Serum hydroxybutyrate dehydrogenase and COVID-19 severity and mortality: a systematic review and meta-analysis with meta-regressionArticle Published on 2022-11-012022-11-15 Journal: Clinical and experimental medicine [Category] 바이오마커, [키워드] 95% CI Admission alteration Analysis Biomarker certainty of evidence Concentration conducted coronavirus disease COVID-19 COVID-19 patients COVID-19 severity disease severity effect size Egger estimates heterogeneity hospitalized COVID-19 patient hydroxybutyrate hydroxybutyrate dehydrogenase Inflammation Injury Liver damage magnitude marker Meta-analysis meta-regression moderate Mortality mortality. Myocardial myocardial injury non-specific non-survivor Patient performed renal renal function reported risk stratification searched Sepsis serum severity significantly significantly higher SMD standardized mean difference survival survivor systematic review tissue damage Web of Science [DOI] 10.1007/s10238-021-00777-x PMC 바로가기
The value of EEG attenuation in the prediction of outcome in COVID-19 patientsArticle Published on 2022-11-012022-11-16 Journal: Neurological Sciences [Category] SARS, 유전자 메커니즘, [키워드] biomarkers of inflammation Brain imaging brain involvement Cohort collected consecutive patients correlated correlation COVID-19 pandemic COVID-19 patient COVID-19 patients EEG EEG attenuation EEG background EEG suppression Encephalopathy epileptiform evaluated heterogeneous Hypoxemia identify in-hospital mortality lesion mechanism non-survivor Non-survivors Occurrence Organ failure outcome PaO patients performed Prevalence prevalent Prognosis recorded reduced reported SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2. significantly significantly lower suppressed [DOI] 10.1007/s10072-022-06354-8 PMC 바로가기
Association of Interleukin-17F Polymorphism and Mortality Predictors with the Risk of COVID-19Article Published on 2022-10-272022-11-15 Journal: International journal of clinical practice [Category] 변종, 진단, [키워드] age allele Analysis association AUC case-control study CD4 cells Characteristics control subject controls Coronavirus disease-19 COVID-19 COVID-19 infection COVID-19 mortality COVID-19 patient COVID-19 patients cutoff point D-dimer death determine enzyme-linked immunosorbent exhibiting expression Genotype genotyping healthy higher odd hypertension IL-17 immunological injuries in-hospital mortality independent predictor investigated Laboratory no significant difference non-survivor outcome participant polymorphism predictor proinflammatory risk of COVID-19 ROC Curve subset suggested survivor susceptibility T lymphocytes tested variant WBC White blood cell with COVID-19 [DOI] 10.1155/2022/4761631 PMC 바로가기
Limited value of neutrophil-to-lymphocyte ratio and serum creatinine as point-of-care biomarkers of disease severity and infection mortality in patients hospitalized with COVID-19Article Published on 2022-10-062022-11-15 Journal: PLoS ONE [Category] 바이오마커, [키워드] 95%CI Accuracy adjusted analyzed AOR association assumption Biomarker cohort study COVID-19 COVID-19 patient creatinine cut-off death disease severity elevated enrolled hospital hospitalized COVID-19 Infection IQR Limited males median age monitoring Mortality Neutrophil-to-lymphocyte ratio NLR non-survivor Odds ratio outcome Patient patients hospitalized point-of-care predict predictor Prognosis Prognostic marker progression Prospective receiver operating characteristics Sensitivity and specificity serum creatinine Severe case severity significantly significantly higher Still survivor the disease Treatment with COVID-19 [DOI] 10.1371/journal.pone.0275391 PMC 바로가기
Automated measurement of coagulation and fibrinolytic activation markers: Outcomes in coronavirus disease 2019 (COVID-19) patientsArticle Published on 2022-10-012022-11-15 Journal: International journal of laboratory hematology [Category] 바이오마커, [키워드] 95% CI accompanied Activation addition Admission automated Blood coagulation characterized chemiluminescent assays Coagulation collected complex coronavirus disease COVID-19 D-dimer Disease progression endothelial damage Endothelial dysfunction enzyme fibrinolysis fibrinolytic Haematology hospital hypoxaemia immunoassays independent independent risk factor inhibitor Logistic regression lung Mortality non-survivor Odds ratio oedema parameter Patient patients hospitalized performed retrospective significantly Survivors TAT thrombomodulin tissue variable Vascular endothelium Vascular endothelium. was performed with COVID-19 [DOI] 10.1111/ijlh.13855 PMC 바로가기
Prognostic value of von Willebrand factor and ADAMTS13 in patients with COVID-19: A systematic review and meta-analysisReview article Published on 2022-10-012022-10-05 Journal: Thrombosis research [Category] 바이오마커, 진단, [키워드] ADAMTS13 addition Admission analysis analyzed Antigen cause cleaving Clinical outcome Coagulation Coagulopathy Cochrane Library cofactor coronavirus disease COVID-19 COVID-19 patient Critical database death deficiency defined Effect endothelial injury estimate fixed FVIII ICU immunothrombosis increase indicated intensive care involved Ligand meta-analysis Meta-analysis metalloproteinase Mortality motif no significant difference non-ICU non-survivor outcome outcomes Patient patients with COVID-19 performed plasma poor prognosis Prognosis protease Quantitative random Result risk SARS-CoV-2 searched severe disease course Subgroup analysis survivor Survivors systematic review the Newcastle-Ottawa Scale variable von Willebrand factor vWF Web of Science [DOI] 10.1016/j.thromres.2022.08.017 [Article Type] Review article
Inflammatory Biomarkers Associated with In-Hospital Mortality in Critical COVID-19 PatientsArticle Published on 2022-09-092022-11-15 Journal: International Journal of Molecular Sciences [Category] 바이오마커, [키워드] Analysis AST calculated Clinical course contribute COVID-19 COVID-19 pandemic creatinine Critical critical COVID-19 patients CRP cut-off demonstrated diagnosed with COVID-19 global healthcare groups healthcare identify IL-6 in-hospital mortality in-hospital mortality rate Inflammation Inflammation. Inflammatory biomarker inflammatory parameter INR Kaplan-Meier survival curve laboratory parameter marker Mortality non-survivor parameter Patient patients performed Predictive prognostic reducing retrospective risk stratification ROC significantly higher statistical analysis statistically significant statistically significant difference survival survivor thresholds urea WBC [DOI] 10.3390/ijms231810423 PMC 바로가기
Effects of lymphocyte and neutrophil counts and their time courses on mortality in patients with postoperative pneumonia Research Published on 2022-08-262022-10-05 Journal: Scientific Reports [Category] 바이오마커, [키워드] Absolute lymphocyte count absolute neutrophil count ALC analyzed ANC change characteristic community-acquired pneumonia Course Diagnosis difference Effect evaluate evaluated feature highlight Hospitalization immunological increase in information lymphocyte lymphopenia Mortality neutrophil neutrophil count non-survivor Patient patients Pneumonia post-hoc analysis postoperative prognostic prognostic effect Prognostic factor Prolonged prospective observational study Research severe lymphopenia single-center survival survival rate survivor were assessed [DOI] 10.1038/s41598-022-18794-5 [Article Type] Research
Pulmonary pathophysiology development of COVID-19 assessed by serial Electrical Impedance Tomography in the MaastrICCht cohortObservational Study Published on 2022-08-252022-10-05 Journal: Scientific Reports [Category] SARS, 임상, 진단, [키워드] Admission alveolar analysed change changed changes in Cohort Compliance COVID-19 groups ICU impedance Intersection intubation knowledge Lung compliance lung mechanics measure mechanical ventilation mechanism non-survivor Non-survivors PaO parameter pathophysiologic pathophysiology Patient patients PEEP Positive end-expiratory pressure progression of disease prospective observational study pulmonary SARS-COV-2 infection SARS-CoV-2 patient survived survivor Ventilated [DOI] 10.1038/s41598-022-18843-z PMC 바로가기 [Article Type] Observational Study
The Associations of Iron Related Biomarkers with Risk, Clinical Severity and Mortality in SARS-CoV-2 Patients: A Meta-AnalysisSARS-CoV-2 환자의 위험, 임상 중증도 및 사망률과 철분 관련 바이오마커의 연관성: 메타 분석Review Published on 2022-08-192022-09-11 Journal: Nutrients [Category] SARS, 바이오마커, 치료기술, [키워드] 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition article Biomarker calculation caused clinical coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 progression deaths disease Diseases eligible evaluate Evidence ferritin ferritin level ferritin levels hemoglobin heterogeneity indicate Infection iron Iron metabolism iron. magnitude mean difference Meta-analysis metabolism Mortality non-survivor Non-survivors Occurrence opposite Patient peer-reviewed Previous studies previous study progression random effect respiratory risk SARS-CoV-2 searched serum severe acute respiratory syndrome Coronavirus severity significantly lower SMD Survivors the disease TIBC was used Web of Science with COVID-19 [DOI] 10.3390/nu14163406 PMC 바로가기 [Article Type] Review