Humoral immune response following SARS-CoV-2 mRNA vaccination concomitant to anti-CD20 therapy in multiple sclerosis다발성 경화증에서 항 CD20 요법과 함께 SARS-CoV-2 mRNA 백신 접종 후 체액 면역 반응Article Published on 2021-11-012022-09-11 Journal: Multiple sclerosis and related disorders [Category] MERS, SARS, 진단, 치료기술, [키워드] Abbott Abbott Laboratories anti-CD20 anti-CD20 therapy B-cell binding domain BNT162b2 BNT162b2 mRNA Booster vaccine CD20 clinical clinical trials COVID-19 COVID-19 vaccine depleting determine domain Efficacy exposure to FIVE Future humoral IgG immune protection immune response immunogenicity Immunoglobulin Immunoglobulin G implication investigated monoclonal antibody mounted mRNA vaccination multiple sclerosis Ocrelizumab Patient patients patients treated positive Predictive Predictive value receiving SARS-CoV-2 SARS-CoV-2 IgG II Quant assay SARS-CoV-2 spike SARS-CoV-2 spike receptor-binding domain SARS-CoV-2 vaccine second dose second dose of vaccine seronegative seropositive the SARS-CoV-2 therapy treated patient Treatment vaccination Vaccine vaccine efficacy were measured [DOI] 10.1016/j.msard.2021.103251 PMC 바로가기 [Article Type] Article
Pre-existing T cell-mediated cross-reactivity to SARS-CoV-2 cannot solely be explained by prior exposure to endemic human coronavirusesSARS-CoV-2에 대한 기존 T 세포 매개 교차 반응성은 고유한 인간 코로나바이러스에 대한 사전 노출만으로는 설명할 수 없습니다Article Published on 2021-11-012022-09-12 Journal: Infection, genetics and evolution : journal of mol [Category] MERS, SARS, 진단, [키워드] Antigen can not common cold core genes Coronaviridae Coronaviridae family coronavirus cross-reactive cross-reactivity dataset endemic human coronavirus epitope Epitopes expected explain explained exposure to family Coronaviridae Genetic had no HCoVs Highlights homology individual Pearson peptide peptides Phylogenetic Phylogeny pre-existing immunity profiles proportion Protein proteome random reconstructed reported SARS-CoV-2 sequence sequence homology similarity suggested T-cell T-cell epitope T-cell-mediated immunity tested the Coronaviridae [DOI] 10.1016/j.meegid.2021.105075 PMC 바로가기 [Article Type] Article
Mortality and critical care unit admission associated with the SARS-CoV-2 lineage B.1.1.7 in England: an observational cohort study영국의 SARS-CoV-2 계통 B.1.1.7과 관련된 사망률 및 중환자실 입원: 관찰 코호트 연구Observational Study Published on 2021-11-012022-09-10 Journal: The Lancet. Infectious Diseases [Category] MERS, SARS, 변종, 임상, [키워드] 28-day mortality 95% CI adjusted adjusted hazard ratio adjusted hazard ratios Admission age association Asthma Audit B.1.1.7 body-mass body-mass index cardiovascular disease case mix CCU chronic obstructive chronic obstructive pulmonary disease Clinical outcome clinical outcomes Cohort Community Comorbidities Comorbidity COVID-19 test COVID-19 testing Critical care Critically ill dependency Deprivation diabetes diagnostic died division Ethnicity exposure to finding funding geographical region groups hazard ratios hospital HRs hypertension immunocompromised condition increased risk independent independent of Infection infection with COVID-19 information Lineage Lineage B.1.1.7 measure Medical Science metastatic disease molecular Mortality National Observational cohort study obstructive pulmonary disease on type on types organ support overall mortality Oxford Patient patients with SARS-CoV-2 positive positive sample primary care Public Health England pulmonary disease QResearch receiving reported respiratory Respiratory disease risk S-gene SARS-CoV-2 SARS-COV-2 infection Sex smoking status Sociodemographic factor the SARS-CoV-2 two groups University of Oxford variant variant of SARS-CoV-2 virus strain Wellcome Trust [DOI] 10.1016/S1473-3099(21)00318-2 PMC 바로가기 [Article Type] Observational Study
High class filtering facepiece (FFP) are fundamental and effective in protection of emergency health care workers: an observational cohort study in a German community고급 필터링 안면부(FFP)는 응급 의료 종사자를 보호하는 데 기본적이고 효과적입니다. 독일 커뮤니티의 관찰 코호트 연구Observational Study Published on 2021-10-302022-09-10 Journal: Scandinavian Journal of Trauma, Resuscitation and [Category] MERS, SARS, 변종, 임상, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus addition airway Analysis analyzed aspect belief Care Chain Reaction Cohort Community condition Contact contagious Coronavirus disease 2019 Coronavirus-2 COVID-19 COVID-19 infections disease effective Effectiveness Efficiency emergency medical service Emergency medical services exposure to FFP2 Filtering facepiece flu Health Hospital staff immunoassay incidence involved lowest Masks medical service medical staff N95 NPC Observational cohort study pandemic coronavirus participant Patient Patient care PCR Personal protection equipment physical polymerase chain polymerase chain reaction positive positive PCR positive SARS-CoV-2 result Prevent quantity respiratory Result SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 positive patient SARS-CoV-2 positive patients self-assessment Seroprevalence severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 significantly higher Symptom three group three groups Vaccines Viral viral variant virus was performed [DOI] 10.1186/s13049-021-00969-0 PMC 바로가기 [Article Type] Observational Study
Community‐based differentiated service delivery models incorporating multi‐month dispensing of antiretroviral treatment for newly stable people living with HIV receiving single annual clinical visits: a pooled analysis of two cluster‐randomized trials in southern Africa매년 단일 임상 방문을 받는 HIV에 감염된 새로 안정된 사람들을 위한 항레트로바이러스 치료의 수개월 분배를 통합하는 지역 사회 기반의 차별화된 서비스 제공 모델: 남아프리카의 2건의 클러스터 무작위 시험에 대한 통합 분석Meta-Analysis Published on 2021-10-282022-09-10 Journal: Journal of the International AIDS Society [Category] MERS, SARS, 임상, 치료제, [키워드] 95% CI acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adjusted Analysis antiretroviral antiretroviral treatment ARMS ART CAG Care Clinic visits clinical cluster‐randomized trial Clustering Community conducted coronavirus country COVID‐19 decrease differentiated service delivery Effectiveness enrolled enrolment Evidence exposure to Frequency group Health healthcare healthcare facility HIV treatment incidence rate include Intervention intervention arms limit margin multi‐month dispensing not increased operational research participant Primary outcome provided rate ratio receiving regression analysis respiratory Result retained retention risk risk difference risk ratio secondary outcome Secondary outcomes severe acute respiratory syndrome Coronavirus SOC Treatment Trial Viral visit frequency with HIV Zimbabwe [DOI] 10.1002/jia2.25819 PMC 바로가기 [Article Type] Meta-Analysis
High Seroprevalence of SARS-CoV-2 (COVID-19)-Specific Antibodies among Healthcare Workers: A Cross-Sectional Study in Guilan, Iran의료 종사자 사이에 SARS-CoV-2(COVID-19) 특이 항체의 높은 혈청 유병률: 이란 구이란의 횡단면 연구Research Article Published on 2021-10-222022-09-10 Journal: Journal of Environmental and Public Health [Category] MERS, SARS, 진단, 치료기술, [키워드] 95% CI age anti‐SARS‐CoV‐2 IgG anti‐SARS‐CoV‐2 IgM antibody Antibody test association Awareness blood sample Blood samples collected company conducted COVID-19 cross-sectional cross-sectional study ELISA enzyme enzyme-linked immunosorbent assay evaluate exposure to Fever healthcare healthcare worker Healthcare workers IgG antibodies IgG antibody IgM/IgG indicated Iran lack lack of awareness Odds ratio pandemic participant Participants physician positive quantitation Rasht Result SARS-CoV-2 Seroprevalence significantly significantly more subject Symptom Tehran was used [DOI] 10.1155/2021/9081491 PMC 바로가기 [Article Type] Research Article
A retrospective survey study of paramedic students’ exposure to SARS-CoV-2, participation in the COVID-19 pandemic response, and health-related quality of life구급대학생의 SARS-CoV-2 노출, COVID-19 전염병 대응 참여 및 건강 관련 삶의 질에 대한 후향적 조사 연구Original Research Published on 2021-10-182022-09-10 Journal: Scandinavian Journal of Trauma, Resuscitation and [Category] MERS, SARS, 치료기술, [키워드] aerosol-generating procedure aerosol-generating procedures Ambulances analyzed Anxiety clinicians and researchers Complete COVID-19 COVID-19 pandemic COVID-19-related symptom COVID-19-related symptoms Descriptive statistics Emergency medical services Emergency medical technicians epicenter equipment evaluate exposure to First wave FIVE General population Health Health crisis Health personnel healthcare healthcare work healthcare worker hospital independent International involved life Linear regression analysis National nine Norway pandemic Pandemics paramedic participated positive PPE Quality of life remained reported response Result retrospective SARS-CoV-2 SARS-CoV-2 virus scored Seven significantly higher student students T-tests tested the SARS-CoV-2 virus university utilization variety virus [DOI] 10.1186/s13049-021-00967-2 PMC 바로가기 [Article Type] Original Research
Risk factors for breakthrough SARS-CoV-2 infection in vaccinated healthcare workersResearch Article Published on 2021-10-152022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] age Breakthrough infection Contact Control Corporation Course Cox regression analysis determine excluded exposure to Factor group HCW Healthcare system healthcare worker Infection Midwifery National negative test Patient positive Positive test predicted Presence professional Result risk factor SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RT-PCR SARS-CoV-2 testing Sex Symptom vaccination vaccine dose [DOI] 10.1371/journal.pone.0258820 PMC 바로가기 [Article Type] Research Article
Clinical and epidemiological characteristics of patients seeking COVID-19 testing in a private centre in Malaysia: Is there a role for private healthcare in battling the outbreak?말레이시아 민간 센터에서 COVID-19 검사를 원하는 환자의 임상 및 역학적 특성: 발병과 싸우는 데 민간 의료의 역할이 있습니까?Research Article Published on 2021-10-142022-09-12 Journal: PLoS ONE [Category] MERS, 진단, [키워드] 95% CI accounted Analysis Asymptomatic average baseline characteristics characteristics of patient clearance clinical clinical care Cluster confirmed case confirmed cases COVID-19 COVID-19 infection COVID-19 pandemic COVID-19 testing cross-sectional cumulative Descriptive statistics disease epidemiological exposure to Fever followed by had no health institution healthcare Hospital admission identify IMPROVE Logistic regression analysis Loss of Smell loss of smell or taste majority Malaysia molecular Molecular assay molecular assays MOST multivariate logistic regression multivariate logistic regression analysis National objective observation observational study Patient positive Predictive risk risk factor Risk factors running nose SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 positivity seeking Selangor significantly study cohort subject subjects Symptom Taste tested Travel was used [DOI] 10.1371/journal.pone.0258671 PMC 바로가기 [Article Type] Research Article
Brief exposure to social media during the COVID-19 pandemic: Doom-scrolling has negative emotional consequences, but kindness-scrolling does notResearch Article Published on 2021-10-132022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, SARS, [키워드] adaptive Affect consequence Consequences COVID-19 detrimental emotional exposure group exposure to information media optimism pandemic positive reductions in risk threat YouTube [DOI] 10.1371/journal.pone.0257728 PMC 바로가기 [Article Type] Research Article