therapeutic targets

[키워드] a major abundance Affect Algorithm Antibiotic resistance approach approaches array assortment Author Bacterial bacterial gene bacterial genes benefit bioinformatics candidate gene changes in Combination conjunction conserved dataset deep sequencing deleted determinant determinants Determining diagnostic dissect Diversity DNA binding E. coli effective effort enrichment Escherichia Escherichia coli Factor fitness Follow-up analysis Footprinting found Gene Genes Genetic Genome genomes highest highlight homologue homologues Host hypothetical identify increasingly independent Infection infections insertion investigator investigators isolates Meningitis molecular mouse model Mutagenesis mutant novel observation observations pathogen Pathogenesis pathogenic pathogenic strain pathogenic strains Pathogens phenotypic phenotypic variation phylogenetic distribution promote Quantitative reported required Research resource saturated Sepsis Sequencing shown strain Strains suggested therapeutic therapeutic targets Therapies Tn-seq to define trait transcriptional repressor transposon urinary tract infections variant Variation virulence virulence gene widespread zebrafish
[DOI] 10.1371/journal.pgen.1003716 PMC 바로가기 [Article Type] Research Article