pro-inflammatory cytokine – Page 15 – Communicable Diseases Research

Granulocyte macrophage colony-stimulating factor has come of age: From a vaccine adjuvant to antiviral immunotherapy

과립구 대식세포 집락 자극 인자가 도래했다: 백신 보조제에서 항바이러스 면역요법까지

Review

Published on 2021-06-012022-09-11
Journal: Cytokine & growth factor reviews [Category] SARS, 치료제,

Infection-Mediated Clinical Biomarkers for a COVID-19 Electrical Biosensing Platform

COVID-19 전기 바이오센싱 플랫폼을 위한 감염 매개 임상 바이오마커

Review

Published on 2021-06-012022-09-10
Journal: Sensors (Basel, Switzerland) [Category] MERS, SARS, 바이오마커, 치료기술,

[키워드] acute phase acute phase proteins adjunct diagnostic biomarkers AIDS Biomarker Biomarkers clinical Clinical studies clinical study coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 diagnosis CT scan CT scans Cytokine storm Cytokines diagnosing Diagnosis diagnostic drug effective effort electrical electrochemical sensors electronic biosensors focus Healthcare system Healthcare systems implementation infected patient infected patients limitation pandemic pro-inflammatory cytokine pro-inflammatory cytokines Prognosis prognostic prognostic indicators Proteins provided researcher RT-PCR secretion severity the disease Vaccines with COVID-19
[DOI] 10.3390/s21113829 PMC 바로가기 [Article Type] Review

Macrophages and Dendritic Cells Are Not the Major Source of Pro-Inflammatory Cytokines Upon SARS-CoV-2 Infection

SARS-CoV-2 감염 시 대식세포와 수지상 세포는 염증 유발 사이토카인의 주요 공급원이 아닙니다

Immunology

Published on 2021-05-262022-09-11
Journal: Frontiers in Immunology [Category] MERS, SARS, 바이오마커,

[키워드] Activation activation status acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 changes in Co-infection Corona virus coronavirus COVID-19 cytokine Cytokine storm Cytokines dendritic cell dendritic cells disease experiment First wave flu IL-6 immune cells in vitro Infection infection with SARS-CoV-2 Influenza influenza A innate immune cell Innate immune cells interferon interleukin 6 M2 macrophage M2 macrophages Macrophage macrophages Major Necrosis pro-inflammatory cytokine pro-inflammatory cytokines produced respiratory SARS-CoV-2 severe acute respiratory syndrome Coronavirus Source susceptible Tumor tumor necrosis tumor necrosis factor tumor necrosis factor alpha/TNF-alpha type I interferon unlikely viruses
[DOI] 10.3389/fimmu.2021.647824 PMC 바로가기 [Article Type] Immunology

The Therapeutic Effect of Traditional Chinese Medicine on Inflammatory Diseases Caused by Virus, Especially on Those Caused by COVID-19

Pharmacology

Published on 2021-05-262022-10-31
Journal: Frontiers in Pharmacology [Category] COVID-19,

Comparing infectivity and virulence of emerging SARS-CoV-2 variants in Syrian hamsters

시리아 햄스터의 신종 SARS-CoV-2 변이체의 감염력 및 독성 비교

Comparative Study

Published on 2021-05-252022-09-11
Journal: EBioMedicine [Category] MERS, SARS, 변종, 진단, 치료기술,

[키워드] African Analysis antibodies Antiviral B.1.1.28.1 B.1.1.7 B.1.351 B.1.351 variant B.1.351 variants Candidates clinical evidence COVID-19 cytokine Cytokines disease dominant Efficacy emergence Epidemics expression profile expression profiles female finding funding Genes golden hamsters hamster Hamster model hamsters histological Infection Lower respiratory tract New outcome Patient pro-inflammatory cytokine Proinflammatory cytokine proinflammatory cytokines quantified relative infectivity replacing respiratory SARS-CoV-2 SARS-CoV-2 strain SARS-CoV-2 variant selected Small molecules South strain Strains Syrian golden hamster tomography transmitted United Kingdom Vaccine-induced immunity variants variants of concern (VOC) virulence virulent
[DOI] 10.1016/j.ebiom.2021.103403 PMC 바로가기 [Article Type] Comparative Study

Type I and III IFNs produced by the nasal epithelia and dimmed inflammation are features of alpacas resolving MERS-CoV infection

Research Article

Published on 2021-05-242022-10-29
Journal: PLoS Pathogens [Category] COVID-19,

[키워드] Adaptive immune response anti-inflammatory cytokine anti-inflammatory effect antiviral drug Asymptomatic Asymptomatic carriers CCL2 CCL3 chemokine clearance clinical manifestation Concomitant contribute correlated Cytokine storm disease driving effective elicited epithelia etiological agent expression feature high mortality Host humans IFN IL10 immune response gene immunological pathway Infection Infectious virus infiltration Inflammation Inflammatory responses innate immune response interferon interferon response interferons (IFNs ISG ISGs lethal disease leukocyte leukocytes lung MERS-CoV MERS-CoV infection Middle East Mild mucosa nasal nasal mucosa NF-κB post inoculation pro-inflammatory cytokine pro-inflammatory gene produced provoke Regulation reservoir Respiratory disease respiratory syndrome coronavirus respiratory tract Simultaneous stimulated syndrome tissue damage tissues transcribed Transcription transcriptional regulation triggering Type type I Type III IFN understanding upregulation Vaccines viral infection virus virus clearance while
[DOI] 10.1371/journal.ppat.1009229 PMC 바로가기 [Article Type] Research Article

Immunological Aspects of SARS-CoV-2 Infection and the Putative Beneficial Role of Vitamin-D

Review

Published on 2021-05-162022-10-29
Journal: International Journal of Molecular Sciences [Category] COVID-19, SARS,

[키워드] ACE2 ACE2 expression activating Activation acute respiratory syndrome adaptive Adaptive immunity Alveolar Type II amplification angiotensin-converting enzyme 2 antibody Antigen antimicrobial peptide aspect attenuate autophagy B cells Bioavailability caused CD4 Cell cells circulating combating complex Concentration coronavirus Coronavirus disease 2019 Coronavirus-2 correlated COVID-19 criteria cytokine release Cytokine storm Cytokine storms defend Degradation determine dosage Effectiveness ENhance enzyme epithelial cell Evidence expression Future Health immune response Immunity incidence increase individuals with COVID-19 infect Inflammation inhibit inhibiting Innate immunity Interaction Local lysosomal macrophages mechanism meet Multiple nuclear observation Organ failure Particle Population pro-inflammatory cytokine progression promote RAS receptors renin–angiotensin–aldosterone system required responsible role SARS-CoV-2 SARS-CoV-2 viral particles secretion serum severe acute respiratory syndrome coronavirus 2 severity of COVID-19 shown Signaling Spike protein suppresse T cell T cells T helper tissue Toll-like receptor virus Vitamin D Vitamin D supplementation
[DOI] 10.3390/ijms22105251 PMC 바로가기 [Article Type] Review

Th17 Cells in Viral Infections—Friend or Foe?

Review

Published on 2021-05-112022-10-31
Journal: Cells [Category] COVID-19, SARS,

Impact of Inflammatory Immune Dysfunction in Psoriasis Patients at Risk for COVID-19

Article

Published on 2021-05-102022-10-28
Journal: Vaccines [Category] COVID-19,

Potential influence of Nagella sativa (Black cumin) in reinforcing immune system: A hope to decelerate the COVID-19 pandemic

면역 체계 강화에 Nagella sativa(블랙 커민)의 잠재적인 영향: COVID-19 전염병을 늦추기 위한 희망

Review

Published on 2021-05-012022-08-31
Journal: Phytomedicine : international journal of phytother [Category] SARS, 신약개발, 치료제,

[키워드] acute respiratory distress syndrome Anti-inflammatory antioxidant ARDS benefit black Black seed component components coronavirus COVID-19 COVID-19 pandemic COVID-19 patient Critical Cytokines disease severity Effect Evidence FDA approved Drugs human body immune immune modulation immune regulation immune response immune system immunomodulation indicated infected with COVID-19 intensive care intensive care unit modulation molecular molecular docking Molecular docking study Mortality Nagella sativa New coronavirus Nigella Sativa Nigellidine Obstructive pandemic pathophysiology Patient Potential pro-inflammatory cytokine pro-inflammatory cytokines provided respiratory respiratory disorders respiratory distress Respiratory distress syndrome severe cases severity Symptom the disease thymoquinone treat Treatment Vaccine α-hederin α-hederin.
[DOI] 10.1016/j.phymed.2020.153277 PMC 바로가기 [Article Type] Review