Critical – Page 16 – Communicable Diseases Research

A critical overview of current progress for COVID-19: development of vaccines, antiviral drugs, and therapeutic antibodies

Article

Published on 2022-09-122022-11-15
Journal: Journal of Biomedical Science [Category] SARS, 변종, 신약개발, 치료제,

[키워드] abrogated acute respiratory syndrome addition Analysis antibodies antibody Antiviral antiviral drugs authorization BNT162b2 clinical benefits Clinical data clinical trial coronavirus COVID-19 Critical diagnostic distribution drug drugs Effect Effectiveness Efficacy effort Emergency global public health help Infection mRNA vaccines mRNA-1273 mutant strain Mutation Neutralizing antibodies neutralizing antibody neutralizing effect novel coronavirus disease omicron overcome pandemic presenting problems Regulatory SARS-CoV-2 SARS-CoV-2 strains SARS-CoV-2 variant Scientific community shown small molecule Small molecule antiviral drugs small molecule drugs Support the spike protein therapeutic Therapeutics Treatment utility Vaccine Vaccine development Vaccines variant variants widespread
[DOI] 10.1186/s12929-022-00852-9 PMC 바로가기

SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein

Article

Published on 2022-09-122022-11-15
Journal: PLoS Pathogens [Category] SARS, 치료제,

Noninvasive nasopharyngeal proteomics of COVID-19 patient identify abnormalities related to complement and coagulation cascade and mucosal immune system

Article

Published on 2022-09-122022-11-15
Journal: PLoS ONE [Category] SARS, 유전자 메커니즘, 치료기술, 치료제,

Conjugated Polymers-Based Biosensors for Virus Detection: Lessons from COVID-19

Article

Published on 2022-09-102022-11-15
Journal: Biosensors [Category] 치료기술,

The Rise and Fall of SARS-CoV-2 Variants and Ongoing Diversification of Omicron

Article

Published on 2022-09-102022-11-16
Journal: Viruses [Category] SARS, 변종, 치료기술,

Determinants of Neutralizing Antibody Response After SARS CoV-2 Vaccination in Patients With Myeloma

Article

Published on 2022-09-102022-11-15
Journal: Journal of clinical oncology : official journal of [Category] SARS, 변종, 진단, 치료기술,

[키워드] affected analyzed antibody B-cell malignancy BNT162b2 Booster vaccine Characteristics Critical Delta detect detectable determinant disease environmental exposure Factors greater hosts Immunocompromised implication increased risk induction initial lack Live virus Moderna MONITOR Mortality mRNA1273 much lower Multiple myeloma Myeloma NAb neutralization neutralize neutralizing antibody neutralizing capacity nucleocapsid Patient patients Pseudovirus neutralization assay quantified RBD receiving response SARS CoV-2 Seroconversion Serologic response significantly spike receptor-binding domain the vaccine Treatment vaccination Vaccine vaccine-induced antibody variant viral neutralization virus virus-neutralizing were measured
[DOI] 10.1200/JCO.21.02257 PMC 바로가기

Inflammatory Biomarkers Associated with In-Hospital Mortality in Critical COVID-19 Patients

Article

Published on 2022-09-092022-11-15
Journal: International Journal of Molecular Sciences [Category] 바이오마커,

[키워드] Analysis AST calculated Clinical course contribute COVID-19 COVID-19 pandemic creatinine Critical critical COVID-19 patients CRP cut-off demonstrated diagnosed with COVID-19 global healthcare groups healthcare identify IL-6 in-hospital mortality in-hospital mortality rate Inflammation Inflammatory biomarker inflammatory parameter INR Kaplan-Meier survival curve laboratory parameter marker Mortality non-survivor parameter Patient patients performed Predictive prognostic reducing retrospective risk stratification ROC significantly higher statistical analysis statistically significant statistically significant difference survival survivor thresholds urea WBC
[DOI] 10.3390/ijms231810423 PMC 바로가기

The complexity of examining laboratory-based biological markers associated with mortality in hospitalized patients during early phase of the COVID-19 pandemic: A systematic review and evidence map

Article

Published on 2022-09-092022-11-15
Journal: PLoS ONE [Category] 바이오마커, 진단,

Single-cell transcriptomics reveals common epithelial response patterns in human acute kidney injury

Article

Published on 2022-09-092022-11-15
Journal: Genome Medicine [Category] 유전자 메커니즘, 진단,

[키워드] Acute kidney injury adverse outcomes affected AKI Cell cell type changes in characterized Control COVID-19 criteria Critical Critical illness Critically ill patient diagnosed with COVID-19 disease disease-associated distal epithelial Gene Expression heterogeneity highlighting histology human kidney humans hypoxia Improving individual Injury inter-individual interferon response KDIGO kidney Kidney injury kidney tissue limbs mechanism molecular molecular responses occur oxidative stress performed Post-mortem provide proximal resource respiratory infections response reveal Sequencing single-cell sequencing Single-cell transcriptomics subtype Therapies Transcriptome transcriptomic transcriptomics
[DOI] 10.1186/s13073-022-01108-9 PMC 바로가기

Comparable bidirectional neutrophil immune dysregulation between Kawasaki disease and severe COVID-19

Article

Published on 2022-09-082022-11-15
Journal: Frontiers in Immunology [Category] SARS, 유전자 메커니즘, 진단,