Liver transplant in a recently COVID-19 positive child with hepatoblastoma간모세포종을 가진 최근 COVID-19 양성 아동의 간 이식Case Reports Published on 2021-08-012022-09-12 Journal: Pediatric transplantation [Category] MERS, 진단, [키워드] antibody block clearance clinical Course COVID-19 Diagnosis discharge home disease Disease progression hepatoblastoma highlight IgG and IgM Immunosuppression initial liver liver transplant Liver transplantation male neutropenia NP swab Patient pediatric pediatric liver transplantation performed positive Prednisone product real-time RT-PCR regimen remained resolution of symptom risk SARS- CoV-2 SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 IgG antibody SARS-CoV-2 RT-PCR Test therapy viral infection with COVID-19 [DOI] 10.1111/petr.13880 PMC 바로가기 [Article Type] Case Reports
The Effects of Aβ 1-42 Binding to the SARS-CoV-2 Spike Protein S1 Subunit and Angiotensin-Converting Enzyme 2Article Published on 2021-07-302022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, SARS, [키워드] Aβ ACE2 acute respiratory syndrome Alzheimer’s disease Alzheimer’s disease angiotensin-converting enzyme 2 antibody binding Blood C-terminal clearance coronavirus Course COVID-19 Dementia domain Effect elevated Evidence Extracellular high affinity IL-6 Increasing intravenous mechanism prevented progression receptor reducing residue S1 subunit SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pseudovirus infection SARS-CoV-2 spike protein severe coronavirus disease severity spike the SARS-CoV-2 the spike protein trimer viral entry Viral protein [DOI] 10.3390/ijms22158226 PMC 바로가기 [Article Type] Article
Full-Length Recombinant hSP-D Binds and Inhibits SARS-CoV-2전장 재조합 HSP-D는 SARS-COV-2를 결합하고 억제한다Article Published on 2021-07-282022-09-10 Journal: Biomolecules [Category] Coronavirus, SARS, 변종, [키워드] ACE2 aggregation Anti-inflammatory Anti-viral bind binding binding assay Binding assays bronchoalveolar lavage sample bronchoalveolar lavage samples Caco-2 Caco-2 cell Caco-2 cells cells clearance Combined Concentration COVID-19 COVID-19 patient COVID-19 patients Critical driven by ELISA ELISAs epithelial evaluated facilitate followed by gel electrophoresis glycosylated healthy control healthy controls host cell host cells immune defense immune response in vitro induce inhibit initiate invading pathogen invading pathogens lung lung type II pneumocytes Lungs median member Pathogens Patient performed potential therapy Protein pulmonary recognize recombinant Replication reported Result SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 replication silver SP-D spike-protein staining Structure surfactant the SARS-CoV-2 type II pneumocytes variants Viral viral replication virus Virus Disease virus replication viruses were measured [DOI] 10.3390/biom11081114 PMC 바로가기 [Article Type] Article
Comparative analysis of two molecular tests for the detection of COVID-19 in Cameroon카메룬에서 Covid-19의 검출을위한 두 분자 테스트의 비교 분석Comparative Study Published on 2021-07-262022-09-01 Journal: The Pan African Medical Journal [Category] 진단, [키워드] 24 hour 24 hours 95% confidence interval age AmpliQuick® SARS-CoV-2 Attitude Bayesian Cameroon Chain Reaction city classic clearance Comorbidity Comparative analysis conducted COVID-19 COVID-19 testing cross-sectional Da An Gene RT-PCR determine Diagnosis diagnostic District Douala drastic reduction eight enrolled ethical clearance ethics committee help Laboratory latent class male Molecular biology molecular test MOST nasopharyngeal sample nationality over parameter participant patients PCR performed polymerase chain polymerase chain reaction Prevalence profession rapid response reduced resolved Result RT-PCR SARS-CoV-2 sensitivity significant level situation study period test results the median Transcription university was performed were recorded [DOI] 10.11604/pamj.2021.39.214.30718 PMC 바로가기 [Article Type] Comparative Study
Sodium Toxicity in the Nutritional Epidemiology and Nutritional Immunology of COVID-19Perspective Published on 2021-07-222022-10-30 Journal: Medicina [Category] COVID-19, SARS, [키워드] acute respiratory syndrome addition aggregate association Bell’s palsy cardiac arrhythmias cause clearance comorbid condition coronavirus COVID-19 diabetes dietary dietary intake dietary sodium intake disease Epidemiology etiology Evidence Factor Fever Government hepatic disease hypertension immunology impair Increased increases in inflammatory immune response Kidney disease mechanism morbidity and mortality mucosal immune mucosal immune system multiple sclerosis nasal nutritional epidemiology nutritional immunology obesity Outbreaks pathophysiology Pneumonia processed Pulmonary edema reduce reduced SARS-CoV-2 SARS-COV-2 infection Sepsis sodium sodium toxicity stroke sweating symptoms of COVID-19 syndrome Systemic sclerosis thrombosis Toxicity virion Virology [DOI] 10.3390/medicina57080739 PMC 바로가기 [Article Type] Perspective
Altered oral and gut microbiota and its association with SARS-CoV-2 viral load in COVID-19 patients during hospitalization입원 중 COVID-19 환자에서 변경된 구강 및 장내 미생물 및 SARS-CoV-2 바이러스 부하와의 연관성Article Published on 2021-07-222022-09-12 Journal: NPJ Biofilms and Microbiomes [Category] SARS, 바이오마커, 유전자 메커니즘, 진단, [키워드] 16S rRNA Alpha alteration Altered association Bacterial baseline Biomarkers calculated clearance clearance of SARS-CoV-2 clinical microbiology collected Community COVID-19 COVID-19 patient COVID-19 patients digestive tract dimension disease elevated examined Fecal sample fecal samples Gut gut microbiota healthy individual healthy individuals Hospitalization identify Immune homeostasis indicated intestinal flora investigated maintenance microbe microbes microbial Microbiome pathophysiology Patient rRNA SARS-COV-2 infection SARS-CoV-2 viral load Sequencing severity Sex susceptibility throat swab Treatment strategies treatment strategy Viral load vital role vital roles [DOI] 10.1038/s41522-021-00232-5 PMC 바로가기 [Article Type] Article
SARS-CoV-2 infection induces the dedifferentiation of multiciliated cells and impairs mucociliary clearanceSARS-CoV-2 감염은 다중 섬모 세포의 역분화를 유도하고 점액 섬모 청소를 손상시킵니다Article Published on 2021-07-162022-09-12 Journal: Nature Communications [Category] SARS, 진단, [키워드] airway airways Basal cell Bronchial epithelium cause Cell characterized cilia ciliary ciliated cells clearance consequence decrease dedifferentiation Defense defense mechanisms Disruption downregulation epithelial expression facilitate Foxj1 functional hamster identify impair in vivo induce interferon lung parenchyma master regulator mechanism mechanisms misorientation Motile cilia Mucociliary clearance occur parameter pathogenic reconstructed reduced respiratory tract resulting SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 replication severity of COVID-19 Spread spread to tight junctions to define transcription factor understanding viral particle [DOI] 10.1038/s41467-021-24521-x PMC 바로가기 [Article Type] Article
Clinical and virological course of patients with coronavirus disease 2019 in Jiangsu province, China: a retrospective, multi-center cohort studyResearch Published on 2021-07-142022-10-28 Journal: Virology Journal [Category] COVID-19, SARS, [키워드] 95% CI 95% confidence interval Analysis analyzed ARDS Characteristics China clearance clearance of SARS-CoV-2 clinical cohort study collected coronavirus disease Coronavirus disease 2019 Course COVID-19 COVID-19 patient Deceased duration of hospitalization epidemiological Factor hazard ratio hospital hospitalized patient ICU IMPROVE interferon interquartile range investigated Jiangsu Laboratory median multivariate Cox regression Patient promote recruited Respiratory failure Result retrospective SARS-CoV-2 SARS-CoV-2 clearance supplementary material treated Treatment Viral Virological with COVID-19 [DOI] 10.1186/s12985-021-01615-y PMC 바로가기 [Article Type] Research
A Single-Cell Atlas of Lymphocyte Adaptive Immune Repertoires and Transcriptomes Reveals Age-Related Differences in Convalescent COVID-19 Patients림프구 적응 면역 레퍼토리 및 전사체의 단일 세포 아틀라스는 회복기 COVID-19 환자의 연령 관련 차이를 보여줍니다Comparative Study Published on 2021-07-122022-09-11 Journal: Frontiers in Immunology [Category] SARS, 유전자 메커니즘, [키워드] Activation adaptive Adaptive immune response Adaptive immunity age Analysis antibody Atla B cell B cell receptor B cell receptors B cells B lymphocytes BCR CD4 CD8 Cell cell receptor clearance clone convalescent COVID-19 patient convalescent COVID-19 patients COVID-19 COVID-19 disease COVID-19 patient Critical cytotoxicity dependent on difference effector elderly patients elevated GNLY groups GzmA GZMH IgA immune Immunity implicated knowledge lymphocyte Lymphocytes marker outcome Patient patients plasma Plasma cell PRF1 receptor repertoire SARS-CoV-2 Sequencing single-cell T and B cells T and B lymphocytes T cell TCRs Transcriptome transcriptomes transition VDJ repertoire [DOI] 10.3389/fimmu.2021.701085 PMC 바로가기 [Article Type] Comparative Study
Viral dynamics of acute SARS-CoV-2 infection and applications to diagnostic and public health strategies급성 SARS-COV-2 감염의 바이러스 역학 및 진단 및 공중 보건 전략에 대한 적용Research Article Published on 2021-07-122022-09-10 Journal: PLoS Biology [Category] SARS, 진단, 치료기술, [키워드] 95% CI acute infections acute SARS-CoV-2 infection asymptomatic individual Asymptomatic individuals average certainty characterized clearance clinical care Concentration credible interval Cycle threshold value Decline diagnostic early stage early stages effective sensitivity followed by help identify IMPROVE individual Infection infectious initial Intervention mathematical mathematical model measure PCR testing peaked positive PCR test public health Quantitative remained reverse transcription PCR SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 viral stages Surveillance symptomatic individual symptomatic individuals Symptoms test turnaround time trajectory Viral viral clearance viral dynamics viral proliferation Viral RNA Viral RNA shedding [DOI] 10.1371/journal.pbio.3001333 PMC 바로가기 [Article Type] Research Article