sera – Page 17 – Communicable Diseases Research

Sera Metabolomics Characterization of Patients at Different Stages in Wuhan Identifies Critical Biomarkers of COVID-19

우한의 여러 단계에 있는 환자의 혈청 대사체학 특성 분석으로 COVID-19의 중요한 바이오마커 식별

Article

Published on 2022-05-022022-09-11
Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID19(2023년), MERS, SARS, 바이오마커,

Immunogenicity of BNT162b2 vaccine against the Alpha and Delta variants in immunocompromised patients with systemic inflammatory diseases

전신 염증성 질환이 있는 면역 저하 환자에서 알파 및 델타 변이체에 대한 BNT162b2 백신의 면역원성

Article

Published on 2022-05-012022-09-11
Journal: Annals of the rheumatic diseases [Category] COVID19(2023년), MERS, SARS, 변종, 임상, 진단,

[키워드] abrogated Alpha alpha and delta variants analysed anti-spike antibodies anti-spike antibody anti-Spike IgG B-cell B.1.617.2 BNT162b2 BNT162b2 vaccine Breakthrough infection breakthrough infections Control controls COVID-19 Delta delta variant Delta variants dose effort Endpoint evaluate exhibiting healthcare humoral Humoral response Immune escape immunocompromised individual immunocompromised individuals Immunocompromised patient Immunocompromised patients immunogenicity impairing IMPROVE individual infected with SARS-CoV-2 Inflammatory diseases Kinetics methotrexate mounted neutralisation neutralising Neutralising activity of BNT162b2 Other Patient primary endpoints Prospective raise regimen responses rituximab SARS-CoV-2 secondary Secondary endpoints sera Seroconversion Specific T-cell response strain Strains Support systemic inflammatory disease systemic inflammatory diseases T-cell T-cell Response T-cell responses therapeutic treated vaccination Vaccine Viral viral fitness
[DOI] 10.1136/annrheumdis-2021-221508 PMC 바로가기 [Article Type] Article

Elucidating Design Principles for Engineering Cell-Derived Vesicles to Inhibit SARS-CoV-2 Infection

SARS-CoV-2 감염을 억제하기 위해 세포 유래 소포를 엔지니어링하기 위한 설계 원리 설명

Article

Published on 2022-05-012022-09-11
Journal: Small (Weinheim an der Bergstrasse, Germany) [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료제,

[키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus addition administration antiviral efficacy binding affinities clinic coronavirus decoy decoys develop drug resistance Engineering evade Extracellular Extracellular vesicles feature foundation Health inhibit inhibitor inhibitors knowledge mAb mAbs monoclonal antibody nanovesicles. neutralization overcome Particle pathogen Pathogens principle provide Quantitative Recombinant protein repeated respiratory SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 virions sera several variant several variants severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 sustained Therapeutics therapy Toxicity Vesicle vesicles Viral viral infections virions
[DOI] 10.1002/smll.202200125 PMC 바로가기 [Article Type] Article

Vitamin D, vitamin D-binding protein, free vitamin D and COVID-19 mortality in hospitalized patients

Observational Study

Published on 2022-05-012022-10-05
Journal: The American journal of clinical nutrition [Category] 임상,

[키워드] 25-hydroxyvitamin D 28-day mortality 95% CI age albumin Analysis analyzed approved bioavailable vitamin D calculated case notes circulating clinical Comorbidities Concentration conducted coronavirus disease COVID-19 COVID-19 mortality DBP deficiency defined died ethics committee Free free vitamin D Frequency hospitalized COVID-19 patient hospitalized patient increased mortality Logistic regression male Mortality mortality risk mortality risks nonsurvivor Older outcomes patients with COVID-19 Protein relationship sera serum severe deficiency Sex Study protocol survivor Vitamin D Vitamin D status vitamin D-binding protein vitamin D–binding protein. were measured
[DOI] 10.1093/ajcn/nqac027 PMC 바로가기 [Article Type] Observational Study

Pathogenicity of SARS-CoV-2 Omicron (R346K) variant in Syrian hamsters and its cross-neutralization with different variants of concern

시리아 햄스터에서 SARS-CoV-2 오미크론(R346K) 변이체의 병원성 및 우려의 다른 변이체와의 교차 중화

Article

Published on 2022-05-012022-09-11
Journal: EBioMedicine [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술,

[키워드] Alpha antibody response against B.1 BA.1.1 Beta body weight caution Characteristics comparable Council COVID-19 cross-neutralization Delta delta variant demonstrated disease globe hamster hamsters immune response Infection interstitial pneumonia lead Lineage lung Lung disease Lungs Medical research moderate moderate to severe nasal nasal turbinate neutralization Neutralizing Neutralizing antibodies neutralizing antibody Neutralizing antibody response observation observations omicron Omicron (R346K) organ other variant other variants pathogenicity Preliminary data produced R346K reduction Reinfection respiratory respiratory tract SARS-CoV-2 SARS-CoV-2 variant sera severity supported Syrian hamsters throat swab titers titre variant variants of concern Viral Viral load viral replication viral RNA load Virology Virus shedding Weight reduction
[DOI] 10.1016/j.ebiom.2022.103997 PMC 바로가기 [Article Type] Article

The endogenous factors affecting the detection of serum SARS-CoV-2 IgG/IgM antibodies by ELISA

ELISA에 의한 혈청 SARS-CoV-2 IgG/IgM 항체 검출에 영향을 미치는 내인성 인자

Article

Published on 2022-05-012022-09-11
Journal: Journal of medical virology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 affecting antibody antinuclear antibody can be used caused Concentration control group controls coronavirus COVID-19 infection detect ELISA enzyme enzyme-linked immunosorbent assay Factor Factors false False positive False-positive false-positive rate group groups IgG IgG/IgM antibody IgM/IgG Infection interference factors. lead no significant difference patients without COVID-19 positive pregnant women reactivity respiratory Rheumatoid rheumatoid factor SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 IgM sera serum significantly higher turn urea was used
[DOI] 10.1002/jmv.27557 PMC 바로가기 [Article Type] Article

SARS-CoV-2 Omicron variant BA.2 neutralisation in sera of people with Comirnaty or CoronaVac vaccination, infection or breakthrough infection, Hong Kong, 2020 to 2022

SARS-CoV-2 Omicron 변이체 BA.2 중화, Comirnaty 또는 CoronaVac 백신 접종, 감염 또는 돌발성 감염, 홍콩, 2020년에서 2022년까지

Article

Published on 2022-05-012022-09-11
Journal: Eurosurveillance [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술,

[키워드] affecting antibody Beta BNT162b2 Breakthrough infection breakthrough infections circulation comparable CoronaVac Delta detectable dose elicited evaluated followed by help Hong Kong hybrid-immunity individual individuals Infection neutralisation neutralisation test neutralisation tests Neutralising Antibodies neutralising antibody neutralising antibody response neutralising antibody titre neutralising antibody titres neutralization omicron other variant other variants PRNT reduction response SARS-CoV-2 SARS-COV-2 infection sera significantly single vaccine subvariant BA.1 subvariant BA.2 symptomatic infection titre titres uninfected vaccination Vaccine vaccinee vaccinees variant viruses wild type
[DOI] 10.2807/1560-7917.ES.2022.27.18.2200178 PMC 바로가기 [Article Type] Article

Two SARS-CoV-2 serology assays detect antibodies in the sera of individuals diagnosed with SARS-CoV-2 Omicron variant

2개의 SARS-CoV-2 혈청학 분석은 SARS-CoV-2 Omicron 변이로 진단된 개인의 혈청에서 항체를 검출합니다

Article

Published on 2022-05-012022-09-11
Journal: Clinical biochemistry [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술,

[키워드] Abstract antibody Atellica IM COV2T COVID-19 detect diagnosed individual omicron SARS-CoV-2 sCOVG. sera serology assay variant
[DOI] 10.1016/j.clinbiochem.2022.02.010 PMC 바로가기 [Article Type] Article

Comparison of Six Serological Immunoassays for the Detection of SARS-CoV-2 Neutralizing Antibody Levels in the Vaccinated Population

백신 접종 집단에서 SARS-CoV-2 중화 항체 수준 검출을 위한 6가지 혈청 면역분석법의 비교

Comparative Study

Published on 2022-04-302022-09-11
Journal: Viruses [Category] COVID19(2023년), SARS, 진단, 치료기술,

[키워드] ACE2-RBD ACE2-RBD inhibition assay acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody AZ vaccine binding antibody blood sample BNT collected coronavirus correlation Correlation analysis Critical detection dose Efficacy enzyme enzyme immunoassays evaluate evaluated healthy herd immunity Immunity immunoassay immunoassays Level NAb titer NAb titers neutralization tests neutralizing antibody overall concordance Oxford-AstraZeneca participant Pfizer-BioNTech plaque reduction neutralization Population positive PRNT Quantitative respiratory Result SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 vaccines sera serologic assay serologic assays Serological assay serological assays severe acute respiratory syndrome Coronavirus sVNT tested vaccination Vaccine vaccine group virus neutralization test were measured
[DOI] 10.3390/v14050946 PMC 바로가기 [Article Type] Comparative Study

Seroreactivity of the Severe Acute Respiratory Syndrome Coronavirus 2 Recombinant S Protein, Receptor-Binding Domain, and Its Receptor-Binding Motif in COVID-19 Patients and Their Cross-Reactivity With Pre-COVID-19 Samples From Malaria-Endemic Areas

COVID-19 환자에서 중증 급성 호흡기 증후군 코로나바이러스 2 재조합 S 단백질, 수용체 결합 도메인 및 이의 수용체 결합 모티브의 혈청반응성과 말라리아 발병 지역의 코로나19 이전 샘플과의 교차 반응성

Article

Published on 2022-04-272022-09-11
Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 말라리아, 진단, 치료기술,

[키워드] absence acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition age anti-S antibody antibody Antibody Response Antibody responses Antigen antigens Area Asthma blood sample Blood samples Community Comorbidities conducted coronavirus coronavirus 2 COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients COVID-19 samples cross-reactive antibody cross-reactivity determine diabete diabetes disease Donor ELISA full-length Gender hospital IgG antibodies IgG antibody individual malaria malaria endemic-area participant Patient Plasmodium falciparum Plasmodium falciparum infection Pre-COVID-19 samples Protein RBD RBM Receptor-binding domain receptor-binding motif Recognition Recombinant S regions respiratory response responses S protein Sample SARS-CoV-2 SARS-CoV-2 proteins SARS-CoV-2 S SARS-CoV-2 S protein sera seroreactivity severe acute respiratory syndrome Coronavirus Study participants tested the receptor-binding domain the SARS-CoV-2 Treatment triggered weakened West while
[DOI] 10.3389/fimmu.2022.856033 PMC 바로가기 [Article Type] Article