Pleiotropy and epistasis within and between signaling pathways defines the genetic architecture of fungal virulence
신호 전달 경로 내 및 사이의 다면발광 및 상위성은 진균 독성의 유전적 구조를 정의합니다
Research Article
[키워드] Affect
amphotericin B
Analysis
antifungal drug resistance
approach
Author
avirulent
body temperature
CAMP
cascade
Cell
Cell signaling
cellular
cellular response
Cellular responses
characterization
Combination
complex
component
contribute
cross
Cryptococcal disease
Cryptococcus
cyclic AMP
disease
drug susceptibility
drugs
ENCODE
epistatic interaction
Europe
Extracellular
fungal
Genes
Genetic
genetic architecture
genetic difference
genetic differences
Genetic variation
glycerol
growth
highlight
human body
Infection
information
isolate
kinase
Lineage
locus
make up
mapping
microbial
modify
molecular
nucleotide
osmolarity
osmotic
oxidative
oxidative stress
oxidative stress resistance
pathogen
pathogenicity
Pathogens
pathway
phenotypic
phenotypic variation
physiological response
pleiotropic
polysaccharide capsule
progeny
promote
protein kinase
QTL
Quantitative
quantitative trait locus
regulate
regulator
sensitivity
Signal transduction
Signaling
signaling pathway
strain
Strains
Stress
temperate climates
thought
Tolerance
traits
underlie
Variation
virulence
virulent
[DOI] 10.1371/journal.pgen.1009313 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1371/journal.pgen.1009313 PMC 바로가기 [Article Type] Research Article