cascade
[용어속성] Term
Carboxypeptidase B blocks ex vivo activation of the anaphylatoxin-neutrophil extracellular trap axis in neutrophils from COVID-19 patients
Research
[키워드] Activation
anaphylatoxin
antibodies
Bilirubin
block
carboxypeptidase
Carboxypeptidase B
cascade
CCK-8 assay
Cell
cell-free DNA
Coagulation
Coagulopathy
complement
component
contribute
COVID-19
COVID-19 patient
COVID-19 patients
CPB2
Critically ill patient
cytotoxicity
Degradation
degrade
demonstrated
Disease progression
endothelial
enzyme
evaluated
Ex vivo
Extracellular
help
homolog
Immunofluorescent staining
immunothrombosis
inactive
Intervention
lactate dehydrogenase
myeloperoxidase
NET
NETs
neutrophil
Neutrophil extracellular trap
pathological role
plasma
prevalent
Prevent
proinflammatory mediators
recruited
Regulation
Result
risk of death
thrombosis
thrombotic event
total bilirubin
Vascular
vascular endothelial cell
with COVID-19
[DOI] 10.1186/s13054-021-03482-z PMC 바로가기 [Article Type] Research
[DOI] 10.1186/s13054-021-03482-z PMC 바로가기 [Article Type] Research
Chromosome 3 cluster rs11385942 variant links complement activation with severe COVID-19
염색체 3 클러스터 rs11385942 변이체 링크는 심각한 COVID-19로 활성화를 보완합니다
Article
[키워드] ABO
ABO group
Activation
association
Blood Group
C5a
carried
carrier
carriers
cascade
chromosome
chromosome 3
circulating
Cluster
complement
Complement activation
Complement cascade
COVID-19
COVID-19 patients
COVID-19 severity
disease severity
European
GA variant.
gene cluster
genetic data
genetic susceptibility
Genetic variation
hospitalized patient
increased risk
mechanism
Patient
plasma
Plasma levels
remained
risk
risk allele
rs11385942 G>
SC5b-9
severe COVID-19
severity
terminal complement complex
upper airway
upper airways
variant
Variation
Viral
Viral load
with COVID-19
[DOI] 10.1016/j.jaut.2021.102595 PMC 바로가기 [Article Type] Article
[DOI] 10.1016/j.jaut.2021.102595 PMC 바로가기 [Article Type] Article
Severe COVID-19: A multifaceted viral vasculopathy syndrome
중증 코로나19: 다면적 바이러스성 혈관병증 증후군
Article
[키워드] activate
Activation
alveolar macrophage
Alveolar macrophages
Autopsies
basement membrane
Beta
blunting
Brain
capillary
cascade
caspase
caspase 3
cellular
characteristic
circulating
circulation
coagulation cascade
complement
Complement activation
COVID-19
COVID-19 infection
cytokine
Cytokine storm
Cytokines
death
docked
endocytosed
endothelial
Endothelial cell
endothelial cells
Endothelialitis
eosin
expression
fat
hematoxylin
Hematoxylin and eosin
Histopathology
host response
IL6
IL8
In situ
Infection
Infectious virus
macrophages
membrane
microangiopathy
pathophysiology
predict
prevalent
procoagulant
Protein
pseudovirion
pseudovirions
reduplication
Release
removal
response to therapies
resulting
SARS-CoV-2
septal
serious COVID-19
severe COVID-19
spike
Spike protein
subcutaneous fat
syndrome
the cytokine storm
therapy
TNF alpha
Viral
viral capsid
Viral load
Viral protein
Viral proteins
Viral RNA
viral spike protein
zone
[DOI] 10.1016/j.anndiagpath.2020.151645 PMC 바로가기 [Article Type] Article
[DOI] 10.1016/j.anndiagpath.2020.151645 PMC 바로가기 [Article Type] Article
Fighting the storm: could novel anti-TNFα and anti-IL-6 C. sativa cultivars tame cytokine storm in COVID-19?
폭풍과의 싸움: 새로운 항-TNFα 및 항-IL-6 C. sativa 품종이 COVID-19의 사이토카인 폭풍을 길들일 수 있습니까?
Research Paper
[키워드] acute respiratory distress
acute respiratory distress syndrome
addition
aging
anti-IL-6
anti-inflammatory effect
Anti-inflammatory effects
anti-inflammatory regimen
approach
ARDS
autoinflammatory disease
Cancer
cannabis
cascade
CCL2
cell line
complications
conditions
COVID-19
COVID-19 cytokine storm
COVID-19 disease
COVID-19 patient
COVID-19 patients
COX2
cytokine
Cytokine storm
Cytokines
death
Deleterious
disease
disease severity
down-regulation
downregulate
effective
Escalation
expression
fibroblast
fibrosis
Fighting
frailty
Gene Expression
had no
IL-6
include
induce
Inflammation
Inflammatory
Inflammatory cytokine
Initially
involved
lead
leads
lung
Lung fibrosis
medical cannabis
modulate
molecular
MOST
no effect
novel
Pathogenesis
pathway
Pathways
Prevent
pro-inflammatory cytokine
pro-inflammatory cytokines
proinflammatory cytokines
respiratory distress
responsible
rheumatological
SARS-CoV2
Seven
severe COVID-19 disease
syndrome
target
tested
therapeutic
These data
tissue
tissues
TNFα
TNFα
treat
treated
Treatment
[DOI] 10.18632/aging.202500 PMC 바로가기 [Article Type] Research Paper
[DOI] 10.18632/aging.202500 PMC 바로가기 [Article Type] Research Paper
Pleiotropy and epistasis within and between signaling pathways defines the genetic architecture of fungal virulence
신호 전달 경로 내 및 사이의 다면발광 및 상위성은 진균 독성의 유전적 구조를 정의합니다
Research Article
[키워드] Affect
amphotericin B
Analysis
antifungal drug resistance
approach
Author
avirulent
body temperature
CAMP
cascade
Cell
Cell signaling
cellular
cellular response
Cellular responses
characterization
Combination
complex
component
contribute
cross
Cryptococcal disease
Cryptococcus
cyclic AMP
disease
drug susceptibility
drugs
ENCODE
epistatic interaction
Europe
Extracellular
fungal
Genes
Genetic
genetic architecture
genetic difference
genetic differences
Genetic variation
glycerol
growth
highlight
human body
Infection
information
isolate
kinase
Lineage
locus
make up
mapping
microbial
modify
molecular
nucleotide
osmolarity
osmotic
oxidative
oxidative stress
oxidative stress resistance
pathogen
pathogenicity
Pathogens
pathway
phenotypic
phenotypic variation
physiological response
pleiotropic
polysaccharide capsule
progeny
promote
protein kinase
QTL
Quantitative
quantitative trait locus
regulate
regulator
sensitivity
Signal transduction
Signaling
signaling pathway
strain
Strains
Stress
temperate climates
thought
Tolerance
traits
underlie
Variation
virulence
virulent
[DOI] 10.1371/journal.pgen.1009313 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1371/journal.pgen.1009313 PMC 바로가기 [Article Type] Research Article
Epigenetic Evolution of ACE2 and IL-6 Genes: Non-Canonical Interferon-Stimulated Genes Correlate to COVID-19 Susceptibility in Vertebrates
Article
[키워드] ACE2
Analysis
angiotensin converting enzyme 2
angiotensin-converting enzyme 2
Biomarker
canonical
cascade
cause
Comorbidities
contagiousness
correlation
COVID-19
COVID-19 pathogenesis
COVID-19 susceptibility
Cytokine storm
Disease progression
Epigenetic
epigenetic regulation
Evolution
explain
Extensive
Factor
Gender
Host
IFN signaling
IL-6
IL6
Inflammatory
inflammatory stimuli
Interaction
interferon-stimulated gene
interferons
interferons (IFNs
ISGs
marker
Modification
novel coronavirus disease
performed
positive
predict
promoter
respond
response
shown
significantly higher
Spread
subgroups
subset
susceptibility
triggering
Vertebrate
virus
virus receptor
[DOI] 10.3390/genes12020154 PMC 바로가기 [Article Type] Article
[DOI] 10.3390/genes12020154 PMC 바로가기 [Article Type] Article
Case Report: B Lymphocyte Disorders Under COVID-19 Inflammatory Pressure
Oncology
[키워드] ACE-2
Acute lymphoblastic leukemia
acute respiratory syndrome
acute SARS-CoV-2 infection
Angiotensin converting enzyme-2
Autoimmune
autoimmune hemolytic anemia
B cell
B-cell
B-cell lineage malignancies
cascade
cells
Coronavirus-2
COVID-19
COVID-19 patient
disorder
disorders
event
expressed
Hematological malignancy
hemolytic anemia
Human
IL-6
infect
infected patients
Interaction
Lineage
lymphocyte
Lymphocytes
Multiple myeloma
new virus
overexpressed
pathologic
Patient
Peripheral blood
pressure
Reactivation
receptor
SARS-CoV-2
SARS-COV-2 infection
[DOI] 10.3389/fonc.2020.582901 PMC 바로가기 [Article Type] Oncology
[DOI] 10.3389/fonc.2020.582901 PMC 바로가기 [Article Type] Oncology
Elucidating the Interactions Between Heparin/Heparan Sulfate and SARS-CoV-2-Related Proteins—An Important Strategy for Developing Novel Therapeutics for the COVID-19 Pandemic
Molecular Biosciences
[키워드] cascade
caused
Cell
competing
coronavirus
Coronavirus infection
COVID-19
cytokine
death
defined
Developing
Diseases
drug
effective
Endothelial cell
expressed
heparan sulfate
heparin
high mortality
IL-6
Immune cell
Infection
Infectious disease
Inflammation
inflammatory reaction
Interaction
interactions
Invasion
involved
mechanism
modulation
novel
Protein
public health
recruitment
required
SARS-CoV-2
SARS-COV-2 infection
Spread
Strategy
subsequent
sulfate
therapeutic
Therapeutics
TNF-α
Treatment
Vaccines
viral entry
Viral protein
[DOI] 10.3389/fmolb.2020.628551 PMC 바로가기 [Article Type] Molecular Biosciences
[DOI] 10.3389/fmolb.2020.628551 PMC 바로가기 [Article Type] Molecular Biosciences
Enterovirus D68 molecular and cellular biology and pathogenesis
JBC Reviews
[키워드] accumulating
acute flaccid myelitis
Adaptive immunity
AFM
AFM, acute flaccid myelitis
antigens
cascade
CDC, US Centers for Disease Control and Prevention
cellular
change
changes in
children
contribute
COVID-19, Coronavirus disease 2019
eIF4, eukaryotic initiation factor 4
EMG, electromyography study
enterovirus
Enterovirus D68
Epidemiology
EV-A71, enterovirus A71
EV-D68, enterovirus D68
Genetic
GI, gastrointestinal
highlight
hnRNP, heterogenous nuclear ribonucleoprotein
host cell receptor
host cells
ICAM, intercellular adhesion molecule
include
Infection
Injury
Innate immunity
iPS, induced pluripotent stem cell
IRES, internal ribosome entry site
IVIG, intravenous immunoglobulin
MDA, melanoma differentiation–associated protein
metabolism
molecular
molecular feature
motor neuron
NCS, nerve conduction study
pathogen
Pathogenesis
pathogenic
receptor
Research
respiratory virus
responsible
RIG, retinoic acid–inducible gene
severe respiratory illness
similarity
strain
therapeutic approaches
TLR, Toll-like receptor
Toxicity
Viral RNA
virulence
virus replication
widespread
[DOI] 10.1016/j.jbc.2021.100317 PMC 바로가기 [Article Type] JBC Reviews
[DOI] 10.1016/j.jbc.2021.100317 PMC 바로가기 [Article Type] JBC Reviews