08-212022-09-10
Journal: Infectious Diseases of Poverty [Category] MERS, SARS, 변종, 진단,

Effect of SARS-CoV-2 Mutations on the Efficacy of Antibody Therapy and Response to Vaccines

Review

Published on 2021-08-172022-10-28
Journal: Vaccines [Category] COVID-19,

Potent prophylactic and therapeutic efficacy of recombinant human ACE2-Fc against SARS-CoV-2 infection in vivo

Article

Published on 2021-08-122022-10-04
Journal: Cell Discovery [Category] 변종, 치료제,

[키워드] ACE2 ACE2-Fc addition antiviral effects B.1.1.7 B.1.351 B.1.617.1 B.1.617.2 Beta bind blocked catalytic activity caused COVID-19 pandemic D614G Delta dose-dependent efficacy entry of SARS-CoV-2 enzyme escape mutants functional fusion protein hACE2 hACE2-expressing cell HCoV-NL63 histological changes immunology in vivo indicated induce infections Inflammation inhibited Lungs Mechanisms of disease mice mutant mutations neutralized Neutralizing antibodies potent Prophylactic prophylactic treatment Prophylaxis Protein provided public health threat RBD receptor Receptor binding domain reduced SARS-CoV SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 S SARS-CoV-2 spike protein SARS-CoV-2 strain SARS-CoV-2 variants soluble ACE2 therapeutic therapeutic efficacy therapy for COVID-19 Treatment V367F viral replication weight loss
[DOI] 10.1038/s41421-021-00302-0 PMC 바로가기 [Article Type] Article

Whole-Genome Sequences of SARS-CoV-2 Lineage B.1.525 Strains (Variant η) Detected from Patients in the Abruzzo Region (Central Italy) during Spring 2021

Genome Sequences

Published on 2021-08-052022-10-29
Journal: Microbiology Resource Announcements [Category] COVID-19,

[키워드] Abruzzo acute respiratory syndrome B.1.525 Complete coronavirus genome sequence Italy Lineage novel Region SARS-CoV-2 SARS-CoV-2 strain sequence spring strain variant
[DOI] 10.1128/MRA.00618-21 PMC 바로가기 [Article Type] Genome Sequences

COVID-19 Cases from the First Local Outbreak of the SARS-CoV-2 B.1.1.7 Variant in China May Present More Serious Clinical Features: A Prospective, Comparative Cohort Study

SARS-CoV-2 B.1.1.7 변종 중국의 첫 번째 지역 발병으로 인한 COVID-19 사례가 더 심각한 임상 특징을 나타낼 수 있음: 전향적, 비교 코호트 연구

Research Article

Published on 2021-08-042022-09-10
Journal: Microbiology Spectrum [Category] MERS, SARS, 변종, 치료기술, 치료제,

[키워드] acute response age amyloid A B.1.1.7 B.1.1.7 variant Beijing C-reactive protein caused CD4 China clinical Clinical characteristics clinical feature Clinical features Clinical tests Comparative conducted contagious COVID-19 COVID-19 case COVID-19 cases COVID-19 outbreak COVID-19 patient COVID-19 patients creatine creatine kinase CRP d -dimer database diagnoses dimer District elevated Epidemics Features Fever GGO ground-glass opacity Infection Inflammatory response knowledge lead lung Lymphocytes median N gene occurred outbreak p value p values pathogenicity Pneumonia present proportion Prospective quantitative PCR reported reverse transcriptase risk factor RT-qPCR SAA SARS-CoV-2 SARS-CoV-2 B.1.1.7 SARS-CoV-2 strain serum amyloid severe pneumonia significantly higher significantly lower T lymphocyte T lymphocytes The B.1.1.7 the SARS-CoV-2 threshold transcriptase Transmission triggered United Kingdom variant Viral Viral load viral loads whole-genome analysis
[DOI] 10.1128/Spectrum.00273-21 PMC 바로가기 [Article Type] Research Article

Overlapping of Independent SARS-CoV-2 Nosocomial Transmissions in a Complex Outbreak

Research Article

Published on 2021-08-042022-10-30
Journal: mSphere [Category] COVID-19, MERS, SARS,

[키워드] Analysis assumption Care carried caused clinician Clusters complex COVID-19 discriminatory power epidemiological epidemiological finding Fatality rate FIVE gastroenterology Genomic epidemiology Health health care workers homogeneous hospital in-depth analysis independent indication infecting Infection initial Initially involved limitations Measures nosocomial nosocomial COVID-19 nosocomial outbreak Nosocomial transmission occurred offered outbreak overlapping Patient Personal protective equipment Perspective required SARS-CoV-2 SARS-CoV-2 strain second wave secondary case Sequencing severity strain Strains the SARS-CoV-2 Transmission transmission cluster virulent WGS
[DOI] 10.1128/mSphere.00389-21 PMC 바로가기 [Article Type] Research Article

Catching SARS-CoV-2 by Sequence Hybridization: a Comparative Analysis

Research Article

Published on 2021-08-032022-10-29
Journal: mSystems [Category] COVID-19,

[키워드] acute respiratory syndrome adaptive mutations approach approaches Bioscience circulating Community Comparative computation condition controlling coronavirus ddPCR determine digital PCR Efficiency efficient enrichment evaluate Evolution FIVE flow cell full-length genome Genome geographical distribution Illumina improvement Laboratory MONITOR Multiplex PCR Mutation mutations Next-generation sequencing NGS pandemic question resources SARS-CoV-2 SARS-CoV-2 sequencing SARS-CoV-2 strain sensitivity sequence sequence capture Sequencing the patient the SARS-CoV-2 virus Twist viral spread virus
[DOI] 10.1128/mSystems.00392-21 PMC 바로가기 [Article Type] Research Article

Differential serological and neutralizing antibody dynamics after an infection by a single SARS-CoV-2 strain

단일 SARS-CoV-2 균주에 의한 감염 후 차등 혈청학적 및 중화 항체 역학

Case Reports

Published on 2021-08-012022-09-12
Journal: Infection [Category] MERS, SARS, 진단,

Molecular epidemiology analysis of early variants of SARS-CoV-2 reveals the potential impact of mutations P504L and Y541C (NSP13) in the clinical COVID-19 outcomes

SARS-CoV-2의 초기 변이체에 대한 분자 역학 분석은 임상 COVID-19 결과에서 돌연변이 P504L 및 Y541C(NSP13)의 잠재적 영향을 보여줍니다

Article

Published on 2021-08-012022-09-11
Journal: Infection, genetics and evolution : journal of mol [Category] SARS, 변종, 치료기술,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition aggregation Amino acid Amino acid variations Analysis analyzed Canada caused Characteristics clade contribute coronavirus country COVID-19 death demonstrated detect Effect Epidemiology Evolution Fatality rate feature functional Genetic variation Genetic variations Genome Genotype global pandemic identify Infection involved Mutation nonsynonymous nsp13 ORF1 ORF1ab outcome outcomes performed Phylogenetic analysis Phylogenetic tree Prevent proportion Report date Result reveal SARS-CoV-2 SARS-CoV-2 strain SARS-CoV-2 strains SARS-CoV-2 strains. sequence Sequence alignment severe acute respiratory syndrome Coronavirus state strain Strains the United State The United States United States variant variants variants of SARS-CoV-2 Variation variations virus Washington
[DOI] 10.1016/j.meegid.2021.104831 PMC 바로가기 [Article Type] Article

Assessment of basic reproduction number (R 0), spatial and temporal epidemiological determinants, and genetic characterization of SARS-CoV-2 in Bangladesh

방글라데시 SARS-CoV-2의 기본 생식 수(R 0), 공간 및 시간 역학 결정인자 및 유전적 특성 평가

Article

Published on 2021-08-012022-09-11
Journal: Infection, genetics and evolution : journal of mol [Category] SARS, 변종, 치료기술, 치료법,

[키워드] Analysis assessment B.1 B.1.1 basic reproduction number calculated Case fatality rate circulating clade Cluster continuous monitoring country COVID-19 cumulative D614G detect determinants distribution effective Effectiveness epidemiological evaluate exponential growth Fatality rate Genetic Genome genomic Genomic analysis Genomic surveillance highest incidence of COVID-19 Infection isolates Lineage Local molecular molecular characteristics Molecular epidemiology Mutation Non-synonymous NSP11 NSP2 Nsp9 nucleocapsid nucleocapsid protein P323L pandemic Pangolin lineage performed Phylogenetic Phylogenetic analysis prediction predominant projection Protein RdRP SARS-CoV-2 SARS-CoV-2 sequence SARS-CoV-2 sequences SARS-CoV-2 strain sequence spike Spread strain Strains subsequent Surveillance Transmission dynamics unique vaccination variants of SARS-CoV-2 variations virus was recorded were recorded
[DOI] 10.1016/j.meegid.2021.104884 PMC 바로가기 [Article Type] Article