Tracking SARS-CoV-2 Spike Protein Mutations in the United States (January 2020—March 2021) Using a Statistical Learning Strategy통계 학습 전략을 사용하여 미국에서 SARS-COV-2 스파이크 단백질 돌연변이 추적 (2020 년 1 월-2021 년 3 월)Article Published on 2021-12-212022-09-10 Journal: Viruses [Category] SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 alignment Analysis analyzed applied approach complementary coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 D1118H eight false discovery rate functional genomic Genomic surveillance GISAID highlight homology homology modelling identify identifying L452R learning MONITOR mutations proportion Protein protein sequence protein structure q-value reference strain residue respiratory SARS-CoV-2 sequence severe acute respiratory syndrome Coronavirus spatiotemporal spike Spike protein Spike protein sequence statistical statistical learning strain Strains Strategy Substitution supported Surveillance temporal dynamics the United State United States unsupervised learning variant variants variants of concern variants of interest Viral viral residue variant VOCs VOIs was performed [DOI] 10.3390/v14010009 PMC 바로가기 [Article Type] Article
Distinguishing gene flow between malaria parasite populations말라리아 기생충 집단 사이의 유전자 흐름을 구별합니다Research Article Published on 2021-12-202022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, 말라리아, [키워드] Analysis analyzed approach complementary conditions connectivity death descent disease disease control disperse distinguishing drug-resistant effort epidemiological evaluate gene flow Genetic genetic marker Genetic markers genomic Genomic surveillance geographic location geographic locations Guidance identity implementation implication include Infection information interpretability Interpretation Local malaria malaria control malaria parasite malaria parasites Metrics Migration Multiple National observation observations P. falciparum parasite Population populations public health question sampling sequence similar studies Spread strain Surveillance understanding whole genome sequence [DOI] 10.1371/journal.pgen.1009335 PMC 바로가기 [Article Type] Research Article
Geographical Landscape and Transmission Dynamics of SARS-CoV-2 Variants Across India: A Longitudinal PerspectiveGenetics Published on 2021-12-172022-10-31 Journal: Frontiers in Genetics [Category] COVID-19, [키워드] addition age Analysis Auspice B.1.1.7 lineage B.1.617 B.1.617.1 B.1.617.2 clade clades country COVID-19 dataset distribution Dynamics Evidence Evolution Gender genomes genomic Genomic surveillance GISAID Gujarat healthcare help include India indicated Integrative analysis knowledge landscape Lineage lineages longitudinal Longitudinal data Nextstrain pandemic Perspective predominant prevalent strain public health real time Regional replaced Repository reveal SARS-CoV-2 sequencing data Spread spread to Substitution Surveillance the SARS-CoV-2 Transmission Transmission dynamics variants of concern variants of interest virus VoC VOCs West [DOI] 10.3389/fgene.2021.753648 PMC 바로가기 [Article Type] Genetics
Identification of a novel SARS-CoV-2 P.1 sub-lineage in Brazil provides new insights about the mechanisms of emergence of variants of concernResearch Article Published on 2021-12-152022-10-28 Journal: Virus Evolution [Category] COVID-19, [키워드] accounted accumulated acute respiratory syndrome affected Analysis Brazil circulating complex interplay coronavirus described dissemination driving Epidemic Factor feature fixed fraction Gamma Genomic surveillance Hypothesis identification Lineage lineage P.1 mechanism Mutation natural selection new SARS-CoV-2 P.1 partial immunity Protein provide RBD RBD mutation reconstruction Region resolved SARS-CoV-2 SARS-COV-2 infection sequence strain subsequent Support the receptor-binding domain the S protein the Spike trajectory Transmission variant variant of concern Gamma variants of concern viral spread VoC VOCs [DOI] 10.1093/ve/veab091 PMC 바로가기 [Article Type] Research Article
Introduction and rapid dissemination of SARS-CoV-2 Gamma Variant of Concern in Venezuela베네수엘라에서 우려의 SARS-CoV-2 감마 변종 도입 및 급속 확산Article Published on 2021-12-012022-09-11 Journal: Infection, genetics and evolution : journal of mol [Category] SARS, 변종, 치료기술, [키워드] accumulated addition adopted antibody approach association Complete concern country COVID-19 dissemination dominant variant E484K E484K mutation East fragment of Frequency Gamma Genome sequencing genomic Genomic surveillance GISAID identify isolate less lineages MONITOR Mutation mutations neutralization New coronavirus predominant Protein Rapid Rapid screening Reinfection representing responsible robust SARS-CoV-2 sequence sequenced sequences shown Spike protein Surveillance the Spike Transmissibility variant variants variants of concern Venezuela viral genome Viral variants virus VoC VOCs WHO [DOI] 10.1016/j.meegid.2021.105147 PMC 바로가기 [Article Type] Article
SARS-CoV-2 introduction and lineage dynamics across three epidemic peaks in Southern Brazil: massive spread of P.1브라질 남부의 세 전염병 정점에 걸친 SARS-CoV-2 도입 및 계보 역학: P.1의 대규모 확산Article Published on 2021-12-012022-09-11 Journal: Infection, genetics and evolution : journal of mol [Category] SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis analyzed B.1 B.1.1 B.1.1.28 B.1.1.33 Brazil circulating Combination contributing to coordination coronavirus COVID-19 dataset Deletion deletions disease disease control dispersion Epidemic epidemic peak Epidemic peaks genetic diversity genomes genomic genomic diversity Genomic surveillance GISAID Health authority highlighting International Lineage lineages Mutation P.1 P.1 lineage P.2 phylogenetic inference Regional reported Rio Grande SARS-CoV-2 SARS-CoV-2 datasets SARS-CoV-2 genome SARS-CoV-2 genomes SARS-CoV-2 lineage sequence sequenced severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 spike mutation Spread Transmission viral dynamics [DOI] 10.1016/j.meegid.2021.105144 PMC 바로가기 [Article Type] Article
Emerging Mutations Potentially Related to SARS-CoV-2 Immune Escape: The Case of a Long-Term PatientArticle Published on 2021-11-182022-10-29 Journal: International Review of Cell and Molecular Biology [Category] COVID-19, [키워드] Apulia assigned average BNT162b2 clinical feature convalescent sera correlation COVID-19 COVID-19 pandemic COVID-19 patient genetic mutation genome mutations genomic Genomic surveillance highlight Infection Italy Lineage lineages long-term patient management mechanism Mutation P.1 Pangolin lineage persistence Pfizer/BioNTech positive Protein reduction SARS-CoV-2 SARS-CoV-2 isolate SARS-CoV-2 mutation seroneutralization assay Surveillance the Spike therapy Vaccines variant virus VoC WGS Whole genome sequencing whole-genome sequencing [DOI] 10.3390/life11111259 PMC 바로가기 [Article Type] Article
Finding the Middle Ground with the Clinical Laboratory’s Role in SARS-CoV-2 Genomic SurveillanceSARS-CoV-2 게놈 감시에서 임상 실험실의 역할로 중간 지점 찾기Article Published on 2021-11-182022-09-11 Journal: Journal of Clinical Microbiology [Category] SARS, 변종, 유전자 메커니즘, [키워드] Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 added Alpha approach assist characterized Clin clinical clinical sample clinical samples coronavirus Delta Delta variants dominant effort finding flexible generate genomic Genomic surveillance highlight identify journal Laboratory lineages medium Microbiology middle multiplex Mutation Next-generation sequencing NGS polymorphism public health Rapid replacement role SARS-CoV-2 sequence sequenced single-nucleotide single-nucleotide polymorphism SNP Surveillance the United State Threats United States variant variants [DOI] 10.1128/JCM.01816-21 PMC 바로가기 [Article Type] Article
Re-emergence of Gamma-like-II and emergence of Gamma-S:E661D SARS-CoV-2 lineages in the south of Brazil after the 2021 outbreak2021 년 발발 후 브라질 남쪽의 감마와 같은 II 및 감마 SARS-COV-2 계통의 재발Research Published on 2021-11-172022-09-10 Journal: Virology Journal [Category] MERS, SARS, 변종, 치료기술, [키워드] added addition age Analysis analyzed B.1.1.28 B.1.1.33 Brazil carried characterized circulating clade Clinical data correlation COVID-19 described dominance effort Evolution Frequency Gamma Gamma-like-II and new mutations Genome genomes genomic genomic sequence Genomic surveillance GISAID Lineage Mutation Older outbreak P.1 P.2 pandemic performed phylogenetic analyses Phylogenetic analyses of SARS-CoV-2 Phylogenetic tree predominant Protein provided ramification random Region responsible Result SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes SARS-CoV-2 lineage SARS-CoV-2 pandemic SARS-CoV-2 sequencing second wave sequence sequences supplementary material Surveillance the SARS-CoV-2 the SARS-CoV-2 genome thought variant variants VoC VOC Gamma was performed [DOI] 10.1186/s12985-021-01690-1 PMC 바로가기 [Article Type] Research
Evaluating the potential for respiratory metagenomics to improve treatment of secondary infection and detection of nosocomial transmission on expanded COVID-19 intensive care units확장된 COVID-19 중환자실에서 2차 감염 치료 및 병원 전파 감지를 개선하기 위한 호흡기 메타유전체학의 잠재력 평가Research Published on 2021-11-172022-09-10 Journal: Genome Medicine [Category] MERS, SARS, 유전자 메커니즘, 진단, 치료기술, 치료제, [키워드] 95% CI absence added Antibiotic resistance Antibiotics approach Aspergillus fumigatus Bacterial carried clinical clinical assessment COVID-19 COVID-19 pandemic Critical care Culture detect evaluated Evaluating expansion Genome genomic Genomic surveillance ICU ICUs IMPROVE increased risk Infection infection control infections initial intensive care unit intubated patient Laboratory MDR modify Nanopore nanopore sequencing nosocomial Nosocomial transmission outbreak pathogen pathogen detection Pathogens Patient pneumoniae positive presence or absence provide quantitative PCR reported Research respiratory respiratory sample Respiratory samples Result SARS-CoV-2 pandemic Secondary infection Sequencing sequencing data Seven supplementary material Surveillance translated Transmission Treatment [DOI] 10.1186/s13073-021-00991-y PMC 바로가기 [Article Type] Research