Clinical Characteristics of Coronavirus Disease (COVID-19) in Mexican Children and AdolescentsArticle Published on 2022-09-302022-11-15 Journal: Viruses [Category] SARS, 진단, [키워드] addition Adolescent analyzed Asthma children Children and adolescents clinical Clinical data Comorbidities Comorbidity coronavirus disease cough COVID-19 COVID-19 pandemic database determine diagnostic died Epidemiology evaluate Fever headache heterogeneous population hospital IgG IgG antibodies IgG antibody Immunosuppression incidence Ministry of Health Mortality obesity Patient patients pediatric polymerase chain Quantitative serology Symptom Symptoms Viral load was performed were used with COVID-19 [DOI] 10.3390/v14102162 PMC 바로가기
Obesity is associated with a higher Torque Teno viral load compared to leannessArticle Published on 2022-09-282022-11-15 Journal: Frontiers in Endocrinology [Category] 진단, [키워드] 95% CI acute respiratory syndrome Affect age Analysis association Bariatric surgery BMI confounder coronavirus coronavirus disease disease disease-associated Diseases fasting insulin Follow-up Host immune function immunocompetence in viral independent individual Infectious disease interleukin 6 IQR linear modeling marker median obese obesity outcome outcomes participant PCR positively correlated proportion quantified reflect rising risk risk factor risk stratification subjects torque torque teno virus viral immune response Viral load virus vitamin D levels weight loss [DOI] 10.3389/fendo.2022.962090 PMC 바로가기
Nasopharyngeal Wash with Normal Saline Decreases SARS-CoV-2 Viral Load: A Randomized Pilot Controlled TrialArticle Published on 2022-09-272022-11-16 Journal: Canadian Respiratory Journal [Category] SARS, 변종, [키워드] 24 hour acute respiratory syndrome administration Admission Antigen baseline control group Controlled Controlled trial coronavirus COVID-19 disease cycle threshold decrease demonstrated determine Epidemiology Fatality rate Follow-up healthcare Hospitalization hospitalized patient increase in microbial morbidity N gene nasal washe nasopharyngeal Nasopharyngeal swab nasopharyngeal viral load non-COVID-19 patient normal outcome Pathogenesis Patient performed Pneumonia previous study Randomized reduce reduction in resource Saline SARS-CoV-2 significant decrease significantly the SARS-CoV-2 Treatment two group two groups variant Viral load Viral transmission was collected was performed with COVID-19 [DOI] 10.1155/2022/8794127 PMC 바로가기
Theoretical Explanation for the Rarity of Antibody-Dependent Enhancement of Infection (ADE) in COVID-19Article Published on 2022-09-262022-11-15 Journal: International Journal of Molecular Sciences [Category] SARS, 진단, [키워드] ADE antibody Antibody-dependent enhancement cell cultures Complete computational modeling computational modeling. Concentration condition COVID-19 determine effective enhancement explain explanation Human Infection lack Macrophage mathematical Occurrence Probability proportion SARS-CoV SARS-CoV-2 SARS-COV-2 infection seroconversion time Spread the SARS-CoV-2 virus vaccination Viral load [DOI] 10.3390/ijms231911364 PMC 바로가기
Mouse models of COVID-19 recapitulate inflammatory pathways rather than gene expressionArticle Published on 2022-09-262022-11-16 Journal: PLoS Pathogens [Category] SARS, 유전자 메커니즘, [키워드] ACE2 Analysis approach bioinformatics Concordance COVID-19 debatable differentially expressed gene expressed expression Gene Expression hACE2 Human immune signature Immunity immunopathology inflammatory pathway K18-hACE2 lung damage Lungs mice mouse model orthologue overlap promoter SARS-CoV-2 single copy transcriptional profile transcriptional response Treatment Viral load virus wild-type [DOI] 10.1371/journal.ppat.1010867 PMC 바로가기
The Variation of Transcriptomic Perturbations is Associated with the Development and Progression of Various DiseasesArticle Published on 2022-09-262022-11-16 Journal: Disease Markers [Category] 유전자 메커니즘, [키워드] activities AIDS AIDS patient Algorithm analyzed applied association atrophic gastritis cardiovascular diseases caused cellular chronic obstructive clinical implication clinically controls COPD correlated correlation COVID-19 patient deficiency defined development digestive disease Disease diagnosis Disease progression Diseases Ejection fraction Endocrine diseases expiratory expression greater Health status heterogeneity ICU immune Infection intensive care investigated involved Kidney diseases liver diseases LVEF malaria mechanical ventilatory support negative correlation Neurological disorders non-ICU patients pathway patients Perturbation presymptomatic Prognosis pulmonary disease pulmonary tuberculosis Regulation respiratory diseases severity significantly syndrome the disease Therapies transcriptome datasets transcriptomic transcriptomic data treated upregulated upregulation Variation variety ventricular Viral load Volume [DOI] 10.1155/2022/2148627 PMC 바로가기
A Study on the Nature of SARS-CoV-2 Using the Shell Disorder Models: Reproducibility, Evolution, Spread, and AttenuationArticle Published on 2022-09-232022-11-16 Journal: Biomolecules [Category] SARS, 변종, [키워드] applied attenuation bat-CoV contagiousness coronavirus Coronaviruses correlated CoV COVID COVID-19 demonstrated disorder enzyme greater Hard immune system implication intrinsic Long COVID lung membrane protein Nature nucleocapsid protein nucleoprotein observation omicron pangolin Particle PID predicted PROTECT Replication Saliva SARS-CoV-2 shell supported tissues transmissions variant Viral load virion virulence virus [DOI] 10.3390/biom12101353 PMC 바로가기
Analysis of SARS-CoV-2 viral loads in stool samples and nasopharyngeal swabs from COVID-19 patients in the United Arab EmiratesArticle Published on 2022-09-222022-11-15 Journal: PLoS ONE [Category] SARS, 치료기술, [키워드] Analysis Antibiotics Blood clinical factors clinical information Coronavirus disease 2019 correlation cough COVID-19 COVID-19 patient COVID-19 patients cross-sectional demographic detectable Diagnosis diarrhea disorder Factor fecal Follow-up Gender highlight Hospitalization Infection investigated Isolation laboratory-confirmed male medical record Mild nasopharyngeal sample Nasopharyngeal swab nasopharyngeal swabs no correlation onset of symptom Participants Patient Pneumonia positive positive correlation positively correlated proportion questionnaire Regression respiratory sample rhesus SARS-CoV-2 viral load Stool stools Symptom tested the disease the patient United Arab Emirate United Arab Emirates Viral load Viral RNA virus was collected [DOI] 10.1371/journal.pone.0274961 PMC 바로가기
Digital PCR Applications in the SARS-CoV-2/COVID-19 Era: a Roadmap for Future OutbreaksArticle Published on 2022-09-212022-11-15 Journal: Clinical microbiology reviews [Category] SARS, 치료기술, [키워드] acute respiratory syndrome Affect affecting application caused Clinical diagnosis coronavirus coronavirus disease Course COVID-19 ddPCR Detection limit Diagnosis diagnosis and monitoring Digital digital PCR effective Factor false-negative Future global public health gold standard help infected patient Infectious disease knowledge magnitude Mutation outbreak Outbreaks pandemic PCR Precision quantification reproducibility RT-dPCR RT-qPCR SARS-CoV-2 selected sensitivity shown specificity subject tested Viral load [DOI] 10.1128/cmr.00168-21 PMC 바로가기
Suppression of SARS-CoV-2 Replication with Stabilized and Click-Chemistry Modified siRNAsArticle Published on 2022-09-192022-11-15 Journal: Angewandte Chemie (International ed. in English) [Category] SARS, 변종, 치료제, [키워드] Antiviral antiviral activity Antiviral compounds antiviral medication Apoptosis cell line Corona Corona pandemic cytotoxicity facilitate FIVE flexible Ligand lung magnitude mutations peptide peptide RNA conjugates receptor reduce RNA SARS-CoV-2 sequence siRNA suppression variants of concern variants of SARS-CoV-2 viral escape Viral load virus replication [DOI] 10.1002/anie.202204556 PMC 바로가기