Anti-inflammatory microRNA-146a protects mice from diet-induced metabolic disease
항염증성 microRNA-146a는 식이 유발 대사 질환으로부터 생쥐를 보호합니다
Research Article
[키워드] absence
adipose
Adipose tissue
Adiposity
administration
blockade
blood glucose
cellular
cellular metabolism
cellular respiration
chronic inflammation
Combination
contribute
Control
controls
creating
Critical
demonstrated
develop
Diabetic
diabetic patient
diabetic patients
diet
dysregulated
Evidence
expressed
expression
Factor
fat
genetics
Glucose
Glycolysis
Human
identifying
Immune cell
immune cells
increase in
Inflammation
inflammatory function
inflammatory gene
inflammatory genes
inflammatory pathways
influence
inhibitor
Interaction
investigated
involved
Macrophage
macrophages
mechanism
metabolic disease
metabolic pathway
metabolic pathways
metabolic processe
metabolic processes
metabolism
mice
microRNA
miR-146
miRNA
mTOR
NF-κB
NF-κB activation
obese
obesity
pathway
phenotype
Phenotypes
potential therapeutic target
Prevent
Pro-inflammatory genes
PROTECT
protective role
provide
Rapamycin
reduced
regulate
regulated
Regulatory
represse
Research
RNA-sequencing
shown
Symptom
tissue
tissue macrophage
Traf6
weight gain
wild-type
[DOI] 10.1371/journal.pgen.1007970 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1371/journal.pgen.1007970 PMC 바로가기 [Article Type] Research Article