COVID-19 vaccination elicits an evolving, cross-reactive antibody response to epitopes conserved with endemic coronavirus spike proteinsCOVID-19 백신 접종은 고유의 코로나바이러스 스파이크 단백질로 보존된 에피토프에 대한 진화하는 교차 반응성 항체 반응을 이끌어냅니다Article Published on 2022-07-052022-09-11 Journal: Cell Reports [Category] COVID19(2023년), MERS, SARS, 유전자 메커니즘, 진단, 치료기술, [키워드] Alanine antibody conserved coronavirus coronavirus spike protein CoV COVID-19 pandemic COVID-19 vaccination CoVs CP: Immunology CP: Microbiology cross-reactive cross-reactive antibody detectable elicit Endemic epitope Epitopes experiments homolog identify Immunity immunology longitudinal samples mechanism Microbiology mRNA mRNA-1273 mRNA-1273 vaccine multiplexed serology observé other coronavirus other coronaviruses phylogenetically reactivity regions residue SARS-CoV-2 SARS-CoV-2 epitope SARS-CoV-2 epitopes serology spike subject the vaccine trajectory triggered vaccination vaccine response vaccine-induced antibody response widespread [DOI] 10.1016/j.celrep.2022.111022 PMC 바로가기 [Article Type] Article
How to boost the boosters? A survey-experiment on the effectiveness of different policies aimed at enhancing acceptance of a “Seasonal” vaccination against COVID-19Randomized Controlled Trial Published on 2022-07-042022-10-05 Journal: Israel Journal of Health Policy Research [Category] 신종인플루엔자, 임상, [키워드] addition affected applied boost booster Compliance conditions country cross decrease demonstrated effective Effectiveness Efficacy ENhance experiment Factors Government greater group Health hypothetical Incentives individual information Intention less Linear regressions Logistic medium On-going pandemic pandemic participant perceived benefit Periodical vaccination positive predict Randomly repeated seasonal flu severity the disease the vaccine Type vaccination Vaccination acceptance vaccination against COVID-19 vaccination intentions Vaccination policies. Vaccine Vaccines variable was performed was related were measured while [DOI] 10.1186/s13584-022-00536-7 PMC 바로가기 [Article Type] Randomized Controlled Trial
Exosomes decorated with a recombinant SARS-CoV-2 receptor-binding domain as an inhalable COVID-19 vaccine Research Published on 2022-07-042022-10-05 Journal: Nature biomedical engineering [Category] COVID19(2023년), SARS, 임상, 치료기술, 치료법, 치료제, [키워드] acute respiratory syndrome airway antibodies approved CD4+ CD8+ T cell coronavirus COVID-19 vaccine cytokine expression profile domain dose elicit elicited ENhance Exosome hamsters Immunity Infection Inflammatory Intramuscular injection live SARS-CoV-2 lung parenchyma Lungs mice mRNA vaccine mucosal IgA response Preclinical Testing RBD RBD-specific IgG reduced SARS-CoV-2 SARS-CoV-2 pseudovirus severe pneumonia temperature the RBD the vaccine Vaccine vaccine candidates Virus-like particle [DOI] 10.1038/s41551-022-00902-5 [Article Type] Research
Differences in Immunological Evasion of the Delta (B.1.617.2) and Omicron (B.1.1.529) SARS-CoV-2 Variants: A Retrospective Study on the Veneto Region’s Population델타(B.1.617.2)와 오미크론(B.1.1.529) SARS-CoV-2 변이체의 면역학적 회피 차이: 베네토 지역 인구에 대한 후향적 연구Article Published on 2022-07-042022-09-11 Journal: International Journal of Environmental Research an [Category] COVID19(2023년), SARS, 변종, [키워드] active immunization addition Affect B.1.1.529 B.1.617.2 booster vaccination Coverage Delta difference dose effective Effectiveness Factor form immunization immunological immunological evasion immunological protection incidence rate infected individual Infection Italy less minor multivariable natural immunity offer offered omicron Omicron variant performed Population receiving regimen Region Reinfection Retrospective study SARS-CoV-2 SARS-CoV-2 delta SARS-COV-2 infection SARS-CoV-2 infections survival analysis the SARS-CoV-2 the vaccine Vaccines variant variants Veneto Veneto region viral variant VOCs [DOI] 10.3390/ijerph19138179 PMC 바로가기 [Article Type] Article
COVID-19 vaccination efficacy in numbers including SARS-CoV-2 variants and age comparison: a meta-analysis of randomized clinical trialsSARS-CoV-2 변이체 및 연령 비교를 포함한 숫자로 보는 COVID-19 백신 접종 효능: 무작위 임상 시험의 메타 분석Meta-Analysis Published on 2022-07-032022-09-11 Journal: Annals of Clinical Microbiology and Antimicrobials [Category] COVID19(2023년), SARS, 변종, 임상, [키워드] 95% CI age Analysis analyzed caused clinical examination clinical trial clinical trials Cohort Coronavirus infection COVID-19 COVID-19 pandemic COVID-19 vaccination COVID-19 vaccine COVID-19 vaccines databases death decrease Effect effective Efficacy group groups Hospitalization hospitalizations Infection Meta-analysis Mortality New new SARS-CoV-2 Prevent randomized clinical trial Relative risk required risk SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants severe COVID-19 severe infections symptomatic text the vaccine vaccination Vaccine variants variants of SARS-CoV-2 was used [DOI] 10.1186/s12941-022-00525-3 PMC 바로가기 [Article Type] Meta-Analysis
Hybrid immunity against COVID-19 in different countries with a special emphasis on the Indian scenario during the Omicron period오미크론 기간 동안 인도 시나리오에 특히 중점을 둔 여러 국가의 COVID-19에 대한 하이브리드 면역Article Published on 2022-07-012022-09-11 Journal: International immunopharmacology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] Antibody Response available data country COVID-19 COVID-19 vaccine cumulative cumulative effect described dose herd immunity hybrid Hybrid immunity Immunity India individual infected individual Infection less molecular basis omicron produced provide robust SARS-CoV-2 SARS-CoV-2 variants scientist the disease the vaccine Third wave in India. Vaccine virus [DOI] 10.1016/j.intimp.2022.108766 PMC 바로가기 [Article Type] Article
Low-frequency variants in mildly symptomatic vaccine breakthrough infections presents a doubled-edged sword경미한 증상이 있는 백신 획기적인 감염의 저주파 변이는 양날의 검을 제시합니다Article Published on 2022-07-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, [키워드] absence acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Ad26 association BNT162b2 case study characterized coronavirus Critical Efficacy Epidemiology epitope Epitopes Evolution Genetic Genetic variation genetics highlight immune individual Infection L18F Mutation Pfizer Phylogenetic question raised reduced reducing replicative SARS Coronavirus SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe symptoms Symptom symptomatic the vaccine Transmission vaccination Vaccination Status Vaccine vaccine breakthrough infection Vaccines variant variants of concern virus virus classification VoC VOCs widespread [DOI] 10.1002/jmv.27726 PMC 바로가기 [Article Type] Article
Antibody response to SARS-CoV-2 vaccination following typical and three-dose dosing schedules in multiple sclerosis patients treated with disease modifying therapies질병 변형 요법으로 치료받는 다발성 경화증 환자에서 일반적인 3회 투여 일정에 따른 SARS-CoV-2 백신 접종에 대한 항체 반응Article Published on 2022-07-012022-09-12 Journal: Multiple sclerosis and related disorders [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] age anti-CD20 anti-CD20 treatment antibody benefit COVID-19 disease Disease modifying treatment dose dosing schedule fumarate humoral immune system immunization Immunocompromised interferon medication mRNA vaccination MS multiple sclerosis Part Patient patients patients treated retrospective SARS-CoV-2 SARS-CoV-2 vaccination SARS-CoV-2 virus spike tested the vaccine therapy treated treated patients treatment with anti-CD20 vaccination Vaccine vaccine response [DOI] 10.1016/j.msard.2022.103856 PMC 바로가기 [Article Type] Article
The impact of COVID-19 vaccination program in the Republic of San Marino: focus on effectiveness of Gam-COVID-VacResearch article Published on 2022-07-012022-10-05 Journal: Clinical microbiology and infection : the official [Category] COVID19(2023년), SARS, 변종, 임상, [키워드] adenovirus-based adjusted bimester BNT162b2 calculated concerning conducted COVID-19 COVID-19 vaccination COVID-19-related death declining demonstrated dose Effectiveness Gam COVID-Vac Gam-COVID-Vac Hospitalization hospitalizations incidence rate multivariable objective peaked Phase 3 population level protection Rate Ratio Regression model reported Result retrospective SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccination second dose Sputnik V study period subject the vaccine vaccination vaccination schedule Vaccine variant with COVID-19 [DOI] 10.1016/j.cmi.2022.06.026 [Article Type] Research article
A machine learning-based approach to determine infection status in recipients of BBV152 (Covaxin) whole-virion inactivated SARS-CoV-2 vaccine for serological surveys혈청학적 조사를 위한 BBV152(Covaxin) 전체 비리온 비활성화 SARS-CoV-2 백신의 수혜자의 감염 상태를 결정하기 위한 기계 학습 기반 접근 방식Article Published on 2022-07-012022-09-11 Journal: Computers in biology and medicine [Category] COVID19(2023년), SARS, 치료법, [키워드] age antibody antigens applied approach assessment assessments BBV152 Breakthrough infection can be used Clustering Consensus Covaxin COVID-19 COVID-19 pandemic Data science dataset Delta determine dose doses effective Effectiveness Ensemble methods generate help immune response inactivated Infection machine machine learning ML model neutralization Neutralization assay neutralize nucleocapsid antigens Population predicted premise Protein random recipient recipients SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccine sequence sequences serological survey Sex spike Spike protein statistical subject subjects subset Support the vaccine type strain uninfected Vaccine vaccine response viral evolution Viral proteins virion wild type wild-type strain [DOI] 10.1016/j.compbiomed.2022.105419 PMC 바로가기 [Article Type] Article