Adaptive immune determinants of viral clearance and protection in mouse models of SARS-CoV-2SARS-CoV-2의 마우스 모델에서 바이러스 제거 및 보호의 적응 면역 결정자Article Published on 2021-10-152022-09-11 Journal: Science Immunology [Category] SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus adaptive addition antibody Antibody Response B.1.351 caused cellular cellular immunity contribute convalescent coronavirus death defined determinant effective vaccine Effective vaccines highlight homologous humoral immune Immunity in vivo Infection mice mouse model Mouse models mRNA vaccination natural infection Primary infection promote Protective receive SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Vaccine variant viral clearance [DOI] 10.1126/sciimmunol.abl4509 PMC 바로가기 [Article Type] Article
The Effects of Heterologous Immunization with Prime-Boost COVID-19 Vaccination against SARS-CoV-2Review Published on 2021-10-112022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] acute respiratory syndrome antibody article BNT162b2 categories caused ChAdOx1-S conducted coronavirus COVID-19 COVID-19 pandemic dose Effect Google help Heterologous homologous Homologous vaccine immune response Immunity immunization implication IMPROVE mRNA vaccination mRNA vaccine mRNA-1273 pandemic participant populations reactogenicity recipient regimen robust SARS-CoV-2 searched Serious Adverse Event shown switching systematic review T-cell Response T-cells the vaccine vaccination Vaccine Vaccine hesitancy vaccine safety [DOI] 10.3390/vaccines9101163 PMC 바로가기 [Article Type] Review
Sewage as a Possible Transmission Vehicle During a Coronavirus Disease 2019 Outbreak in a Densely Populated Community: Guangzhou, China, April 2020인구 밀도가 높은 지역 사회에서 코로나 바이러스 질병 2019 발생 중 가능한 전송 수단으로서의 하수: 중국 광저우, 2020년 4월Article Published on 2021-10-052022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 치료기술, [키워드] apartment collected conducted COVID-19 COVID-19 outbreak demonstrated disease disease outbreak Genome sequencing Guangzhou Guangzhou, China hand handling highlighting homologous identify Incubation period Infectious disease infectious disease transmission investigated janitor management mode Outbreaks PCR test pipes positive RT-PCR resident retrospective cohort study Risk factors RT-PCR RT-PCR testing SARS-CoV-2 sewage sewage management. Spread squat toilet Symptoms Transmission transmission of SARS-CoV-2 vehicle working [DOI] 10.1093/cid/ciaa1494 PMC 바로가기 [Article Type] Article
Robust Neutralizing Antibody Levels Detected after Either SARS-CoV-2 Vaccination or One Year after InfectionArticle Published on 2021-10-052022-10-28 Journal: Viruses [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome addition antibodies AZD1222 BNT162b2 booster vaccination Cell concerning coronavirus Course COVID-19 Effectiveness examined healthy subject Heterologous homologous Immunity Immunoglobulin individual Infection Level mild infection neutralization Neutralization assay neutralization capacity neutralization titer neutralizing antibody parameter Patient regimen reliability remained SARS-CoV-2 SARS-CoV2 serology seropositive seropositive sample serum study participant subject Transmission vaccinated individuals vaccination Vaccines virus Volunteer Year [DOI] 10.3390/v13102003 PMC 바로가기 [Article Type] Article
Longitudinal Humoral Responses after COVID-19 Vaccination in Peritoneal and Hemodialysis Patients over Twelve WeeksArticle Published on 2021-10-042022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] age anti-S1 IgG antibody Anti-spike antibody binding BNT162b2 booster booster vaccination caused COVID-19 COVID-19 vaccination demonstrated dialysis Follow-up healthy control healthy controls Hemodialysis homologous Humoral response individual IQR longitudinal median mounted multicenter neutralization neutralizing antibody Patient patients Peritoneal dialysis reduced required response SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike second vaccination Seroconversion significantly susceptible vaccination Vaccination strategies Vaccination strategy vaccine-induced antibody variants of concern Week [DOI] 10.3390/vaccines9101130 PMC 바로가기 [Article Type] Article
Implications of a highly divergent dengue virus strain for cross-neutralization, protection, and vaccine immunityResearch article Published on 2021-10-042022-10-05 Journal: Cell Host & Microbe [Category] 비임상, [키워드] antibody antigenic appear canonical criteria cross-neutralization Dengue dengue virus DENV-4 disease divergent Efficacy Genotype Heterologous homologous Human humans immunized Infection inhibit Insects less mice neutralization neutralize Neutralizing passive transfer Pathogenesis Patient PROTECT protection Protective sequence sera serotype serum Strains vaccination Vaccine vaccine immunity virus [DOI] 10.1016/j.chom.2021.09.006 [Article Type] Research article
The strength of association between pre-and post-booster BNT162b2 anti-SARS-CoV-2 antibodies levels depends on the immunoassay사전 및 사후 부스터 BNT162b2 항 SARS-CoV-2 항체 수준 간의 연관성 강도는 면역 분석에 따라 다릅니다.Observational Study Published on 2021-10-012022-09-12 Journal: International Journal of Infectious Diseases [Category] MERS, SARS, 임상, 진단, [키워드] age anti-SARS-CoV-2 anti-SARS-CoV-2 antibody antibodies association baseline BNT162b2 BNT162b2 vaccine booster clinical effectiveness commercial immunoassay coronavirus disease correlation COVID-19 determine dose Elecsy enrolled Evidence females healthcare worker highest homologous humoral IgG immunoassay immunoassays initial LIAISON Pearson predicted Roche S-RBD SARS-CoV-2 SARS-CoV-2 IgG second dose seronegative serum serum antibody significantly the immunoassay vaccination Vaccine vaccine dose were assessed [DOI] 10.1016/j.ijid.2021.08.059 PMC 바로가기 [Article Type] Observational Study
Development of the Inactivated QazCovid-in Vaccine: Protective Efficacy of the Vaccine in Syrian HamstersMicrobiology Published on 2021-09-272022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] aluminum antibody Antigen body temperature buffer candidate vaccine clinical symptom coronavirus disease COVID-19 Culture develop development dose Effectiveness filtration formaldehyde gel hamster hamsters homologous hydroxide inactivated Inactivated vaccine indicated Infection Kazakhstan log lung observation period Particles patients Pneumonia Protective protective efficacy purified QazCovid-in Registered replicative retained saline solution SARS-CoV-2 Stress survival Syrian hamsters TCID the SARS-CoV-2 virus the vaccine trials Vaccine Vero Cell viral replication virion virulent virus virus-neutralizing antibody was used were used [DOI] 10.3389/fmicb.2021.720437 PMC 바로가기 [Article Type] Microbiology
Evolution of Diploid Progenitor Lung Cell Applications: From Optimized Biotechnological Substrates to Potential Active Pharmaceutical Ingredients in Respiratory Tract Regenerative MedicineReview Published on 2021-09-242022-10-31 Journal: Cells [Category] COVID-19, SARS, [키워드] active pharmaceutical ingredient administration Allogeneic API approach Burn Cell cell banking Cell therapy cell type COVID-19 COVID-19 patient diploid diploid progenitor cells effective effort Evolution FIVE function GMP good manufacturing practice homologous inflammatory lung disease ingredient Local lung lung cell lung cells lung tissue management Medicine MRC-5 cells Patient platform Potential produced progenitor progenitor cell recent regenerative regenerative medicine Research respiratory respiratory tract Safe substrate substrates Symptom syndrome therapeutic therapeutic use therapy tract Vaccine vaccine production vaccine substrate [DOI] 10.3390/cells10102526 PMC 바로가기 [Article Type] Review
A Combination Adjuvant for the Induction of Potent Antiviral Immune Responses for a Recombinant SARS-CoV-2 Protein Vaccine재조합 SARS-CoV-2 단백질 백신에 대한 강력한 항바이러스 면역 반응 유도를 위한 조합 보조제Immunology Published on 2021-09-162022-09-11 Journal: Frontiers in Immunology [Category] SARS, 변종, 진단, [키워드] activate Adaptive immune response adaptive immune responses adjuvant adjuvants antibody Antibody titers Antigen B.1.351 breadth candidate cellular response Combination cross-protection effective elicited ENhance Heterologous homologous Immune profile immune responses Immunity IMPROVE induction intranasal intranasal vaccine mice mucosal mucosal adjuvant N501Y mutation nanoemulsion (NE) neutralizing antibody titers NLRP3 P.1 variants passive transfer potent recombinant response RIG-I RIG-I agonist RNA robust SARS-CoV-2 SARS-CoV-2 vaccine SARS-CoV-2 variant SARS-CoV-2 variants Spike protein TLR TLRs transfer vaccination variant variants variety Viral viral challenge virus-neutralizing antibody [DOI] 10.3389/fimmu.2021.729189 PMC 바로가기 [Article Type] Immunology