Comparison of IgA, IgG, and Neutralizing Antibody Responses Following Immunization With Moderna, BioNTech, AstraZeneca, Sputnik-V, Johnson and Johnson, and Sinopharm’s COVID-19 VaccinesModerna, BioNTech, AstraZeneca, Sputnik-V, Johnson and Johnson 및 Sinopharm의 COVID-19 백신을 사용한 면역 후 IgA, IgG 및 중화 항체 반응의 비교Article Published on 2022-06-212022-09-12 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] age Analysis analyzed antibody Antibody titers AstraZeneca automated binding blood sample categories category Combination comparable Correlation analysis COVID-19 COVID-19 vaccines demonstrated DNA dose doses effective ELISA expression group groups Heterologous highest homologous IgA IgG immunogenic investigated lowest moderate Moderna mRNA vaccine negative correlation neutralization Neutralizing Neutralizing antibodies neutralizing antibody Older reactogenicity response sandwich ELISA SARS-CoV-2 sera significant increase significantly higher Sinopharm Spearman specific neutralizing antibody statistically Trial vaccination Vaccination strategy Vaccine vaccinee vaccinees vectored vaccine virus Virus neutralization Virus-specific IgG Volunteer [DOI] 10.3389/fimmu.2022.917905 PMC 바로가기 [Article Type] Article
Absence of neutralizing antibodies against the Omicron SARS-CoV-2 variant in convalescent sera from individuals infected with the ancestral SARS-CoV-2 virus or its Gamma variantArticle Published on 2022-06-162022-11-15 Journal: Clinics [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] antibody convalescent sera dominant effective evaluate Gamma Gamma variant Hospitalization in vitro individual individuals Infection Mild moderate Neutralizing antibodies neutralizing antibody Neutralizing antibody response omicron Omicron variant pandemic positive Protective protective antibodies SARS-CoV-2 SARS-CoV-2 vaccine SARS-CoV-2 variant SARS-CoV-2 virus sera serum strain Symptom the SARS-CoV-2 variant variants [DOI] 10.1016/j.clinsp.2022.100068 PMC 바로가기
Decay of anti-Bordetella pertussis antibodies in women of childbearing age following COVID-19 non-pharmaceutical measuresCOVID-19 비약물적 조치에 따른 가임기 여성의 항보르데텔라 백일해 항체 붕괴Article Published on 2022-06-152022-09-12 Journal: Vaccine [Category] MERS, 백일해, 진단, [키워드] 95% CI Annual Antenatal immunization antibody assigned blood sample Bonferroni correction Bordetella pertussis Canada changed childbearing age collected Coronavirus disease 2019 COVID-19 COVID-19 pandemic decay declined female gestation healthy IgG IgG level IgG levels Immunity Immunoglobulin G implementation incidence Infant Infection Level lowest measure morbidity P-value pertussis Pregnancy pregnant women reduce reflected reported respiratory pathogen sera significantly statistical significance t tests tested transfer women [DOI] 10.1016/j.vaccine.2022.04.086 PMC 바로가기 [Article Type] Article
Functional properties of the spike glycoprotein of the emerging SARS-CoV-2 variant B.1.1.529신흥 SARS-CoV-2 변이체 B.1.1.529의 스파이크 당단백질의 기능적 특성Article Published on 2022-06-142022-09-11 Journal: Cell Reports [Category] COVID19(2023년), SARS, 변종, [키워드] ACE2 ACE2 affinity ACE2 binding acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 B.1.1.529 B.1.617.2 Cell coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 CP: Immunology CP: Microbiology cytopathic effects D614G decrease exhibit functional glycoprotein higher affinity immune evasion immunology Infection less Microbiology neutralization neutralization sensitivity omicron Patient prevalent processing property pseudovirus pseudoviruses relative S glycoprotein S glycoproteins S trimer S1 shedding SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants sera severe acute respiratory syndrome Coronavirus spike glycoprotein stability syncytium formation temperature TMPRSS2 TMPRSS2 expression Transmission unliganded vaccinees variant variants virion [DOI] 10.1016/j.celrep.2022.110924 PMC 바로가기 [Article Type] Article
Neutralising reactivity against SARS-CoV-2 Delta and Omicron variants by vaccination and infection history백신 접종 및 감염 이력에 의한 SARS-CoV-2 Delta 및 Omicron 변이체에 대한 반응성 중화Article Published on 2022-06-102022-09-11 Journal: Genome Medicine [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료법, [키워드] Abbott anti-S antibody antibody antibody persistence Antibody Response Antibody titre antibody titres Antigen B.1 B.1.1.529 B.1.617.2 blood sample Blood samples Cohort collected control group control groups controls COVID-19 cross-protective Delta delta variant DiaSorin dose elicited followed by generate group healthcare healthcare worker Immune escape Immunity immunoassays increasingly individuals induce Infection investigated N antigen naïve naïve subject naïve subjects natural infection neutralisation neutralising Neutralising Antibodies nucleocapsid omicron Omicron variant performed persistence Post-infection presence of antibody question reactivity required Roche S antigen SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2 strain SARS-CoV-2 variant SARS-CoV-2 variants sera Serosurvey serum significantly subject subjects tested the SARS-CoV-2 timepoints two groups vaccinated individuals vaccination Vaccine Vaccine development variant virus VoC VOCs weakened were used while [DOI] 10.1186/s13073-022-01066-2 PMC 바로가기 [Article Type] Article
Immunogenicity of convalescent and vaccinated sera against clinical isolates of ancestral SARS-CoV-2, Beta, Delta, and Omicron variants조상 SARS-CoV-2, 베타, 델타 및 오미크론 변이체의 임상 분리주에 대한 회복기 및 백신 접종 혈청의 면역원성Article Published on 2022-06-102022-09-11 Journal: Med (New York, N.Y.) [Category] COVID19(2023년), MERS, SARS, 변종, 임상, 진단, [키워드] antibody Antibody titers Beta booster vaccination Canada CL3 clinical isolates convalescent convalescent individual convalescent individuals convalescent sera coronavirus coronavirus disease COVID-19 Delta delta variant demonstrated dose foundation Government immunogenicity individual induce initiative Innovation isolate long-term Major microneutralization Ministry of Agriculture Moderna multiple mutation multiple mutations neutralization Neutralizing Neutralizing activity Neutralizing antibodies neutralizing antibody Neutralizing antibody titer omicron Omicron variant Pfizer raising receive recipient reduced Research SARS-CoV-2 Science sera significantly higher Spike protein the spike protein vaccinated individual vaccinated individuals Vaccine variant variants variants of concern VIDO virus VoC VOCs [DOI] 10.1016/j.medj.2022.04.002 PMC 바로가기 [Article Type] Article
Proper Selection of In Vitro Cell Model Affects the Characterization of the Neutralizing Antibody Response against SARS-CoV-2체외 세포 모델의 적절한 선택은 SARS-CoV-2에 대한 중화 항체 반응의 특성화에 영향을 미칩니다Article Published on 2022-06-072022-09-11 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] antibody Antibody Response BNT162b2 BNT162b2 mRNA BNT162b2 mRNA vaccine Calu Calu-3 cell line cell lines cellular characterization characterized choice collected correlation COVID-19 COVID-19 vaccine Cytopathic effect cytopathic effects demonstrated Entry mechanism entry mechanisms evaluated in vitro increasingly inhibitory activity lack mechanisms Model mRNA mRNA vaccine natural infection Neutralizing Neutralizing activity occur of BNT162b2 PCR pseudovirus pseudoviruses response SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variants SARS-CoV-2 viral Selection sera Single Cell subject Surrogates TMPRSS2 vaccine-induced antibodies vaccine-induced antibody variants Vero Vero E6 Viral viral entry viral entry pathway virus particles VOCs [DOI] 10.3390/v14061232 PMC 바로가기 [Article Type] Article
Elevated neutralization of Omicron with sera of COVID-19 recovered and breakthrough cases vaccinated with Covaxin than two dose naïve vaccineesCOVID-19의 혈청으로 Omicron의 중화 증가 및 Covaxin으로 예방 접종을 받은 획기적인 사례는 2회 용량의 순진한 백신보다Article Published on 2022-06-012022-09-12 Journal: The Journal of Infection [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] Abstract breakthrough Covaxin COVID-19 dose IgG IgG antibodies naïve vaccinee neutralization omicron SARS-CoV-2 sera [DOI] 10.1016/j.jinf.2022.03.016 PMC 바로가기 [Article Type] Article
Long-term immunity in convalescent Syrian hamsters provides protection against new-variant SARS-CoV-2 infection of the lower but not upper respiratory tract회복기 시리안 햄스터의 장기 면역은 상부 호흡기가 아닌 하부 호흡기의 새로운 변종 SARS-CoV-2 감염에 대한 보호를 제공합니다Article Published on 2022-06-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory syndrome alpha and delta variants Breakthrough infection breakthrough infections circulating antibodies circulating antibody convalescent coronavirus coronavirus 2 COVID-19 delta variant effective hamster Hospitalization immune patients Immunity Infection Infectious virus infectious viruses less long-term immunity Lower respiratory tract Preexisting immunity provide Reinfection Replication SARS-CoV-2 SARS-COV-2 infection sera Severe acute respiratory syndrome Severe acute respiratory syndrome-related coronavirus severe acute respiratory syndrome-related coronavirus 2 severe disease shedding upper respiratory tract Vaccine variants variants of concern [DOI] 10.1002/jmv.27641 PMC 바로가기 [Article Type] Article
Assessment of BIV1-CovIran inactivated vaccine-elicited neutralizing antibody against the emerging SARS-CoV-2 variants of concern우려되는 신종 SARS-CoV-2 변이체에 대한 BIV1-CovIran 비활성화 백신 유도 중화 항체 평가Article Published on 2022-06-012022-09-11 Journal: Clinical microbiology and infection : the official [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] Alpha antibody assessment B.1.1.7 B.1.351 B.1.617.2 Beta binding domain BIV1-CovIran vaccine candidate vaccine conventional virus neutralization test correlated correlation COVID-19 COVID-19 vaccine Delta delta variant Delta variants demonstrated effective exhibited inactivated individual investigated NAb NAbs neutralization neutralization test neutralize Neutralizing Neutralizing activity Neutralizing antibodies neutralizing antibody Protein recipient recipients reduction in SARS-CoV-2 SARS-CoV-2 strain SARS-CoV-2 vaccine SARS-CoV-2 variant SARS-CoV-2 variants sensitivity sera serum Spearman the SARS-CoV-2 titre Vaccine vaccinee vaccinees variant variants variants of concern virus neutralization test virus-neutralizing was measured Wuhan strain [DOI] 10.1016/j.cmi.2022.02.030 PMC 바로가기 [Article Type] Article