clinically – Page 17 – Communicable Diseases Research

Early Th2 inflammation in the upper respiratory mucosa as a predictor of severe COVID-19 and modulation by early treatment with inhaled corticosteroids: a mechanistic analysis

중증 COVID-19의 예측인자로서 상부 호흡기 점막의 초기 Th2 염증 및 흡입 코르티코스테로이드 조기 치료에 의한 조절: 기계론적 분석

Clinical Trial

Published on 2022-06-012022-09-11
Journal: The Lancet. Respiratory Medicine [Category] COVID19(2023년), SARS, 바이오마커, 신약개발, 임상, 치료법, 치료제,

Identification, propagation and molecular characterization of SARS-CoV-2 delta variant isolated from Egyptian COVID-19 patients

이집트 COVID-19 환자에서 분리된 SARS-CoV-2 델타 변이체의 식별, 전파 및 분자 특성 분석

Article

Published on 2022-06-012022-09-11
Journal: Infection, genetics and evolution : journal of mol [Category] COVID19(2023년), SARS, 변종, 치료기술,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition applied B.1.617.2 beta-propiolactone causative agent cell line cell lines characterized China city clade clinically collected continuous monitoring coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient CPE Cytopathic effect Delta delta variant diagnosed with COVID-19 effective Effectiveness Efficacy Genetic genetic mutation Genetic variations genome sequence Genome sequences genomic sequence identification inactivated Isolation molecular Mutation rates nasopharyngeal swabs pandemic passage Patient PCR Prevalence Propagation provide qPCR reference strain Replication researcher RT-qPCR SARS-CoV-2 SARS-CoV-2 delta sequence severe acute respiratory syndrome Coronavirus Spread Swab the SARS-CoV-2 transmission rate Treatment protocol Vaccine variant variant of concern variants of concern Variation Vero E6 Vero E6 cell VERO E6 cells viral genome virus VoC was performed WGS whole genome Whole genome sequencing Wuhan-Hu-1
[DOI] 10.1016/j.meegid.2022.105278 PMC 바로가기 [Article Type] Article

Effectiveness of COVID-19 vaccination among people living with HIV during a COVID-19 outbreak

Short communication

Published on 2022-06-012022-10-05
Journal: Journal of microbiology, immunology, and infection [Category] 임상, 진단, 치료기술,

[키워드] clinically COVID-19 COVID-19 outbreak COVID-19 vaccination effective Effectiveness immunogenicity Intervention outbreak pandemic PLWH populations SARS-CoV-2 the vaccine vaccine effectiveness with HIV
[DOI] 10.1016/j.jmii.2022.04.006 [Article Type] Short communication

Serial Left and Right Ventricular Strain Analysis in Patients Recovered from COVID-19

Research article

Published on 2022-06-012022-10-05
Journal: Journal of the American Society of Echocardiograph [Category] 바이오마커, 진단,

Cytokine release syndrome-like serum responses after COVID-19 vaccination are frequent and clinically inapparent under cancer immunotherapy

Research

Published on 2022-06-012022-10-05
Journal: Nature cancer [Category] 임상, 진단, 치료기술, 치료법,

Ultrapotent and broad neutralization of SARS-CoV-2 variants by modular, tetravalent, bi-paratopic antibodies

모듈러, 4가, 2중 파라토프 항체에 의한 SARS-CoV-2 변이체의 초강력 광범위 중화

Article

Published on 2022-05-312022-09-11
Journal: Cell Reports [Category] COVID19(2023년), MERS, SARS, 변종, 진단,

[키워드] antibodies antibody approval bi-paratopic bind bispecific bivalent IgG breadth Characteristics chimeric clinically comparable Coverage COVID-19 CP: Immunology CP: Microbiology Emergency use exhibit format high potency IgGs immunology Microbiology mutational escape NAb NAbs neutralization neutralize neutralizes Neutralizing antibodies Passive immunotherapy platform pseudoviruses RBD robust S protein SARS-CoV-2 SARS-CoV-2 pseudoviruses SARS-CoV-2 spike protein SARS-CoV-2 variant Spike protein tetravalent the SARS-CoV-2 the spike protein therapeutic Treatment treatment of COVID-19 trimer variant variants variants of concern Viral viral variant virus virus variant. viruses
[DOI] 10.1016/j.celrep.2022.110905 PMC 바로가기 [Article Type] Article

SARS-CoV-2 Genome-Based Severity Predictions Correspond to Lower qPCR Values and Higher Viral Load

SARS-CoV-2 게놈 기반 심각도 예측은 더 낮은 qPCR 값 및 더 높은 바이러스 부하에 해당

Article

Published on 2022-05-312022-09-11
Journal: Global health, epidemiology and genomics [Category] COVID19(2023년), SARS, 변종,

Vaccination With Oral Polio Vaccine Reduces COVID-19 Incidence

경구용 폴리오 백신 접종이 COVID-19 발생률을 감소시킨다.

Randomized Controlled Trial

Published on 2022-05-302022-10-05
Journal: Frontiers in Immunology [Category] 임상, 폴리오,

[키워드] absence Acute respiratory infection Alter ARI Bacterial pathogens clinical clinically complement conducted Coronavirus vaccines Course COVID-19 COVID-19 cases develop diagnosed Effects emerging diseases Endpoint etiology evaluate the effect groups healthy volunteer heterogeneous Hypothesis immunization immunized in both group incidence incidence of COVID-19 induce infections innate immune responses Innate immunity Laboratory laboratory-confirmed Live attenuated vaccine non-specific non-specific protection observation OPV oral pandemic parallel-group participant pathogen Placebo protective effect Randomized reduced Region Respiratory illness SARS-CoV-2 Seasonal influenza shown significantly significantly lower single dose statistically significant study participant the vaccine threat Trial registration two group university Vaccine vaccine off-target effects.
[DOI] 10.3389/fimmu.2022.907341 PMC 바로가기 [Article Type] Randomized Controlled Trial

Implementation of the ERAS (Enhanced Recovery After Surgery) protocol for hysterectomy in the Piedmont Region with an audit&feedback; approach: Study protocol for a stepped wedge cluster randomized controlled trial. A study of the EASY-NET project

감사 및 피드백과 함께 Piedmont 지역의 자궁절제술을 위한 ERAS(수술 후 회복 강화) 프로토콜 구현 접근 방식: 계단형 쐐기형 클러스터 무작위 대조 시험을 위한 연구 프로토콜. EASY-NET 프로젝트 연구

Article

Published on 2022-05-272022-09-11
Journal: PLoS ONE [Category] 임상,

[키워드] activate adopted all the patients approach approved assigned changes in Clinical outcome Clinical studies clinical study clinically Cluster Committee Compliance complications Controlled trial COVID-19 pandemic detect effect size endpoints enhanced ERAS ethical committee expected four groups healthcare hospital Hospital stay Hospitalized Hysterectomy implementation Intervention involved LOS management multicenter outcome Patient peer-reviewed Piedmont positive Primary outcome promote protocol provide Randomized controlled trial randomized trial Randomly reduce reduction Region Result Sample size Satisfaction secondary Secondary outcomes selected Statistical power stratified Stress stress response Study protocol surgery surgical Surgical stress the patient Volume women
[DOI] 10.1371/journal.pone.0268655 PMC 바로가기 [Article Type] Article

Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice

다가 설계된 단백질은 우려되는 SARS-CoV-2 변이체를 중화하고 마우스의 감염에 대한 보호를 제공합니다

Article

Published on 2022-05-252022-09-11
Journal: Science Translational Medicine [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료제,

[키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Administered angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 antibody antigenic antigenic drift Antiviral apex autoimmune responses B.1.1.529 B.1.617.2 clinically coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Cryo-electron microscopy Delta Efficacy expression form greater Infection inhibitors of SARS-CoV-2 intranasally mice miniprotein monoclonal antibodies monoclonal antibody multivalent neutralize neutralized New omicron other variant pandemic pathogen Prophylactic Protein receptor Receptor binding domain receptor binding domains receptor binding site respiratory SARS-CoV-2 SARS-CoV-2 variant severe acute respiratory syndrome Coronavirus Spike protein tested the spike protein therapeutic therapeutic strategy Treatment treatment of COVID-19 trimeric spike TRIPOD variant Viral viral escape
[DOI] 10.1126/scitranslmed.abn1252 PMC 바로가기 [Article Type] Article