Dynamics and Development of the COVID-19 Epidemic in the United States: A Compartmental Model Enhanced With Deep Learning TechniquesOriginal Paper Published on 2020-08-212022-10-30 Journal: Journal of Medical Internet Research [Category] COVID-19, MERS, [키워드] basic reproduction number Characteristics compartmental model Compartmental models confirmed case coronavirus disease COVID-19 COVID-19 epidemic cross current deep deep learning development Dynamics effective Effectiveness enhanced Epidemic Epidemiology estimation learning less methodology Model modeling objective parameter predict predicted reduced Result simulate suppressed technique the epidemic Transmission transmission parameter transmission parameters virus [DOI] 10.2196/21173 PMC 바로가기 [Article Type] Original Paper
Estimation of incubation period distribution of COVID-19 using disease onset forward time: A novel cross-sectional and forward follow-up studyResearch Article Published on 2020-08-142022-10-28 Journal: Science Advances [Category] COVID-19, MERS, [키워드] Accuracy adopted available data confidence interval COVID-19 cross-sectional disease onset distribution ENhance estimation follow-up study Incubation period individual median Patient presymptomatic Probability recall bia reducing Symptoms symptoms onset the disease Wuhan [DOI] 10.1126/sciadv.abc1202 PMC 바로가기 [Article Type] Research Article
Estimation of Renin-Angiotensin-Aldosterone-System (RAAS)-Inhibitor effect on COVID-19 outcome: A Meta-analysisResearch article Published on 2020-08-012022-10-05 Journal: The Journal of Infection [Category] SARS, 유전자 메커니즘, [키워드] ACEi ACEIs analyzed Angiotensin II receptor type 1 blockers Angiotensin II-converting enzyme inhibitors angiotensin-converting enzyme inhibitor ARB ARBs Arterial hypertension blocker cardiovascular disease Comorbidity contrary COVID-19 COVID-19 outbreak COVID-19 patient COVID-19 patients COVID-19 prognosis Critical Critical disease death diabetes effect size estimation explain higher risk Hospital admission hospitalized patient hypertension hypertensive patient Infection information inhibitor Intervention involved literature Meta-analysis outcomes Patient Prognosis protective effect RAAS RAAS inhibitors random effect receptor reduced risk Result risk of death suggested tested with COVID-19 [DOI] 10.1016/j.jinf.2020.05.052 [Article Type] Research article
Estimation of Coronavirus Disease Case-Fatality Risk in Real TimeExpedited Published on 2020-08-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, MERS, SARS, [키워드] 2019 novel coronavirus disease calculate calculated coronavirus coronavirus disease COVID-19 described early stage estimation parameter Previous studies respiratory infections risk SARS SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 the epidemic time trajectory viruses zoonoses [DOI] 10.3201/eid2608.201096 PMC 바로가기 [Article Type] Expedited
ACCORD: A Multicentre, Seamless, Phase 2 Adaptive Randomisation Platform Study to Assess the Efficacy and Safety of Multiple Candidate Agents for the Treatment of COVID-19 in Hospitalised Patients: A structured summary of a study protocol for a randomised controlled trialACCORD: 입원 환자의 COVID-19 치료를 위한 여러 후보 약제의 효능과 안전성을 평가하기 위한 다기관, 원활한, 2상 적응형 무작위화 플랫폼 연구: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2020-07-312022-08-13 Journal: Trials [Category] SARS, 임상, [키워드] 1:1 a BTK inhibitor Acalabrutinib adaptive added adjusted agent Amendment analyses Analysis Anti-viral approval Arm baseline bemcentinib Blinding block BTK inhibitor candidate Candidates cause caused changed clinical Clinical characteristics Clinical improvement clinically comparator complement COVID COVID-19 current Day discharge disease dissemination dropped Efficacy element Endpoint England estimation EudraCT evaluate Evidence evidence of experimental arm GRADE group help heparin hospital hospitalised include Inflammatory response inhibitor Ireland IRT Mask Master protocol Mild Mild disease monoclonal antibody Multiple nasal prongs National non-invasive ventilation number objective open open label Ordinal Scale outcome oxygen Oxygen therapy oxygen therapy) participant Patient performed Phase 2 phase II platform proceed protocol protocols provide randomisation randomised randomised controlled randomised controlled trial randomization recruited recruitment reduce Registered Regulatory reported Respiratory failure response response rate Safety Sample size SARS-COV-2 infection SARS-CoV-2 spike SARS-CoV-2 spike protein seamless selected severity shown SOC Spike protein Stage stage 2 stages Standard of care status stratified Study protocol sustained Task Force technology the spike protein the WHO therapy time treat Treatment treatment of COVID-19 Trial Trial registration Viral viral infection virus website with COVID-19 working zilucoplan [DOI] 10.1186/s13063-020-04584-9 PMC 바로가기 [Article Type] Letter
Estimation of COVID-19 spread curves integrating global data and borrowing informationResearch Article Published on 2020-07-292022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] adopted approved Bayesian country COVID-19 drug estimation food Health Hierarchical identify infected cases Infection information joint novel coronavirus disease outperform pandemic Predictive Prevent provide quantification risk factor severe disease Spread the disease trajectory treat virus [DOI] 10.1371/journal.pone.0236860 PMC 바로가기 [Article Type] Research Article
Estimation of SARS-CoV-2 mortality during the early stages of an epidemic: A modeling study in Hubei, China, and six regions in Europe전염병 초기 SARS-CoV-2 사망률 추정: 중국 후베이 및 유럽 6개 지역의 모델링 연구Research Article Published on 2020-07-282022-08-13 Journal: PLoS Medicine [Category] Biology and Life Sciences, COVID-19, SARS, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adjusted Affect affected age applied baseline biases calculated can be used Case–fatality ratio cause caused causes CFR changed China Clinical prognosis comparison Comparisons compartmental model coronavirus credible interval CrI date of onset death deaths disease early stage Epidemic estimate Estimated estimation Europe Factor Geographic difference Geographic differences geographic locations Germany Health Service healthcare heterogeneity highest IFR IMPROVE individual infected with SARS-CoV-2 Infection Infection transmission infection–fatality ratio investigated Italy less limitation lombardy lowest mathematical mathematical model measure MONITOR Mortality Older Outbreaks overall mortality Policy predict preferential ascertainment proportion public health ranged reduce Region reported required researcher respiratory right-censoring SARS-CoV-2 SARS-CoV-2 epidemic SARS-COV-2 infection sCFR SEIR severe acute respiratory syndrome Coronavirus Severe case severe cases severe symptoms Spain surveillance data susceptible-exposed-infected-removed Switzerland symptomatic case symptomatic case–fatality ratio the SARS-CoV-2 total size Transmission Transmission dynamics Transmission model [DOI] 10.1371/journal.pmed.1003189 PMC 바로가기 [Article Type] Research Article
On the True Number of COVID-19 Infections: Effect of Sensitivity, Specificity and Number of Tests on Prevalence Ratio EstimationArticle Published on 2020-07-242022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] arise COVID-19 COVID-19 pandemic Cross-sectional studies disease Effect estimation false positive and false negative probabilities finite number fraction increase individual molecular, serological and medical imaging diagnostics number number of infected number of infections parameter parameters policy-making and testing campaigns Positive test positive test result Precision Prevalence prevalence ratio Probability public health Ratio reducing SARS-CoV-2 second sensitivity Sensitivity and specificity shown specificity Test tested true negative true positive [DOI] 10.3390/ijerph17155328 PMC 바로가기 [Article Type] Article
Estimation of time-varying reproduction numbers underlying epidemiological processes: A new statistical tool for the COVID-19 pandemicResearch Article Published on 2020-07-212022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] classical Containment strategy coronavirus COVID-19 pandemic disease Effectiveness epidemiological estimation facilitate impacted inaccuracy pandemic parameter Poisson model random error reported Reproduction number Spread statistical the epidemic Transmission variant virus [DOI] 10.1371/journal.pone.0236464 PMC 바로가기 [Article Type] Research Article
Estimation of exponential growth rate and basic reproduction number of the coronavirus disease 2019 (COVID-19) in AfricaResearch Article Published on 2020-07-162022-10-29 Journal: Infectious Diseases of Poverty [Category] COVID-19, SARS, [키워드] 95% CI adopted African analyzed assumption average basic reproduction number Care China coronavirus disease country COVID-19 COVID-19 case COVID-19 epidemic COVID-19 infection COVID-19 pandemic cumulative curtail death described distribution effective estimate estimation examined gamma distribution growth Health initial instantaneous Intervention likelihood management measure Measures outbreak pandemic parameter per day Poisson quantified reached Reproduction number reproductive Result Spread Standard deviation Statistical modelling the disease the epidemic the WHO Transmissibility Travel Variation virus [DOI] 10.1186/s40249-020-00718-y PMC 바로가기 [Article Type] Research Article