Deep sequencing of HBV pre-S region reveals high heterogeneity of HBV genotypes and associations of word pattern frequencies with HCCHBV pre-S 영역의 심층 시퀀싱은 HBV 유전자형의 높은 이질성과 HCC와 단어 패턴 빈도의 연관성을 보여줍니다Research Article Published on 2018-02-232022-09-06 Journal: PLoS Genetics [Category] B형 간염, Communicable Disease, [키워드] Accuracy Analysis approach approaches association AUC build calculated can be used characteristic CHB China Classifier Clustering Complication Cross-validation data set deep followed by fraction Frequency Genotype group HBV HBV infection HCC HCC patient hepatitis B Hepatitis B virus Hepatocellular carcinoma heterogeneity Hierarchical hierarchical clustering high accuracy High-throughput sequencing include independent data set individual individuals infected individual infected individuals Infection information lead liver Liver cancer Manhattan distance MDs next generation sequencing NGS predict prevalent Probability regions reveal Sanger sequencing second sequence sequences Sequencing shown significantly Support support vector machine SVM virus was obtained [DOI] 10.1371/journal.pgen.1007206 PMC 바로가기 [Article Type] Research Article
Inferring the hosts of coronavirus using dual statistical models based on nucleotide compositionArticle Published on 2015-11-262022-10-29 Journal: Scientific Reports [Category] Coronavirus, MERS, [키워드] acute respiratory syndrome approach caused coronavirus Coronaviruses high accuracy Host human pathogen humans MERS-CoV Middle East nucleotide Panic parameter prediction researchers respiratory syndrome coronavirus SARS-CoV spike gene statistical model Support SVM training data Transmission [DOI] 10.1038/srep17155 PMC 바로가기 [Article Type] Article
Detection of swine transmissible gastroenteritis coronavirus using loop-mediated isothermal amplificationResearch Published on 2010-08-292022-10-28 Journal: Virology Journal [Category] Coronavirus, MERS, [키워드] comparable conserved coronavirus detect detection Detection limit digestion Dilution found gastroenteritis high accuracy isothermal amplification Loop-mediated isothermal amplification nucleic acid Nucleocapsid gene PCR primer RNA specificity Standard TGEV viruses [DOI] 10.1186/1743-422X-7-206 PMC 바로가기 [Article Type] Research