Smoking Is Correlated With the Prognosis of Coronavirus Disease 2019 (COVID-19) Patients: An Observational StudyPhysiology Published on 2021-03-032022-10-31 Journal: Frontiers in Physiology [Category] COVID-19, [키워드] 95% confidence interval ACE2 age analyzed association blood cell count Cerebrovascular disease China cigarette cigarette smoking collected COVID-19 COVID-19 patient Cox regression analysis creatinine Diseases enrolled female Gender hemoglobin higher risk incidence Inflammation Kaplan-Meier curve laboratory data Mortality non-survivor Patient patients patients with COVID-19 Prognosis proportion RANK Result risk factor SARS-CoV-2 significantly increased smoking statistical statistically significant survival survivor thought underlying diseases white with COVID-19 [DOI] 10.3389/fphys.2021.634842 PMC 바로가기 [Article Type] Physiology
ECMO in COVID-19—prolonged therapy needed? A retrospective analysis of outcome and prognostic factorsOriginal Papers Published on 2021-02-202022-10-28 Journal: Perfusion [Category] COVID-19, MERS, SARS, [키워드] acute respiratory distress ARDS Characteristics Clinical course Compliance COVID-19 COVID-19-associated ARDS ECMO ECMO therapy evaluated extracorporeal membrane oxygenation Factor Follow-up identify initiated Laboratory Mechanical non-survivor not affect occurred outcome outcomes parameters Patient patients Predictive Prognostic factor Prolonged required retrospective Retrospective analysis SARS-CoV-2 Seven single-center study SOFA score Support survived Survivors syndrome therapy Treatment Ventilation ventilatory Viral load Virological was performed [DOI] 10.1177/0267659121995997 PMC 바로가기 [Article Type] Original Papers
Implications of Laboratory Tests in Disease Grading and Death Risk Stratification of COVID-19: A Retrospective Study in Wuhan, ChinaMedicine Published on 2021-02-192022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] age analyses analyzed appear AUC Cerebrovascular disease characteristic clinical classification Clinical practice Clinical severity Combination COVID-19 Cox regression Critical critical condition death disease disease severity hospitalized patient IL-6 IL-6 level independent predictors independent risk factors indicated individual Laboratory laboratory data Laboratory test Logistic regression management Mild moderate Neutrophil-to-lymphocyte ratio non-severe group non-survivor outcome Patient Prediction model prognostic Prothrombin time provide risk risk factor risk stratification Risk-stratification ROC ROC analysis SARS-CoV-2 severe group severity Test urea nitrogen with COVID-19 Wuhan, China α-Hydroxybutyrate dehydrogenase [DOI] 10.3389/fmed.2021.629296 PMC 바로가기 [Article Type] Medicine
The effect of coagulation factors in 2019 novel coronavirus patients: A systematic review and meta-analysis2019년 신종 코로나바이러스 환자에서 응고인자의 효과: 체계적 고찰 및 메타분석Meta-Analysis Published on 2021-02-192022-09-11 Journal: Medicine [Category] MERS, 바이오마커, [키워드] 2019 novel coronavirus 95% CI aPTT ARDS Coagulation coagulation dysfunction coagulation factor coagulation function Coagulopathy contrary coronavirus disease Coronavirus disease 2019 correlation COVID-19 COVID-19 severity D-dimer D-dimer level D-dimer levels database degradation products dimer dysfunction elevated Evidence FIBRIN fibrinogen fibrinogen degradation products Future heterogeneity Hospitalization less marker Meta Meta-analysis MOOSE Mortality non-survivor observational studies observational study occurred Patient patients with COVID-19 Platelets Presence Prevalence progression PROSPERO Randomized controlled trial searched Severe case severe cases severe coronavirus disease severe COVID-19 Severe patient severe patients severity significantly SMD systematic review was increased was used with COVID-19 [DOI] 10.1097/MD.0000000000024537 PMC 바로가기 [Article Type] Meta-Analysis
Markers of endothelial and epithelial pulmonary injury in mechanically ventilated COVID-19 ICU patientsResearch Published on 2021-02-192022-11-01 Journal: Critical Care [Category] COVID-19, MERS, [키워드] acute respiratory distress syndrome alveolar Angiopoietin-2 ARDS AUROC bead-based multiplex immunoassay Biomarker Biomarkers can be used characterized classical Cohort COVID-19 Date detect E-selectin endothelial endothelial injury enrolled epithelial evaluate exhibited expression Ferrara Gas exchange ICAM-1 ICU ICU patient Inclusion Injury intensive care unit intercellular Intercellular adhesion molecule-1 mechanically ventilated mechanically ventilated patient Mortality Non-COVID-19 non-survivor Non-survivors not differ P-selectin Pathways Patient plasma plasma concentration predictor Primary outcome Prospective Study pulmonary endothelial pulmonary injury RAGE receptor Receptor for advanced glycation end-products reflect Respiratory mechanics Result secondary outcome selectin statistically survivor Survivors university variable vascular cell adhesion Vascular cell adhesion protein 1 VCAM-1 was performed with COVID-19 [DOI] 10.1186/s13054-021-03499-4 PMC 바로가기 [Article Type] Research
Interleukin-6 Is a Biomarker for the Development of Fatal Severe Acute Respiratory Syndrome Coronavirus 2 Pneumonia인터루킨-6은 치명적인 중증 급성 호흡기 증후군 코로나바이러스 2 폐렴의 발병을 위한 바이오마커입니다Clinical Trial Published on 2021-02-182022-08-13 Journal: Frontiers in Immunology [Category] MERS, 바이오마커, 임상, [키워드] “cytokine storm” acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age Alpha arterial blood Binary logistic regression Biomarker Blood C-reactive protein Cohort coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 CRP Cytokine storm death development Disease progression disease severity disease stages fatal pneumonia Hospital de Braga Hyper-inflammatory responses IIb and III IL-1 IL-6 IL-6 level IL-6 levels IL-8 indicated Inflammatory marker inflammatory markers Inflammatory mediators interleukin interleukin-1 Logistic regression Necrosis non-survivor outcome oxygen PaO partial pressure Partial pressure of oxygen Patient peripheral oxygen saturation positive correlation Predictive Predictive value Prognosis prognostic respiratory Respiratory failure response SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus significant negative correlation significantly Stage stages the disease Therapeutics TNFα Tumor tumor necrosis tumor necrosis factor tumor necrosis factor alpha [DOI] 10.3389/fimmu.2021.613422 PMC 바로가기 [Article Type] Clinical Trial
Do Blood Eosinophils Predict in-Hospital Mortality or Severity of Disease in SARS-CoV-2 Infection? A Retrospective Multicenter StudyArticle Published on 2021-02-082022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] acute respiratory syndrome Admission Characteristics circulating Cohort collected data conducted coronavirus COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients diagnosis of COVID-19 disease severity Eosinopenia eosinophil eosinophils Europe France hospital Hospitalized ICU implicated Infection Inflammatory initial intensive care leukocyte management marker moderate Mortality multicenter multicenter study multifunctional non-survivor not differ Pathogenesis patients predict Predictive presenting Prognostic value receiver Retrospective study ROC SARS-CoV-2 severe disease severity survivor the disease undetectable viral infections [DOI] 10.3390/microorganisms9020334 PMC 바로가기 [Article Type] Article
Effectiveness of mid-regional pro-adrenomedullin (MR-proADM) as prognostic marker in COVID-19 critically ill patients: An observational prospective studyCOVID-19 중환자에서 예후 마커로서 중부 프로아드레노메둘린(MR-proADM)의 효과: 관찰 전향 연구Observational Study Published on 2021-02-082022-08-13 Journal: PLoS ONE [Category] Biochemistry, MERS, 바이오마커, 임상, [키워드] 48 hour 48 hours 95% confidence interval adjusted Admission age AUC best Biomarkers C-reactive protein cardiovascular disease characterized COVID-19 COVID-19 adult patient COVID-19 ICU-patients COVID-19 patients COVID-19-ICU-patients Critically ill CRP CRP level CRP levels cut-off D-dimer diabetes Diabetes Mellitus dying patient dying patients effective Effectiveness enrolled explain Gender group higher mortality characterized patients ICU ICU admission increase in Laboratory Laboratory test Lactate lactate dehydrogenase LDH log-rank test logistic regression model lymphocyte Lymphocytes lymphocytopenia mechanism mid-regional pro-adrenomedullin Mortality MR-proADM MR-proADM measurement non-survivor NT-pro-BNP objective Odds ratio overall mortality Patient patients PCT predict Predictive procalcitonin Prognostic marker Prospective Study receiver-operating characteristics curves Referral responsible Result significantly Support survival curve Survival curves surviving and non-surviving patients tested university hospital were measured [DOI] 10.1371/journal.pone.0246771 PMC 바로가기 [Article Type] Observational Study
In-hospital mortality from severe COVID-19 in a tertiary care center in Mexico City; causes of death, risk factors and the impact of hospital saturationResearch Article Published on 2021-02-032022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, [키워드] 95% CI 95%CI acute respiratory distress acute respiratory syndrome Admission age ARDS Care cause contributed coronavirus country COVID-19 death death rate Diagnosis died enrolled Factor highest hospital hypertension ICU ICU care IMV In-hospital In-hospital death in-hospital mortality intensive care Invasive mechanical ventilation lack Latin America Male sex males Mexico City Mortality mortality rate non-survivor Non-survivors obese obesity oxygen saturation pandemic Patient patients hospitalized Pneumonia prospective cohort study receive remained risk factor Risk factors SARS-CoV-2 Septic shock severe COVID-19 Support Survivors syndrome the patient type 2 diabetes [DOI] 10.1371/journal.pone.0245772 PMC 바로가기 [Article Type] Research Article
Prognosis of COVID-19: Red Cell Distribution Width, Platelet Distribution Width, and C-Reactive ProteinInternal Medicine Published on 2021-02-022022-10-31 Journal: Cureus [Category] COVID-19, [키워드] Acute inflammation Admission affected age alteration association Autoimmune baseline C-reactive protein C-reactive protein (CRP category Cell Cell-mediated immunity circulation Clinical outcome college conducted Coronavirus disease 2019 COVID COVID-19 COVID-19 patient CRP Deceased Diagnosis disease disrupt distribution enrolled erythropoiesis family Government of India hematocrit hypoxia immature immune response increase increased mortality Infection Inflammation Lower malignancy management marker mechanical ventilation Ministry of Health moderate Mortality MPV Negative predictive value non-specific non-survivor outcome Patient patients Platelet platelet distribution width Predictive pro-inflammatory state Prognosis prognostic progression raised Red Red cell Red cell distribution width responsible Result Retrospective cross-sectional study sensitivity significantly study population survived survivor the disease Volume Welfare width [DOI] 10.7759/cureus.13078 PMC 바로가기 [Article Type] Internal Medicine