Phosphatidylglycerol and surfactant: A potential treatment for COVID-19?
Research article
[키워드] Activation
acute respiratory distress syndrome
addition
administration
approved
ARDSacute respiratory distress syndrome
benefit
cellular
component
concerning
Critically ill patient
damaged
damaged cells
DAMPdanger- or damage-associated molecular pattern
danger- or damage-associated molecular pattern
death
decrease
distress
drug
food
Hypothesis
ILInterleukin
IMPROVE
individual
Infants
Inflammation
innate immune system
interleukin
limit
lung
Lung function
Lung infection
Lung pathology
microbial
mitigate
Neonatal
NFκBnuclear factor kappa-light-chain-enhancer of activated B cells
non-infected cell
nuclear factor kappa-light-chain-enhancer of activated B cells
PAMPpathogen-associated molecular pattern
pathogen-associated molecular pattern
PGphosphatidylglycerol
phosphatidylglycerol
Potential treatment
Protein
Pulmonary edema
reducing
released
secretory phospholipase A2
sPLA2secretory phospholipase A2
Spread
suggested
syndrome
tension
tested
thought
TLRToll-like receptor
TNFαtumor necrosis factor-alpha
Toll-like receptor
treat
Treatment
tumor necrosis factor-alpha
Type II pneumocyte
utility
viral infection
with COVID-19
Work of breathing
[DOI] 10.1016/j.mehy.2020.110277 [Article Type] Research article
[DOI] 10.1016/j.mehy.2020.110277 [Article Type] Research article