Cutoff – Page 17 – Communicable Diseases Research

Utility of d-dimer for diagnosis of deep vein thrombosis in coronavirus disease-19 infection

코로나바이러스 질병-19 감염에서 심부정맥 혈전증 진단을 위한 d-dimer의 유용성

Article

Published on 2021-01-012022-09-11
Journal: Journal of vascular surgery. Venous and lymphatic [Category] 바이오마커,

Significantly Decreased Mortality in a Large Cohort of Coronavirus Disease 2019 (COVID-19) Patients Transfused Early with Convalescent Plasma Containing High-Titer Anti-Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike Protein IgG

고역가 항중증급성호흡기증후군 코로나바이러스 2(SARS-CoV-2) 스파이크 단백질 IgG를 포함하는 회복기 혈장으로 조기에 수혈된 환자

Article

Published on 2021-01-012022-09-12
Journal: The American journal of pathology [Category] SARS, 진단,

Identification of biological correlates associated with respiratory failure in COVID-19

COVID-19에서 호흡 부전과 관련된 생물학적 상관 관계 식별

Research Article

Published on 2020-12-112022-09-10
Journal: BMC Medical Genomics [Category] MERS, SARS, 유전자 메커니즘,

[키워드] analyses Analysis analyzed bioinformatics biological processe Control coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patients curated Cutoff database determine Diseases downloaded epithelial explain false discovery rate Gene ontology Gene ontology analysis gene product Genes Genome-wide association study global public health GWAS identification implicated information input International Italy list list of gene loci mapped Ontology P -value p -values participant patients with COVID-19 polymorphism PPI protein-protein interaction recruited Respiratory failure Result risk SARS-CoV-2 single-nucleotide Single-nucleotide polymorphisms SNPs Spain unique genes was performed wound healing
[DOI] 10.1186/s12920-020-00839-1 PMC 바로가기 [Article Type] Research Article

Blood markers (lymphocyte percentages, neutrophils, CRP and ESR) can help in prioritizing rRT-PCR test for suspected COVID-19 patients in countries with limited health resources

혈액 표지자(림프구 백분율, 호중구, CRP 및 ESR)는 의료 자원이 제한된 국가에서 COVID-19 의심 환자에 대한 rRT-PCR 검사의 우선 순위를 정하는 데 도움이 될 수 있습니다.

Research

Published on 2020-12-102022-09-01
Journal: The Pan African Medical Journal [Category] MERS, 바이오마커, 진단,

[키워드] all the patients Analysis analyzed AUC best Blood blood count blood markers both sexes C-reactive protein CBC Chain Reaction characteristic China complete blood count confidence limit confidence limits coronavirus coronavirus disease Coronavirus disease 2019 country COVID-19 COVID-19 patient CRP Cutoff decrease erythrocyte sedimentation erythrocyte sedimentation rate ESR female Fisher gold gold standard group Health health resources help helping hospital individual Laboratory limit Liver function test liver function tests lymphocyte Lymphocytes male Mann-Whitney test marker median age Molecular diagnosis neutrophil Neutrophils outbreak Patient PCR test percentages physician plasma Plasma levels polymerase chain polymerase chain reaction positive RT-PCR qualitative variables quantitative variable quantitative variables Real-Time Reverse Transcription Polymerase Chain Reaction receiver receiver operating characteristic reduced renal function renal function tests resource Result reverse transcription reverse transcription polymerase chain reaction ROC rRT-PCR rRT-PCR test rRT-PCR tests RT-PCR sedimentation rate severe symptoms significance level significant increase Spread SPSS statistical analysis the patient variable was done was tested WBCs
[DOI] 10.11604/pamj.2020.37.331.25180 PMC 바로가기 [Article Type] Research

Global analysis of more than 50,000 SARS-CoV-2 genomes reveals epistasis between eight viral genes

530

Published on 2020-12-082022-10-29
Journal: Proceedings of the National Academy of Sciences of [Category] COVID-19, MERS, SARS,

Identifying the Zoonotic Origin of SARS-CoV-2 by Modeling the Binding Affinity between the Spike Receptor-Binding Domain and Host ACE2

스파이크 수용체 결합 도메인과 호스트 ACE2 간의 결합 친화도를 모델링하여 SARS-CoV-2의 인수공통 기원 확인

Article

Published on 2020-12-042022-09-11
Journal: Journal of Proteome Research [Category] SARS, 변종, 조류인플루엔자, 치료기술,

[키워드] ACE2 ACE2 protein ACE2 proteins ACE2 variant affinity amphibians Analysis approach binding binding affinity binding energy birds calculated candidate Candidates complex structure coronavirus correlated Critical Cutoff data sets determined by disease control domain Effectiveness EvoEF2 energy unit examined feasible fish highest Host host cells human infectious disease identify identifying Infection Infectious disease intermediate host intermediate hosts investigated Laboratory mammals modeling origin primates RBD reptiles Research risk of infection rodents SARS-CoV-2 spike receptor-binding domain susceptibility the binding affinity the Spike virus wild animals zoonotic origin
[DOI] 10.1021/acs.jproteome.0c00717 PMC 바로가기 [Article Type] Article

Development and External Validation of a Machine Learning Tool to Rule Out COVID-19 Among Adults in the Emergency Department Using Routine Blood Tests: A Large, Multicenter, Real-World Study

일상적인 혈액 검사를 사용하여 응급실의 성인에서 COVID-19를 배제하기 위한 기계 학습 도구의 개발 및 외부 검증: 대규모, 다기관, 실제 연구

Multicenter Study

Published on 2020-12-022022-09-12
Journal: Journal of Medical Internet Research [Category] MERS, SARS, 진단,

[키워드] 95% CI accelerate Accuracy artificial intelligence AUROC Chain Reaction characteristic Clinical data collected Conventional COVID 19 COVID-19 Cutoff data set decile demonstrated Department develop development Diagnosis diagnosis of COVID-19 electronic medical records Emergency emergency department excluded External external validation Frame hospital hospitals Laboratory laboratory data Laboratory results Laboratory test machine machine learning male median age Model multicenter negative control negative controls Negative predictive value NPV objective outcome pandemic Patient patients PCR PCR-based testing PCR-confirmed polymerase chain polymerase chain reaction predicted Predictive value Prevalence receiver operating characteristic Result reverse transcription reverse transcription polymerase chain reaction risk routine routine blood test routine blood tests RT-PCR rule SARS-CoV-2 SARS-CoV-2 virus score cutoff selective sensitivity specificity Testing Time frame validation
[DOI] 10.2196/24048 PMC 바로가기 [Article Type] Multicenter Study

Prevalence of phenotypes of acute respiratory distress syndrome in critically ill patients with COVID-19: a prospective observational study

Observational Study

Published on 2020-12-012022-10-04
Journal: The Lancet. Respiratory Medicine [Category] Coronavirus, Fulltext, MERS, 임상,

[키워드] acute respiratory distress analysed ARDS baseline calculate cause Classifier Cohort collected Concentration COVID-19 COVID-19-associated ARDS Critically ill patient Cutoff demographic described died eight Exploratory analysis FIVE Health Hyperinflammatory identify IL-6 inflammatory pathway inspired air intensive care units interleukin-6 IQR laboratory data median Mortality multicentre multiorgan failure Necrosis Older oxygen PaO Patient patients patients with ARDS phenotype Phenotypes point-of-care Prevalence Probability proportion prospective observational study randomised controlled trial receptor recruited severity significantly lower Survivors syndrome systemic inflammation TNFR1 unlikely upregulation was used
[DOI] 10.1016/S2213-2600(20)30366-0 PMC 바로가기 [Article Type] Observational Study

Chest CT in COVID-19 at the ED: Validation of the COVID-19 Reporting and Data System (CO-RADS) and CT Severity Score A Prospective, Multicenter, Observational Study

응급실에서 COVID-19의 흉부 CT: COVID-19 보고 및 데이터 시스템(CO-RADS) 및 CT 심각도 점수 A 전향적, 다기관, 관찰 연구

Observational Study

Published on 2020-11-302022-09-12
Journal: Chest [Category] SARS, 임상, 진단,

[키워드] 30-Day mortality acute respiratory syndrome adjusted analyzed association AUC AUC, area under the curve calculated Chest CT CO-RADS, COVID-19 Reporting and Data System conducted coronavirus coronavirus disease correlation coefficient COVID-19 COVID-19, Coronavirus disease 2019 CT ctss CTSS, CT severity score CUSUM, cumulative sum control chart Cutoff Diagnosis diagnostic Diagnostic accuracy diagnostic workup emergency medicine evaluate Hospital admission ICU admission increase in introduced management MDT, multidisciplinary team of experts measure Netherland Netherlands NVvR, Radiological Society of the Netherlands Patient PCR PCR, polymerase chain reaction Pneumonia presenting Prognosis Prospective reported Reporting Result SARS-CoV-2 score sensitivity severity Society specificity Support System this system thought validation was performed WHO, World Health Organization
[DOI] 10.1016/j.chest.2020.11.026 PMC 바로가기 [Article Type] Observational Study

Risk Stratification of COVID-19 Patients Using Ambulatory Oxygen Saturation in the Emergency Department

Endemic Infections

Published on 2020-11-242022-10-28
Journal: Western Journal of Emergency Medicine [Category] COVID-19, SARS,

[키워드] Admission Admitted Patient ambulatory Analysis association average clinically clinician coronavirus disease cough COVID-19 COVID-19 pandemic Cutoff defined Department deteriorate determine discharge discharged patient discharged patients Emergency evaluated Fever help Hospitalization identify Illness severity initial less Logistic regression mechanical ventilation New York New York City outcome outcomes oxygen Oxygen requirement oxygen saturation Patient patients performed predicted required Result resulting retrospective saturation Shortness of breath significantly lower subsequent suggested university vital signs
[DOI] 10.5811/westjem.2020.8.48701 PMC 바로가기 [Article Type] Endemic Infections