The pH Dependence of Niclosamide Solubility, Dissolution, and Morphology: Motivation for Potentially Universal Mucin-Penetrating Nasal and Throat Sprays for COVID19, its Variants and other Viral Infections니클로사미드 용해도, 용해도 및 형태의 pH 의존성: COVID19, 그 변종 및 기타 바이러스 감염에 대한 잠재적으로 보편적인 점액 침투 비강 및 인후 스프레이에 대한 동기Article Published on 2022-01-012022-09-11 Journal: Pharmaceutical research [Category] 변종, 치료제, [키워드] Bioavailability cold chain Concentration concentrations contagious coronavirus COVID19 dependence dissolution distribution early treatment effective Efficacy epithelial cells Final help host cell host cell modulation Infection Local morphology motivation much lower nasal niclosamide niclosamide-solubility observé pandemic pH-dependent-dissolution polymorph precipitated Prevent Prophylactic reduce respiratory viral infections resulting sigma solubility Spectroscopy spray supernatant supersaturated solution Throat treat Universal universal nasal-throat-spray variants viral infection viral infections Viral load was used were measured [DOI] 10.1007/s11095-021-03112-x PMC 바로가기 [Article Type] Article
Computer-aided COVID-19 diagnosis and a comparison of deep learners using augmented CXRs컴퓨터 지원 COVID-19 진단 및 증강 CXR을 사용한 심층 학습기의 비교Article Published on 2022-01-012022-09-11 Journal: Journal of X-ray science and technology [Category] SARS, 치료기술, [키워드] Accuracy augmentation CAD caused characteristic chest X-rays Chest X-Rays (CXRs) classification CNN computer-aided diagnosis (CAD) contagious Convolution convolution neural network (CNN) coronavirus coronavirus disease Coronavirus disease 2019 COVID COVID-19 COVID-19 diagnosis CXR datasets death develop Diagnosis diagnosis of COVID-19 dry cough Early detection early diagnosis evaluated experiment False negative false-negative False-positive fatigue feature Fever Final help IMPROVE injection Long long short-term memory network (LSTM) manifested Medical imaging memory mortality rate network Neural positive rate producing Radiographic receiver operating characteristic Recurrent Recurrent Neural Network reduce respiratory tract infection ROC sensitivity Short-Term Memory specificity Symptom the disease TPR trained model variety [DOI] 10.3233/XST-211047 PMC 바로가기 [Article Type] Article
Rapid, multiplexed, and nucleic acid amplification-free detection of SARS-CoV-2 RNA using an electrochemical biosensor전기화학적 바이오센서를 사용하여 SARS-CoV-2 RNA의 빠르고 다중화된 핵산 증폭 없는 검출Article Published on 2022-01-012022-09-11 Journal: Biosensors & bioelectronics [Category] SARS, 치료기술, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 biosensor clinical sample contagious coronavirus COVID-19 COVID-19 outbreak detect diagnostic diagnostic test electrochemical biosensor evaluated Genes Health Health crisis hybridized mediator nucleic acid nucleic acid amplification ORF1ab gene platform positive probe qRT-PCR Rapid Respiratory disease S gene SARS-CoV-2 SARS-CoV-2 RNA severe acute respiratory syndrome Coronavirus severe respiratory disease Universal [DOI] 10.1016/j.bios.2021.113649 PMC 바로가기 [Article Type] Article
Initial Single-Center ST-Segment Elevation Myocardial Infarction Experience in New York Before and During the COVID-19 PandemicObservational Study Published on 2022-01-012022-10-05 Journal: Cardiovascular revascularization medicine : includ [Category] 임상, [키워드] activated Activation Acute myocardial infarction acute respiratory syndrome appear catheterization Characteristics conducted contagious coronavirus coronavirus disease COVID-19 COVID-19 pandemic COVID-19 patient demonstrated Diagnosis Elevation experience expired Healthcare system implication infection control island Laboratory Long LOS measure mimicking Mortality Myocardial infarction New York not differ offered pandemic Patient patients Percutaneous coronary intervention performed remained required resulting retrospective SARS-CoV-2 single center single-center study stability STEMI subset thrombolytics treated Variability virus [DOI] 10.1016/j.carrev.2021.01.026 PMC 바로가기 [Article Type] Observational Study
The virological impacts of SARS-CoV-2 D614G mutationSARS-CoV-2 D614G 돌연변이의 바이러스학적 영향Review Published on 2021-12-302022-09-11 Journal: Journal of Molecular Cell Biology [Category] SARS, 변종, 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 aspartic acid caused Characteristics circulating contagious coronavirus coronavirus disease coronavirus diseases COVID-19 D614G D614G mutation D614G variant defined effective epidemiological Evolution glycine Impact Infection Infectivity Intensive mechanism mechanisms Mutation over pathogenicity position presenting prevalent produced RNA virus SARS-CoV-2 SARS-CoV-2 D614G severe acute respiratory syndrome Coronavirus single-stranded positive-sense spike glycoprotein variant Virological virus virus mutation virus transmission [DOI] 10.1093/jmcb/mjab045 PMC 바로가기 [Article Type] Review
Systems Biology and Bioinformatics approach to Identify blood based signatures molecules and drug targets of patient with COVID-19Research article Published on 2021-12-302022-10-05 Journal: Informatics in Medicine Unlocked [Category] 바이오마커, [키워드] acute respiratory syndrome approach association AURKB bioinformatics Biology Biomarker Biomarker signatures Blood blood cell Blood cells Blood common gene BUB1B CCNB1 Cell connection contagious Coronavirus-2 COVID-19 dataset DEGs diagnose differentially expressed gene Differentially expressed genes disease DLGAP5 drug target effective Gene Expression Gene ontology HJURP hub protein Identified identify infected with SARS-CoV-2 Infection KIF11 Microarray molecular MONITOR mononuclear cell NCAPG New coronavirus Ontology pathophysiology pathway patient with COVID-19 patients with COVID-19 PBMCs PBMCs cell performed Peripheral blood prevalence of COVID-19 progression Research SARS-CoV-2 signaling pathways subjects System therapeutic intervention TOP2A TPX2 transcript transcriptomic Treatment TTK with COVID-19 [DOI] 10.1016/j.imu.2021.100840 [Article Type] Research article
COVID-19 Help-Seeking Behaviors: Application of the Theory of Planned BehaviorResearch Article Published on 2021-12-292022-10-28 Journal: Psychologica Belgica [Category] COVID-19, [키워드] affecting age application approval Attitude average Behavior close contact contagious COVID-19 COVID-19 knowledge cross-sectional early stage explain explained facilitate Factor female form Google help Help-seeking identify IMPROVE infected cases Intention knowledge knowledge score Measures MOST Multiple regression analysis novel coronavirus disease Pandemics participant Participants performed positive attitude predictors promote Regular seeking significantly Spread spread of COVID-19 theory Theory of Planned Behavior was related was used were used [DOI] 10.5334/pb.1034 PMC 바로가기 [Article Type] Research Article
Nitric Oxide: The Missing Factor in COVID-19 Severity? †산화질소: COVID-19 심각도에서 누락된 요소? †Hypothesis Published on 2021-12-232022-09-10 Journal: Medical Sciences [Category] SARS, 변종, [키워드] Comorbidities Comorbidity conditions contagious coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 symptom COVID-19 symptoms delta variant Depletion etiology Factor Hospitalization Hypothesis identify Infectious disease Intervention missing new strain Nitrate nitric oxide NO outcome Patient precursor respiratory respiratory tract SARS-CoV-2 Scientific community Sickness Spread Symptom transmission rates variant vascular disease widespread with COVID-19 [DOI] 10.3390/medsci10010003 PMC 바로가기 [Article Type] Hypothesis
Epidemiology of COVID-19: What changed in one year?Article Published on 2021-12-172022-10-29 Journal: Turkish Journal of Medical Sciences [Category] COVID-19, SARS, [키워드] case fatality rates changed contagious coronavirus country COVID-19 disease Effect epidemiological Epidemiology evaluate Evidence Final flu groups mortality risk pandemic risk severity the disease Transmission routes virus [DOI] 10.3906/sag-2110-153 PMC 바로가기 [Article Type] Article
Classification of COVID-19 and Pneumonia Using Deep Transfer Learning심층 전이 학습을 사용한 코로나19 및 폐렴 분류Research Article Published on 2021-12-162022-09-10 Journal: Journal of Healthcare Engineering [Category] MERS, SARS, 치료기술, [키워드] Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 affected age best caused children China classification CNN Contact contagious Convolutional neural network Coronavirus-2 COVID-19 CXR deep detect disease effective Features global pandemic globe Health Health Organization health problems immune system immune systems individual infected with COVID-19 learning life-threatening Pneumonia Precision problem referred to Research respiratory SARS-CoV-2 Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severity subject threshold transfer virus was used were used WHO World Health Organization [DOI] 10.1155/2021/3514821 PMC 바로가기 [Article Type] Research Article