Expression and purification of polioviral proteins in E. coli , and production of antisera as reagents for immunological assaysE. coli에서 폴리오바이러스 단백질의 발현 및 정제, 면역학적 분석을 위한 시약으로서의 항혈청 생산Article Published on 2016-12-012024-08-25 Journal: Protein Expression and Purification [Category] 폴리오, [키워드] Autoinduction immunoassays Poliovirus protein expression [DOI] 10.1016/j.pep.2016.08.014 PMC 바로가기 [Article Type] Article
Steps toward a globally available malaria vaccine: harnessing the potential of algae for future low cost vaccinesarticle Published on 2013-06-302024-09-01 Journal: Bioengineered [Category] 말라리아, [키워드] Algae Chlamydomonas reinhardtii chloroplast engineering malaria Pfs48/45 Plasmodium falciparum protein expression Transmission blocking vaccine [Article Type] article
Proteome Alterations in Primary Human Alveolar Macrophages in Response to Influenza A Virus InfectionArticle Published on 2012-07-042023-06-23 Journal: Journal of Proteome Research [Category] 신종인플루엔자, [키워드] IFN-α/β influenza A virus LC-MS/MS primary alveolar macrophage protein expression quantitative proteomics SILAC [DOI] 10.1021/pr3001332 PMC 바로가기 [Article Type] Article
Involvement of FOXO Transcription Factors, TRAIL-FasL/Fas, and Sirtuin Proteins Family in Canine Coronavirus Type II-Induced ApoptosisResearch Article Published on 2011-11-082022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, [키워드] activate Activation addition Analysis Blot canine cell death cell line cells coronavirus cytosol decrease demonstrated Effect expression extrinsic extrinsic apoptosis family found FoxO FOXO1 In vitro infection increase in induce Infection intrinsic apoptotic pathway investigated involved Involvement Ligand mitochondrial nuclear pathway post infection pro-apoptotic Protein protein expression Proteins regulate shown significantly SIRT1 SIRT3 SIRT4 sirtuin TRAIL transcription factor translocation Type virus infection [DOI] 10.1371/journal.pone.0027313 PMC 바로가기 [Article Type] Research Article
A randomized, double-blind, placebo-controlled study of an RNAi-based therapy directed against respiratory syncytial virusClinical Trial Published on 2010-05-112022-10-06 Journal: Proceedings of the National Academy of Sciences of [Category] 진단, [키워드] acquisition Administered Adult Adults Analysis antibody antiviral activity Antiviral effect assays clinical evidence concentrations decrease different double-blind Effectiveness enrolled exhibiting Factors healthy subject Human increase in independent Infected infected children Infection intranasal mechanism mRNA multiple logistic regression murine model nasal nasal washe nucleocapsid number of infected PCR Placebo placebo-controlled study placebo-controlled trial Proinflammatory cytokine proportion Protein protein expression Randomized recipient recipients representing respiratory syncytial virus RNA RSV RSV infection safety profile saline placebo significantly lower siRNA subjects tested therapeutic Therapeutic approach therapy treat uninfected unique viral culture was measured wild-type [DOI] 10.1073/pnas.0912186107 PMC 바로가기 [Article Type] Clinical Trial