Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study
COVID-19로 입원한 성인을 위한 ISARIC 4C 악화 모델의 개발 및 검증: 전향적 코호트 연구
Multicenter Study
Published on
Journal: The Lancet. Respiratory Medicine [Category] Communicable Disease, MERS, SARS, 진단,
Journal: The Lancet. Respiratory Medicine [Category] Communicable Disease, MERS, SARS, 진단,
[키워드] 4C Deterioration model
74 944 participant
acute COVID-19
Against
benefit
Biomarker
C-statistic
calibration
calibration slope
calibration-in-the-large
candidate
clinical
Clinical deterioration
clinical deterioration outcome
Clinical management
clinical utility
Cohort
coronavirus
COVID-19
Critical care
death
Decision making
defined
Department
development
discrimination
eight
England
European
evaluate
Final
finding
for inclusion
foundation
funding
generalisability
greater
health protection
hospital
Hospital admission
hospitalised
Imperial College London
In-hospital
internal–external cross-validation
ISARIC 4C
ISARIC4C
London
Medical Research Council
Melinda Gate
Melinda Gates
multivariable logistic regression
multivariable logistic regression model
National Health Service
NHS
NIHR
NIHR HPRU
outcome
Participants
predict
predictor
Prognosis
prognostic
prognostic model
prospective cohort study
protection
recruited
Region
regions
required
respiratory
respiratory infections
risk
the selected model
unit
University of Liverpool
ventilatory support
Wellcome Trust
with COVID-19
zoonotic infections
[DOI] 10.1016/S2213-2600(20)30559-2 PMC 바로가기 [Article Type] Multicenter Study
[DOI] 10.1016/S2213-2600(20)30559-2 PMC 바로가기 [Article Type] Multicenter Study